Fruit and Vegetable Biomarker Study: Dietary Biomarker Development Center (DBDC) AIM 2
Who is conducting the study?
Carolyn M. Slupsky, Ph.D., UC Davis Professor and DBDC Program Director.
What is the purpose of this study?
We hope to identify biomarkers in the blood and urine that provide information about fruit and vegetable intake. We will be specifically investigating biomarkers for bananas, peaches, strawberries, tomatoes, green beans, and carrots.
Where is the study being conducted?
WHNRC, 430 West Health Sciences Drive, University of California, Davis, California, 95616
Who can participate in this study?
- Relatively healthy adults above the age of 18 with a BMI (body mass index) of 18.5 – 39.9
- People willing to eat bananas, peaches, strawberries, tomatoes, green beans, and carrots
- People willing to provide blood, urine, and stool samples
What would exclude me from participating in the study?
- Allergy or aversion to any provided test foods (includes animal products)
- Pregnancy or lactation
- Having a medical history that includes GI disorders, bariatric surgery, bleeding disorders that preclude blood draws, unstable cardiovascular disease, cancer under active or recent treatment, or recent hospitalization for heart attack, stroke, or heart failure
- Current use of certain prescription medications
- Recent significant weight change
What can I expect to happen during the study?
First, you will be screened for eligibility with a 15-20 minute telephone interview.
Second, if you meet our basic inclusion criteria you will come to the WHNRC for a screening visit so we can fully explain the study to you, get your consent to participate, and conduct a more in-depth assessment of your eligibility. This assessment will include measurements of body weight, height, heart rate, blood pressure, the assessment of veins for blood draws, and a blood draw. This visit will last about 40 - 60 minutes.
If you are determined to be eligible, you will be enrolled in the study. The study lasts ~10 days (over about 2 weeks). After the screening visit, there are approximately 6 more study visits during the study period, including three test days that last about 1-2 hours each.
In this study, we will ask you to participate in one of three randomly assigned groups. If you are assigned to the first group, you will be provided a diet high in the fruits and vegetables that we are testing. If you are assigned to the second group, you will be provided a diet that has the fruits and vegetables that we are testing, but in low amounts. If you are assigned to the third group, you will be provided a diet that does not contain fruits and vegetables. You will be given 9 days worth of food and beverages. We will ask you to only eat and drink the provided foods and beverages during the study period. In total, participants will provide 2-3 blood samples, 2-3 overnight urine samples, and 2 optional stool collections.
What is your compensation from this study?
You will receive $250 after completing all visits.If you are unable to complete the entire study, we will provide you with $150 for completing the dietary intervention and providing biological samples on visit 2, and an additional $100 if you are in one of the arms that receives the test fruits and vegetables, (Total: $250). If you are in the arm that receives no test fruits and vegetables, we will provide you with the full $250 after completing visit 2.
What should I do if I have questions or want to participate in the study?
Please contact our study line at 530-752-5177, press #1, and leave a message that you are interested in Aim 2 the Fruit and Vegetable Biomarker study. One of our study team members will contact you to let you know more about the study and answer questions.
Studypages - Study to Identify Markers of Fruit and Vegetable Intake (Aim 2)
