Skip to main content
ARS Home » Research » Publications at this Location » Publication #91411
Title: A NON-LINEAR DYNAMIC SIMULATION MODEL FOR XENOBIOTIC TRANSPORT AND WHOLE PLANT ALLOCATION FOLLOWING FOLIAR APPLICATION. II. MODEL VALIDATION

Author
item SATCHIVI, NORBERT - UNIV OF ILLINOIS
item Stoller, Edward
item Wax, Loyd
item BRISKIN, DONALD - UNIV OF ILLINOIS

Submitted to: Pesticide Biochemistry and Physiology
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 5/9/2000
Publication Date: N/A
Citation: N/A

Interpretive Summary: There is a need to predict absorption, translocation, and activity of foliar applied pesticides in order to enhance pesticide efficacy and to develop new products that have desired biological properties that will allow expression of maximum activity without adverse environmental consequences. We have developed a computer simulation model (ERMESSE) that makes such predictions and described its components in a previous paper. In this paper we test the model's prediction accuracy of absorption, translocation and distribution of a number of herbicides against previously published results reported in the literature. The simulated values are very close to the reported values for a number of herbicides indicating that the descriptions and assumptions of the plant processes in the model closely parallel those in the plant. This model will be useful to researchers in public and private institutions that develop\design pesticides for maximum biological activity and want to understand all the ramifications for weed management.

Technical Abstract: A validation study was performed for a non-linear computer simulation model ("ERMESSE') describing xenobiotic absorption, translocation and metabolism. Validation involved comparison of predicted xenobiotic behavior with actual data for sulfonylurea, pyridine carboxylic acid, aryloxyakanoic acid, arylpropanoic acid, imidazolinone and unclassified herbicides. Computer simulations were performed with hypothetical parameters describing the plant, the physicochemical properties for each herbicide and environmental parameters based upon the actual experimental studies. Simulated and actual absorption, translocation, distribution and metabolism are compared by determining the ratio of simulated/actual or vice-versa. Overall, simulated herbicide absorption, translocation and distribution appears close to actual values with the ratio simulated/actual fluctuating between 1.0 and 2.0. However, theoretical herbicide metabolism differed from that observed for actual data and this may reflect the model assumption of constant, non-inducible metabolism levels.