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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Ruminant Diseases and Immunology Research » Research » Publications at this Location » Publication #415878
Research Project: Host-pathogen Interactions and Control Strategies for Bacterial Respiratory Pathogens in Cattle

Location: Ruminant Diseases and Immunology Research

Title: Complete genome sequence of a Histophilus somni Strain 91 i from a beef calf with pneumonia

Author
item MENGHWAR, HARISH - Oak Ridge Institute For Science And Education (ORISE)
item Ma, Hao
item Briggs, Robert
item Tatum, Fred
item Casas, Eduardo
item Dassanayake, Rohana

Submitted to: Microbiology Resource Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 8/1/2024
Publication Date: 9/6/2024
Citation: Menghwar, H., Ma, H., Briggs, R.E., Tatum, F.M., Casas, E., Dassanayake, R.P. 2024. Complete genome sequence of a Histophilus somni Strain 91 i from a beef calf with pneumonia. Microbiology Resource Announcements. Article e00570-24. https://doi.org/10.1128/mra.00570-24.
DOI: https://doi.org/10.1128/mra.00570-24

Interpretive Summary: Histophilus somni is typically isolated as a commensal of bovine and ovine mucus membranes such as the nasal passage, prepuce, and vagina. Although H. somni is an important pathogen in the bovine respiratory disease complex, the mechanisms that cause its virulence are still poorly understood. In order to understand its virulence determinants, a complete genome sequencing was carried out on an isolate recovered from pneumonic calf lungs. The gene arrangement and virulent genes of the new isolate were very similar to those of H. somni isolate 2338.

Technical Abstract: Histophilus somni is an important causative agent of bovine respiratory disease complex. Here, we report the complete genome sequence of a Histophilus somni strain 91, which was isolated from a pneumonic lung tissue sample collected from a beef calf.