Location: Aquatic Animal Health Research
Title: Gene expression profiling of white bass (Morone chrysops) and hybrid striped bass (M. chrysops x M. saxatilis) gill over time following Flavobacterium columnare exposureAuthor
Submitted to: NIH Gene Expression Omnibus (GEO) Database
Publication Type: Database / Dataset Publication Acceptance Date: 10/23/2023 Publication Date: 4/25/2024 Citation: Andersen, L.K., Abernathy, J.W. 2024. Gene expression profiling of white bass (Morone chrysops) and hybrid striped bass (M. chrysops x M. saxatilis) gill over time following Flavobacterium columnare exposure. NIH Gene Expression Omnibus (GEO) Database. GSE246056. Interpretive Summary: Technical Abstract: Columnaris is a prevalent disease in freshwater environments worldwide caused by the ubiquitous aquatic bacterium Flavobacterium spp. Adhesion to the external mucosal surfaces of fishes is the initial stage of infection, and the gills specifically have been identified as both a primary target and release site for this pathogen. Previous research has indicated that a predominant US aquaculture product, the hybrid striped bass (Morone chrysops x M. saxatilis), is more susceptible to infection with Flavobacterium columnare than the maternal white bass (M. chrysops) parental species. Therefore, to further elucidate the differences between these fish we conducted a transcriptomic profiling study examining the differences of gene expression in gill mucosal tissue over time after exposure to F. columnare. Combined with previous work, these data provide a greater understanding of host immune response to a common pathogen in moronids. Raw sequencing reads and processed gene expression data has been submitted to the National Center for Biotechnology Information (NCBI) Gene Expression Omnibus (GEO) and is available to the public under the accession number GSE246056. |