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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Virus and Prion Research » Research » Publications at this Location » Publication #75496
Title: VACCINATION FOR BOVINE VIRAL DIARRHEA VIRUS

Author
item Bolin, Steven - Steve

Submitted to: Meeting Abstract
Publication Type: Proceedings
Publication Acceptance Date: 6/25/1996
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: Bovine viral diarrhea virus (BVDV) is an economically important viral pathogen of cattle. The virus is prevalent in most cattle populations throughout the world. Modified-live virus vaccines for control of BVDV have been available in the United States for 30 years. Inactivated-virus vaccines have been available for about 15 years. Both types of vaccines are efficacious when used properly, and when booster dosages of vaccine are administered at regular intervals. Recent changes in the antigenic nature of BVDV has led to the emergence of viruses that can escape immunity induced by inactivated-virus vaccines when the interval between administration of booster dosages of vaccine is prolonged. Modification of inactivated- virus vaccines to include multiple antigenic variants of BVDV may extend the duration of protective immunity. At this time, there is no evidence that suggests modified-live virus vaccines require modification.