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ARS Home » Plains Area » Houston, Texas » Children's Nutrition Research Center » Research » Publications at this Location » Publication #65410

Title: GENETICALLY DIVERSE PIG MODELS IN NUTRITION RESEARCH RELATED TO LIPOPROTEINAND CHOLESTEROL METABOLISM

Author
item Mersmann, Harry
item POND, WILSON - BAYLOR COLL OF MEDICINE

Submitted to: International Symposium: Swine And Biomedical Research
Publication Type: Book / Chapter
Publication Acceptance Date: 4/15/1996
Publication Date: N/A
Citation: N/A

Interpretive Summary: Book chapter: No summary needed.

Technical Abstract: The pig is a widely accepted animal model for nutrition research related to growth and development, atherogenesis, obesity, and lipoprotein and cholesterol metabolism. We review current knowledge of lipoprotein metabolism in pigs and describe research in populations of genetically diverse swine. Specifically, we report the results of experiments showing that dietary cholesterol during neonatal life affects atherogenesis and indices of central nervous system development and lipid metabolism differentially in genetically obese and lean pigs and in pigs selected genetically for low or high plasma total cholesterol.