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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Infectious Bacterial Diseases Research » Research » Publications at this Location » Publication #419981

Research Project: Intervention Strategies for Spirochete Diseases

Location: Infectious Bacterial Diseases Research

Title: Leptospira gorisiae sp. nov, L. cinconiae sp. nov, L. mgodei sp. nov, L. milleri sp. nov and L. iowaensis sp. nov: five new species isolated from water sources in the Midwestern United States

Author
item HAMOND, CAMILLA - Diagnostic Virology Laboratory/ National Veterinary Services Laboratories
item Tibbs-Cortes, Bienvenido
item FERNANDES, LUIS - Oak Ridge Institute For Science And Education (ORISE)
item LECOUNT, KAREN - Diagnostic Virology Laboratory/ National Veterinary Services Laboratories
item Putz, Ellie
item ANDERSON, TAMMY - Diagnostic Virology Laboratory/ National Veterinary Services Laboratories
item CAMP, PATRICK - Diagnostic Virology Laboratory/ National Veterinary Services Laboratories
item STUBER, TOD - Diagnostic Virology Laboratory/ National Veterinary Services Laboratories
item HICKS, JESSICA - Diagnostic Virology Laboratory/ National Veterinary Services Laboratories
item VAN DER LINDEN, HANS - University Of Amsterdam
item DOS SANTOS-RIBEIRO, PRISCYLA - University Of Amsterdam
item Bayles, Darrell
item SCHLATER, LINDA - Diagnostic Virology Laboratory/ National Veterinary Services Laboratories
item Nally, Jarlath

Submitted to: International Journal of Systematic and Evolutionary Microbiology
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 11/14/2024
Publication Date: 1/7/2025
Citation: Hamond, C., Tibbs-Cortes, B.W., Fernandes, L.G., Lecount, K., Putz, E.J., Anderson, T., Camp, P., Stuber, T., Hicks, J., Van Der Linden, H., Dos Santos-Ribeiro, P., Bayles, D.O., Schlater, L., Nally, J.E. 2025. Leptospira gorisiae sp. nov, L. cinconiae sp. nov, L. mgodei sp. nov, L. milleri sp. nov and L. iowaensis sp. nov: five new species isolated from water sources in the Midwestern United States. International Journal of Systematic and Evolutionary Microbiology. https://doi.org/10.1099/ijsem.0.006595.
DOI: https://doi.org/10.1099/ijsem.0.006595

Interpretive Summary: Leptospirosis is a global zoonotic disease of animals and humans that is caused by pathogenic species of Leptospira. Here, we describe the isolation and characterization of a two new pathogenic species of Leptospira, and three new saprophytic species of Leptospira, that were isolated from water samples in Iowa. These new species are designated Leptospira gorisiae sp. nov, L. cinconiae sp. nov, L. mgodei sp. nov, L. milleri sp. nov and L. iowaensis sp. nov. These new species also appear to be new serovars of Leptospira which are not currently detected by the standard serology diagnostic assays for Leptospira.

Technical Abstract: Isolates of Leptospira spp. were cultured from water sources at five different sites in central Iowa in the Midwestern United States and characterized by whole-genome sequencing. Isolates were helix-shaped and motile. Genome sequence analyses determined that the isolates could be clearly distinguished from other species described in the genus Leptospira and included one species that belonged to the pathogen subclade P1, one species that belonged to the pathogen subclade P2, and three species that belonged to the saprophyte subclade S1. The names Leptospira gorisiae sp. nov. (type strain WS92.C1T=NVSL-WS92.C1T=KIT0303T), Leptospira cinconiae sp. nov. (type strain WS58.C1T=NVSL-WS58.C1T=KIT0304T), Leptospira mgodei sp. nov. (type strain WS4.C2T=NVSL.WS4.C2T=KIT0305T), Leptospira iowaensis sp. nov. (type strain WS39.C2T=NVSL-WS39.C2T=KIT0306T), and Leptospira milleri sp. nov. (type strain WS60.C2T=NVSL-WS60.C2T=KIT0307T) are proposed.