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Title: A NEW SEROTYPE ADENOVIRUS ISOLATED FROM A GOAT IN THE UNITED STATES

Author
item Lehmkuhl, Howard
item DEBEY, BRAD - UNIV. CA-DAVIS,TULARE,CA
item Cutlip, Randall

Submitted to: Journal of Veterinary Diagnostic Investigation
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 6/19/2000
Publication Date: N/A
Citation: N/A

Interpretive Summary: Respiratory and enteric disease is a major cause of economic loss to the sheep industry in the United States. Adenoviruses are known to produce both respiratory and enteric disease in sheep. We isolated a virus (strain T94-0353) from the small intestine of a 3 week old kid with diarrhea and serous ocular and nasal discharge with the morphological and physiochemical characteristics of an adenovirus. Neutralization tests comparing the caprine adenovirus with the prototype ovine and bovine adenovirus serotypes and a previously isolated caprine adenovirus indicated that the caprine isolate is a new serotype and represents a new adenovirus species. This information is important for veterinary diagnosticians and if the virus is demonstrated to be widespread in the United States there may be a need to develop a vaccine.

Technical Abstract: A virus (T94-0353) isolated from the small intestine of a 3 week old kid with diarrhea and serous ocular and nasal discharge was identified as an adenovirus based on morphological and physiochemical characteristics. Neutralization tests and restriction endonuclease analysis comparing the caprine adenovirus with the prototype ovine and bovine adenovirus serotypes and a previously isolated caprine adenovirus indicated that the caprine isolate was antigenically different, produced a unique restriction pattern and represents a new adenovirus species.