Author
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SCHANLER, RICHARD - BAYLOR COLL OF MEDICINE |
Submitted to: Book Chapter
Publication Type: Book / Chapter Publication Acceptance Date: 1/10/1996 Publication Date: N/A Citation: N/A Interpretive Summary: Technical Abstract: The growth, nutrient balance, radius bone mineral content, and serum biochemical indices of nutritional status in preterm infants fed their mothers' milk fortified with protein and minerals were evaluated to determine whether fortified human milk met nutritional needs based on intrauterine estimates. The study was conducted during hospitalization and spanned an interval that began with the minimum body weight and ended with a body weight of 2.0 kg. All infants required higher volumes of milk (180 ml/kg-1/d-1) than usually ordered to meet the expected daily weight gain (15 g/kg-1/d-1). Intrauterine estimates of nitrogen and minerals were achieved by feeding fortified human milk. Despite achieving intrauterine mineral accretion, radius bone mineral content remained below intrauterine expectations. There was a positive correlation, however, between radius bone mineral content and net calcium retention and bone mineral content significantly increased during the study interval. Intrauterine accretion rates for nitrogen and minerals can be achieved by feeding preterm infants high volumes of human milk fortified with protein and minerals. There remain concerns, however, that postnatal bone mineralization and overall rates of growth may not be optimum even with high milk intakes. |