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ARS Home » Northeast Area » Boston, Massachusetts » Jean Mayer Human Nutrition Research Center On Aging » Research » Publications at this Location » Publication #414712
Research Project: Nutrition, Sarcopenia, Physical Function, and Skeletal Muscle Capacity During Aging

Location: Jean Mayer Human Nutrition Research Center On Aging

Title: Sarcopenia: an emerging syndrome of advancing age

Author
item FIELDING, ROGER - Jean Mayer Human Nutrition Research Center On Aging At Tufts University

Submitted to: Calcified Tissues International
Publication Type: Review Article
Publication Acceptance Date: 12/17/2023
Publication Date: 1/8/2024
Citation: Fielding, R. 2024. Sarcopenia: an emerging syndrome of advancing age. Calcified Tissues International. https://doi.org/10.1007/s00223-023-01175-z.
DOI: https://doi.org/10.1007/s00223-023-01175-z

Interpretive Summary:

Technical Abstract: Underlying the age-related declines in motor function, loss of mobility, and mobility disability is the progressive decline in skeletal muscle mass and muscle performance, sarcopenia, that begins in mid-life and continues throughout the lifespan [1, 2]. Defined as the age-associated loss of skeletal muscle mass and function, sarcopenia is a key component of the declines in motor function and the increased risk of mobility disability, falls, fractures, and mortality with advancing age [3]. In this current special issue of CTI, we have assembled a series of critical reviews and original work that embody the current state of the art related to our understanding of the pathogenesis, clinical implications and potential targets of therapeutic interventions for this syndrome.