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Title: (ALL TRANS)-2,4,6,8,10,12-TETRADECA-1,14-HEXENEDIAL, A NEW PIGMENT FROM CONIDIOBOLUS PAULUS

Author
item Vesonder, Ronald

Submitted to: Journal of Natural Products
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 2/6/1996
Publication Date: N/A
Citation: N/A

Interpretive Summary: In a program to screen for agents capable of producing responses in biological systems, the coloring substance of a fungus called Conidiobolus was identified as a lead. Two things were accomplished in this study: first, the new, apparently non-toxic coloring matter called paulal was isolated and fully characterized; second, paulal was found to have antibiotic activity. Paulal may be of interest to the food industry as a bright-red coloring additive.

Technical Abstract: A study of the coloring matter produced by Conidiobolus paulus Drechsler ATTC 12942 on potato-dextrose medium led to the discovery of a new dialdehyde unsaturated metabolite, tetradeca-E2,E4,E6,E8, E10,E12-hexene-1,14-dial. The pigment was characterized by mass spectrometry and 1H- and 13C-NMR. The pigment inhibited both gram- positive and gram-negative bacteria.