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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Food Safety and Enteric Pathogens Research » Research » Publications at this Location » Publication #421836
Research Project: Analysis of Genetic Factors that Increase Foodborne Pathogen Fitness, Virulence, and Antimicrobial Resistance Transfer, to Identify Interventions against Salmonella and Campylobacter in Food Animals

Location: Food Safety and Enteric Pathogens Research

Title: USDA Salmonella vaccine reduces colonization and dissemination of serovar Enteritidis in chickens

Author
item WHELAN, SAMUEL - Oak Ridge Institute For Science And Education (ORISE)
item Bearson, Bradley - Brad
item ENCINONSA, MAYA - Oak Ridge Institute For Science And Education (ORISE)
item NEUPANE, DURGA - Oak Ridge Institute For Science And Education (ORISE)
item Bearson, Shawn

Submitted to: Conference Research Workers Disease Meeting
Publication Type: Abstract Only
Publication Acceptance Date: 10/21/2024
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: OBJECTIVE: Nontyphoidal Salmonella enterica is a leading cause of foodborne illness. Among the most common serotypes globally, Salmonella enterica serovar Enteritidis (S. Enteritidis) frequently colonizes poultry without causing signs of disease. Recently, a strain of S. Enteritidis with decreased susceptibility to ciprofloxacin (DSC), a critical antibiotic prescribed for complicated human infections, has emerged in chickens with the gyrA gene encoding a D87Y modification. In the current study, vaccination with the cross-protective, cross-species USDA BBS 866 Salmonella DIVA vaccine was evaluated for reduction of intestinal colonization and systemic dissemination of DSC S. Enteritidis in broiler chickens.