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ARS Home » Southeast Area » New Orleans, Louisiana » Southern Regional Research Center » Food and Feed Safety Research » People & Locations » Matthew Lebar
Matthew Lebar
Food and Feed Safety Research
Chemist

Phone: (504) 286-4321
Fax:

(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)

Projects
Development of Aflatoxin Resistant Corn Lines Using Omic Technologies
In-House Appropriated (D)
  Accession Number: 440095
Aflatoxin Control through Identification of Intrinsic and Extrinsic Factors Governing the Aspergillus Flavus-Corn Interaction
In-House Appropriated (D)
  Accession Number: 440096
Aspergillus flavus Genes, Metabolites, and Nutrients that Influence Development, Virulence, and Production of Regulated and Unregulated Mycotoxins
Non-Assistance Cooperative Agreement (S)
  Accession Number: 446627

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Investigating the impact of flavonoids on aspergillus flavus: Insights into cell wall damage and biofilms Reprint Icon - (Peer Reviewed Journal)
Castano-Duque, L.M., Lebar, M.D., Mack, B.M., Lohmar, J.M., Carter Wientjes, C.H. 2024. Investigating the impact of flavonoids on aspergillus flavus: Insights into cell wall damage and biofilms. The Journal of Fungi. 10(9). 665. https://doi.org/10.3390/jof10090665.
Divergent Aspergillus flavus corn population is composed of prolific conidium producers: implications for saprophytic disease cycle Reprint Icon - (Peer Reviewed Journal)
Sweany, R.R., Mack, B.M., Gebru, S.T., Mammel, M.K., Cary, J.W., Moore, G.G., Lebar, M.D., Carter Wientjes, C.H., Gilbert, M.K. 2024. Divergent Aspergillus flavus corn population is composed of prolific conidium producers: implications for saprophytic disease cycle. Mycologia. https://doi.org/10.1080/00275514.2024.2343645.
Combined omics approaches reveal distinct mechanisms of resistance and/or susceptibility in sugar beet double haploid genotypes at early stages of beet curly top virus infection Reprint Icon - (Peer Reviewed Journal)
Galewski, P.J., Majumdar, R., Lebar, M.D., Strausbaugh, C.A., Eujayl, I.A. 2023. Combined omics approaches reveal distinct mechanisms of resistance and/or susceptibility in sugar beet double haploid genotypes at early stages of beet curly top virus infection. International Journal of Molecular Sciences. 24(19). Article 15013. https://doi.org/10.3390/ijms241915013.
Vibrio gazogenes-dependent disruption of aflatoxin biosynthesis in Aspergillus flavus: the connection with endosomal uptake and hyphal morphogenesis Reprint Icon - (Peer Reviewed Journal)
Jesmin, R., Cary, J.W., Lebar, M.D., Majumdar, R., Gummadidala, P.M., Dias, T., Chandler, S., Basu, P., Decho, A.W., Keller, N.P., Chanda, A. 2023. Vibrio gazogenes-dependent disruption of aflatoxin biosynthesis in Aspergillus flavus: the connection with endosomal uptake and hyphal morphogenesis. Frontiers in Microbiology. 14:1208961. https://doi.org/10.3389/fmicb.2023.1208961.
Genes and genetic mechanisms contributing to fall armyworm resistance in maize Reprint Icon - (Peer Reviewed Journal)
Warburton, M.L., Woolfolk, S.W., Smith, J.S., Hawkins, L.K., Castano-Duque, L.M., Lebar, M.D., Williams, W.P. 2023. Genes and genetic mechanisms contributing to fall armyworm resistance in maize. The Plant Genome. 16(2):e20311. https://doi.org/10.1002/tpg2.20311.
Putative core transcription factors affecting virulence in Aspergillus flavus during infection of maize Reprint Icon - (Peer Reviewed Journal)
Gilbert, M.K., Mack, B.M., Lebar, M.D., Chang, P.-K., Gross, S.R., Sweany, R.R., Cary, J.W., Rajasekaran, K. 2023. Putative core transcription factors affecting virulence in Aspergillus flavus during infection of maize. The Journal of Fungi. 9(1):118. https://doi.org/10.3390/jof9010118.
Flavonoids modulate Aspergillus flavus proliferation and aflatoxin production Reprint Icon - (Peer Reviewed Journal)
Castano-Duque, L., Lebar, M.D., Carter-Wientjes, C., Ambrogio, D., Rajasekaran, K. 2022. Flavonoids modulate Aspergillus flavus proliferation and aflatoxin production. The Journal of Fungi. 8(1):1211. https://doi.org/10.3390/jof8111211.
Small NRPS-like enzymes in Aspergillus sections Flavi and Circumdati selectively form substituted pyrazinone metabolites Reprint Icon - (Peer Reviewed Journal)
Lebar, M.D., Mack, B.M., Carter Wientjes, C.H., Wei, Q., Mattison, C.P., Cary, J.W. 2022. Small NRPS-like enzymes in Aspergillus sections Flavi and Circumdati selectively form substituted pyrazinone metabolites. Frontiers in Fungal Biology. 3:1029195. https://doi.org/10.3389/ffunb.2022.1029195.
Cumulative effects of non-aflatoxigenic Aspergillus flavus volatile organic compounds to abate toxin production by mycotoxigenic aspergilli Reprint Icon - (Peer Reviewed Journal)
Moore, G.G., Lebar, M.D., Carter-Wientjes, C.H. 2022. Cumulative effects of non-aflatoxigenic Aspergillus flavus volatile organic compounds to abate toxin production by mycotoxigenic aspergilli. Toxins. 14:340. https://doi.org/10.3390/toxins14050340.
Development of sexual structures influences metabolomic and transcriptomic profiles in Aspergillus flavus - (Peer Reviewed Journal)
Luis, J.M., Carbone, I., Mack, B.M., Lebar, M.D., Cary, J.W., Gilbert, M.K., Bhatnagar, D., Carter-Wientjes, C.H., Payne, G.A., Moore, G.G., Ameen, Y.O., Ojiambo, P.S. 2022. Development of sexual structures influences metabolomic and transcriptomic profiles in Aspergillus flavus. Fungal Biology. 126:187-200.
Vibrio gazogenes inhibits aflatoxin production through downregulation of aflatoxin biosynthetic genes in Aspergillus flavus Reprint Icon - (Peer Reviewed Journal)
Kandel, S.L., Jesmin, R., Mack, B.M., Majumdar, R., Gilbert, M.K., Cary, J.W., Lebar, M.D., Gummadidala, P.M., Calvo, A.M., Rajasekaran, K., Chanda, A. 2022. Vibrio gazogenes inhibits aflatoxin production through downregulation of aflatoxin biosynthetic genes in Aspergillus flavus. PhytoFrontiers. 2(3):218-229. https://doi.org/10.1094/PHYTOFR-09-21-0067-R.
Genetic responses and aflatoxin inhibition during co-culture of aflatoxigenic and non-aflatoxigenic Aspergillus flavus Reprint Icon - (Peer Reviewed Journal)
Sweany, R.R., Mack, B.M., Moore, G.G., Gilbert, M.K., Cary, J.W., Lebar, M.D., Rajasekaran, K., Damann Jr, K.E. 2021. Genetic responses and aflatoxin inhibition during co-culture of aflatoxigenic and non-aflatoxigenic Aspergillus flavus. Toxins. 13:794. https://doi.org/10.3390/toxins13110794.
Flavonoids modulate the accumulation of toxins from Aspergillus flavus in maize kernels Reprint Icon - (Peer Reviewed Journal)
Castano-Duque, L.M., Gilbert, M.K., Mack, B.M., Lebar, M.D., Carter-Wientjes, C.H., Sickler, C.M., Cary, J.W., Rajasekaran, K. 2021. Flavonoids modulate the accumulation of toxins from Aspergillus flavus in maize kernels. Frontiers in Plant Science. 12:761446. https://doi.org/10.3389/fpls.2021.761446.
The potential role of fungal volatile organic compounds in Aspergillus flavus biocontrol efficacy Reprint Icon - (Peer Reviewed Journal)
Moore, G.G., Lebar, M.D., Carter-Wientjes, C.H., Gilbert, M.K. 2021. The potential role of fungal volatile organic compounds in Aspergillus flavus biocontrol efficacy. Biological Control. 160:104686. https://doi.org/10.1016/j.biocontrol.2021.104686.
Chemical repertoire and biosynthetic machinery of the Aspergillus flavus secondary metabolome: A review Reprint Icon - (Review Article)
Uka, V., Cary, J.W., Lebar, M.D., Puel, O., De Saeger, S., Diana Di Mavungu, J. 2020. Chemical repertoire and biosynthetic machinery of the Aspergillus flavus secondary metabolome: A review. Comprehensive Reviews in Food Science and Food Safety. 19(6):2797-2842. https://doi.org/10.1111/1541-4337.12638.
Characterization of morphological changes within stromata during sexual reproduction in Aspergillus flavus Reprint Icon - (Peer Reviewed Journal)
Luis, J.M., Carbone, I., Payne, G.A., Bhatnagar, D., Cary, J.W., Moore, G.G., Lebar, M.D., Wei, Q., Mack, B., Ojiambo, P.S. 2020. Characterization of morphological changes within stromata during sexual reproduction in Aspergillus flavus. Mycologia. 112(5):908-920. https://doi.org/10.1080/00275514.2020.1800361.
Biosynthesis of conidial and sclerotial pigments in Aspergillus species Reprint Icon - (Review Article)
Chang, P.-K., Cary, J.W., Lebar, M.D. 2020. Biosynthesis of conidial and sclerotial pigments in Aspergillus species. Applied Microbiology and Biotechnology. 104:2277-2286. https://doi.org/10.1007/s00253-020-10347-y.
rmtA-dependent transcriptome and its role in secondary metabolism, environmental stress, and virulence in Aspergillus flavus Reprint Icon - (Peer Reviewed Journal)
Satterlee, T., Entwistle, S., Yin, Y., Cary, J.W., Lebar, M.D., Losada, L., Calvo, A.M. 2019. rmtA-dependent transcriptome and its role in secondary metabolism, environmental stress, and virulence in Aspergillus flavus. G3, Genes/Genomes/Genetics. 9(12):4087-4096. https://doi.org/10.1534/g3.119.400777.
The secondary metabolism of Aspergillus flavus: small molecules with diverse biological function - (Abstract Only)
Contribution of maize polyamine and amino acid metabolism toward resistance against Aspergillus flavus infection and aflatoxin production Reprint Icon - (Peer Reviewed Journal)
Majumdar, R., Minocha, R., Lebar, M.D., Rajasekaran, K., Long, S., Carter-Wientjes, C.H., Minocha, S., Cary, J.W. 2019. Contribution of maize polyamine and amino acid metabolism toward resistance against Aspergillus flavus infection and aflatoxin production. Frontiers in Plant Science. 10:692. https://doi.org/10.3389/fpls.2019.00692.
Identification of a copper-transporting ATPase involved in biosynthesis of A. flavus conidial pigment Reprint Icon - (Peer Reviewed Journal)
Chang, P.-K., Scharfenstein, L.L., Mack, B.M., Wei, Q., Gilbert, M.K., Lebar, M.D., Cary, J.W. 2019. Identification of a copper-transporting ATPase involved in biosynthesis of A. flavus conidial pigment. Applied Microbiology and Biotechnology. 103:4889-4897. https://doi.org/10.1007/s00253-019-09820-0.
Targeting polyamine metabolism for control of fungal pathogenesis and increasing host resistance during the maize-Aspergillus flavus interaction - (Abstract Only)
The aspergillic acid biosynthetic gene cluster predicts neoaspergillic acid production in Aspergillus section Circumdati Reprint Icon - (Peer Reviewed Journal)
Lebar, M.D., Mack, B.M., Carter-Wientjes, C.H., Gilbert, M.K. 2019. The aspergillic acid biosynthetic gene cluster predicts neoaspergillic acid production in Aspergillus section Circumdati. World Mycotoxin Journal. 12(3):213-222. https://doi.org/10.3920/WMJ2018.2397.
Aspergillus flavus secondary metabolites and their roles in fungal development, survival and virulence - (Abstract Only)
Host-induced silencing of Aspergillus flavus genes to control preharvest aflatoxin contamination in maize - (Abstract Only)
The role of extrolites secreted by nonaflatoxigenic Aspergillus flavus in biocontrol efficacy Reprint Icon - (Peer Reviewed Journal)
Moore, G.G., Lebar, M.D., Carter-Wientjes, C.H. 2018. The role of extrolites secreted by nonaflatoxigenic Aspergillus flavus in biocontrol efficacy. Journal of Applied Microbiology. 126:1257-1264. https://doi.org/10.1111/jam.14175.
Contribution of maize polyamine and amino acid metabolism towards resistance against Aspergillus flavus infection and aflatoxin production - (Abstract Only)
Whole genome comparison of Aspergillus flavus L-morphotype strain NRRL 3357 (type) and S-morphotype strain AF70 Reprint Icon - (Peer Reviewed Journal)
Gilbert, M.K., Mack, B.M., Moore, G.G., Downey, D.L., Lebar, M.D., Joarder, V., Losada, L., Yu, J., Nierman, W.C., Bhatnagar, D. 2018. Whole genome comparison of Aspergillus flavus L-morphotype strain NRRL 3357 (type) and S-morphotype strain AF70. PLoS One. 13(7):e0199169. https://doi.org/10.1371/journal.pone.0199169.
Identification and functional analysis of the aspergillic acid gene cluster in Aspergillus flavus - (Peer Reviewed Journal)
Lebar, M.D., Cary, J.W., Majumdar, R., Carter-Wientjes, C.H., Mack, B.M., Wei, Q., Uka, V., De Saeger, S., Diana Di Mavungu, J. 2018. Identification and functional analysis of the aspergillic acid gene cluster in Aspergillus flavus. Fungal Genetics and Biology. 116:14-23.
Aspergillus flavus secondary metabolites: more than just aflatoxins Reprint Icon - (Review Article)
Cary, J.W., Gilbert, M.K., Lebar, M.D., Majumdar, R., Calvo, A.M. 2018. Aspergillus flavus secondary metabolites: more than just aflatoxins. Food Safety. 6(1):7-32. https://doi.org/10.14252/foodsafetyfscj.2017024.
RNA interference-based silencing of the alpha-amylase (amy1) gene in Aspergillus flavus decreases fungal growth and aflatoxin production in maize kernels Reprint Icon - (Peer Reviewed Journal)
Gilbert, M.K., Majumdar, R., Rajasekaran, K., Chen, Z.-Y., Wei, Q., Sickler, C.M., Lebar, M.D., Cary, J.W., Frame, B.R., Wang, K. 2018. RNA interference-based silencing of the alpha-amylase (amy1) gene in Aspergillus flavus decreases fungal growth and aflatoxin production in maize kernels. Planta. 247:1465–1473. https://doi.org/10.1007/s00425-018-2875-0.
The Aspergillus flavus spermidine synthase (spds) gene, is required for normal development, aflatoxin production, and pathogenesis during infection of maize kernels - (Peer Reviewed Journal)
Majumdar, R., Lebar, M.D., Mack, B.M., Minocha, R., Minocha, S., Carter-Wientjes, C.H., Sickler, C.M., Rajasekaran, K., Cary, J.W. 2018. The Aspergillus flavus spermidine synthase (spds) gene, is required for normal development, aflatoxin production, and pathogenesis during infection of maize kernels. Frontiers in Plant Science. 9:317. https://doi.org/10.3389/fpls.2018.00317.
Carbon dioxide mediates the response to temperature and water activity levels in Aspergillus flavus during infection of maize kernels Reprint Icon - (Peer Reviewed Journal)
Gilbert, M.K., Medina, A., Mack, B.M., Lebar, M.D., Rodriguez, A., Bhatnagar, D., Magan, N., Obrian, G., Payne, G. 2018. Carbon dioxide mediates the response to temperature and water activity levels in Aspergillus flavus during infection of maize kernels. Toxins. 10(1):5. https://doi.org/10.3390/toxins10010005.
The Aspergillus flavus homeobox gene, hbx1, is required for development and aflatoxin production Reprint Icon - (Peer Reviewed Journal)
Cary, J.W., Harris-Coward, P.Y., Scharfenstein, L.L., Mack, B.M., Chang, P.-K., Wei, Q., Lebar, M.D., Carter-Wientjes, C.H., Majumdar, R., Mitra, C., Banerjee, S., Chanda, A. 2017. The Aspergillus flavus homeobox gene, hbx1, is required for development and aflatoxin production. Toxins. 9(10):315. https://doi.org/10.3390/toxins9100315.
The pathogenesis-related maize seed (PRms) gene plays a role in resistance to Aspergillus flavus infection and aflatoxin contamination Reprint Icon - (Peer Reviewed Journal)
Majumdar, R., Rajasekaran, K., Sickler, C.M., Lebar, M.D., Musungu, B.M., Fakhoury, A.M., Payne, G.A., Geisler, M., Carter-Wientjes, C.H., Wei, Q., Bhatnagar, D., Cary, J.W. 2017. The pathogenesis-related maize seed (PRms) gene plays a role in resistance to Aspergillus flavus infection and aflatoxin contamination. Frontiers in Plant Science. 8:1758. https://doi.org/10.3389/fpls.2017.01758.
Effect of water activity, temperature, and carbon dioxide on the Aspergillus flavus transcriptome and aflatoxin B1 production - (Other)
Gilbert, M.K., Medina-Vaya, A., Mack, B.M., Lebar, M.D., Rodriguez, A., Bhatnagar, D., Magan, N., Obrian, G., Payne, G. 2017. Effect of water activity, temperature, and carbon dioxide on the Aspergillus flavus transcriptome and aflatoxin B1 production. National Center for Biotechnology Information (NCBI). Accession: PRJNA380582.