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ARS Home » Research » Publications at this Location » Publication #72597
Title: EXTRACTION OF NATURAL PRODUCTS WITH SUPERCRITICAL FLUIDS

Author
item JARVENPAA, ELIA - UNIV OF TURKU, FINLAND
item HUOPALAHTI, R - UNIV OF TURKU, FINLAND
item TAYLOR, SCOTT
item KING, JERRY

Submitted to: Great Lakes Regional American Chemical Society Symposium
Publication Type: Abstract Only
Publication Acceptance Date: 10/29/1996
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: Supercritical fluid extraction (SFE) using SC-CO2 as a fluid can be a convenient substitute for organic solvents in extraction methods required for the isolation of bioactive compounds from natural matrices. Such SFE methods have much in common with techniques developed for environmental contaminants, foods, and toxicant analysis, but can be highly matrix dependent. Among the problems that must be addressed are the presence of coextractives (often lipid components), the presence of water, a suitable analysis method consistent with the resultant SF extract and ability to overcome analyte/matrix interactions which compromise recovery. In this presentation, these constraints and solutions to overcoming them, will be highlighted. For example, matrix morphology and water content are key parameters in optimizing the recovery of psoralen-type furocoumarins from the plant matrix, while reducing or isolating coextractive interferences in SFE is critical for the HPLC determination of deoxynivalenol (DON) content in oats. Addressing the latter problem is also critical in the development of a SFE/immunoassay-based method for DON. These examples and others will be used to emphasis the various aspects of successfully applying SFE for the analytical and preparative isolation of substances from natural products.