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Research Project: Metabolic and Epigenetic Regulation of Nutritional Metabolism

Location: Children's Nutrition Research Center

Title: The field of population epigenetics is failing on rigor and reproducibility

Author
item WATERLAND, ROBERT - Children'S Nutrition Research Center (CNRC)

Submitted to: Cancer Letters
Publication Type: Other
Publication Acceptance Date: 11/28/2023
Publication Date: 12/8/2023
Citation: Waterland, R. 2023. The field of population epigenetics is failing on rigor and reproducibility. Cancer Letters. 49(45):27-28. Available at: https://cancerletter.com/letter-to-the-editor/20231208_5/.

Interpretive Summary:

Technical Abstract: To the editor, Following is an email I sent a month ago to the NIH Director and Directors of 13 Institutes that fund research in human population epigenetics. The subject line read: "The field of population epigenetics is failing on rigor and reproducibility." My email was addressed to then NIH Acting Director Lawrence Tabak, current NIH Director (and former NCI Director) Monica Bertagnolli, NEI Director Michael Chiang, NHGRI Director Eric Green, NHLBI Director Gary Gibbons, NIA Director Richard Hodes, NIAAA Director George Koob, NIAID Director Jeanne Marrazzo, NIAMS Director Lindsey Criswell, NICHD Director Diana Bianchi, NIDA Director Nora Volkow, NIDDK Director Griffin Rodgers, NIEHS Director Rick Woychik, and NIMH Director Joshua Gordon. While I await their reply, in the spirit of open science, I would be delighted if you would consider making this an open letter by publishing it in The Cancer Letter.