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ARS Home » Research » Publications at this Location » Publication #59425
Title: EXPERIMENTAL CHLAMYDIAL INFECTIONS IN GNOTOBIOTIC PIGS

Author
item ROGERS, DOUGLAS - UNIV OF NEBRASKA-LINCOLN
item ANDERSEN, ARTHUR

Submitted to: American Association of Swine Practitioners Proceedings
Publication Type: Proceedings
Publication Acceptance Date: 3/5/1995
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: The goal of the research was to determine whether 2 different swine isolates would cause disease in gnotobiotic piglets. The first isolate was recovered from the upper respiratory tract of a pig with pneumonia, and the second isolate was recovered from intestinal contents of a pig with enteritis. The respiratory disease isolate was inoculated intralaryngeally yinto 15 piglets. Three piglets were necropsied every 7 days, starting on day 7 post infection (PI). Pneumonia was present at days 7, 14, and 21 PI. Evidence of resorption of pneumonia was present at days 28 and 35 PI. The piglets also had enteritis from day 4 to day 16 PI. The second isolate was mixed with milk and fed to 14 gnotobiotic piglets. Four to 5 piglets were necropsied on each of days 7, 10, and 14 PI. The chlamydia produced a moderate enteritis with transient inappetence lasting about one week. Histological lesions at days 7 and 10 PI showed moderate multifocal damage to the intestinal mucosa. Lesions were less severe at 14 days PI. The results prove that chlamydia can produce both pneumonia and enteritis in young pigs.