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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Virus and Prion Research » Research » Publications at this Location » Publication #76462
Title: ISOLATION OF VIRULENT TRANSMISSIBLE GASTROENTERITIS VIRUS FROM A SOW 18 MONTHS POST-EXPOSOURE

Author
item Woods, Roger
item Wesley, Ronald

Submitted to: International Symposium on Coronviruses and Arteriviruses Proceedings
Publication Type: Abstract Only
Publication Acceptance Date: 5/10/1997
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: A sow hyperimmunized with virulent transmissible gastroenteritis virus (TGEV) shed virulent virus in her feces for 18 months. The virus was isolated from rectal swabs beginning 2 days postexposure (PE) and continued at irregular intervals. Virus shedding was detected on 24 separate occasions. The titer of the virus shed ranged from 1 x 10**2 pfu/ml to 7.5 x 10**3 pfu/ml, while the duration of the shedding ranged from 1 to 5 consecutive days. Inoculation of 3-day-old piglets with TGEV isolated from the sow proved the virus was virulent throughout the study. Virulent TGEV was isolated from the spleen, mesenteric lymph nodes, and the liver of the sow 544 days PE. This study demonstrates an apparently healthy sow can be a reservoir and shed virulent TGEV for an extended period of time.