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Submitted to: American Dairy Science Association Proceedings
Publication Type: Abstract Only Publication Acceptance Date: 3/18/1997 Publication Date: N/A Citation: N/A Interpretive Summary: Technical Abstract: Bovine viral diarrhea virus (BVDV) is the most economically important viral pathogen in the United States. Two biotypes of BVDV, termed cytopathic and noncytopathic, exist. The cytopathic viral biotype is extremely rare and seldom associated with primary postnatal disease processes. The noncytopathic viral biotype is prevalent, routinely isolated from disease outbreaks, and may be highly virulent. Recent advances in research on BVD and disease induced by BVDV has resulted in the identification of two distinct genotypes of virus. The viral genotypes differ markedly in their genetic material and in their antigenic nature. Many of the problems associated with failure of protection after vaccination for BVDV have been explained by the identification of two viral genotypes. Currently, there are highly virulent noncytopathic BVDV of genotype 2 circulating in beef and dairy cattle in North America. Those BVDV are capable of killing adult tcattle and have resulted in substantial economic losses in afflicted herds Current vaccines for BVDV appear partially protective against the virulent BVDV, but may not prevent clinical disease or reproductive failure under certain circumstances. In addition to recent findings on classification of BVDV, the importance of BVDV as a primary viral pathogen of cattle and the role of BVDV in reproductive failure will be discussed. |
