Erik R Gertz
Obesity and Metabolism Research
Chemist
Phone: (530) 754-5779
Fax: (530) 752-5271
(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
Publications
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Integrative analysis of hepatic transcriptional profiles reveals genetic regulation of atherosclerosis in hyperlipidemic Diversity Outbred-F1 mice
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Kim, M., Huda, N., Evans, L.W., Que, E., Gertz, E.R., Maeda-Smithies, N., Bennett, B.J. 2023. Integrative analysis of hepatic transcriptional profiles reveals genetic regulation of atherosclerosis in hyperlipidemic Diversity Outbred-F1 mice. Scientific Reports. 13. Article 9475. https://doi.org/10.1038/s41598-023-35917-8.
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Trimethylamine N-Oxide response to a mixed macronutrient tolerance test in a cohort of United States adults
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James, K.L., Gertz, E.R., Kirschke-Schneide, C.P., Allayee, H., Huang, L., Kable, M.E., Newman, J.W., Stephensen, C.B., Bennett, B.J. 2023. Trimethylamine N-Oxide response to a mixed macronutrient tolerance test in a cohort of United States adults. International Journal of Molecular Sciences. 24(3). Article 2074. https://doi.org/10.3390/ijms24032074.
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Altered macronutrient composition and genetics influence the complex transcriptional network associated with adiposity in the Collaborative Cross
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Yam, P., VerHague, M., Albright, J., Gertz, E.R., Manuel-de-Villena, F., Bennett, B.J. 2022. Altered macronutrient composition and genetics influence the complex transcriptional network associated with adiposity in the Collaborative Cross. Genes and Nutrition. 17. Article 13. https://doi.org/10.1186/s12263-022-00714-x.
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Diet, fecal microbiome, and trimethylamine N-oxide in a cohort of metabolically healthy United States adults
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James, K.L., Gertz, E.R., Cervantes, E., Bonnel, E., Stephensen, C.B., Kable, M.E., Bennett, B.J. 2022. Diet, fecal microbiome, and trimethylamine N-oxide in a cohort of metabolically healthy United States adults. Nutrients. 14(7). Article 1376. https://doi.org/10.3390/nu14071376.
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Adopting a Mediterranean-style eating pattern with low, but not moderate, unprocessed, lean red meat intake reduces fasting serum trimethylamine N-oxide (TMAO) in adults who are overweight or obese
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Krishnan, S., O'Connor, L., Wang, Y., Gertz, E.R., Campbell, W.W., Bennett, B.J. 2021. Adopting a Mediterranean-style eating pattern with low, but not moderate, unprocessed, lean red meat intake reduces fasting serum trimethylamine N-oxide (TMAO) in adults who are overweight or obese. British Journal of Nutrition. https://doi.org/10.1017/S0007114521004694.
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Effects of a diet based on the Dietary Guidelines on vascular health and TMAO in women with cardiometabolic risk factors
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Krishnan, S., Gertz, E.R., Adams, S.H., Newman, J.W., Pedersen, T.L., Keim, N.L., Bennett, B.J. 2021. Effects of a diet based on the Dietary Guidelines on vascular health and TMAO in women with cardiometabolic risk factors. Nutrition Metabolism and Cardiovascular Disease. 32(1):210-219. https://doi.org/10.1016/j.numecd.2021.09.013.
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Genetic background shapes phenotypic response to diet for adiposity in the Collaborative Cross
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Yam, P., Albright, J., Verhague, M., Gertz, E.R., Pardo-Manuel De Vill, V., Bennett, B.J. 2021. Genetic background shapes phenotypic response to diet for adiposity in the Collaborative Cross. Frontiers in Genetics. 11. Article 615012. https://doi.org/10.3389/fgene.2020.615012.
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Weight loss, but not dairy composition of diet, moderately affects satiety and postprandial gut hormone patterns in adults
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Krishnan, S., Adams, S., Witbracht, M.G., Woodhouse, L.R., Piccolo, B.D., Thomas, A.P., Souza, E.C., Horn, W.F., Gertz, E.R., Van Loan, M.D., Keim, N.L. 2020. Weight loss, but not dairy composition of diet, moderately affects satiety and postprandial gut hormone patterns in adults. Journal of Nutrition. 151(1):245-254. https://doi.org/10.1093/jn/nxaa327.
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Determining the genetic regulation of trimethylamine N-oxide in female diversity outbred mice
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High-fat diet–induced colonocyte dysfunction escalates microbiota-derived trimethylamine N-oxide
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Yoo, W., Zieba, J.K., Foegeding, N.J., Torres, T.P., Shelton, C.D., Shealy, N.G., Byndloss, A.J., Cevallos, S.A., Gertz, E.R., Tiffany, C.R., Thomas, J., Litvak, Y., Nguyen, H., Olsan, E.E., Bennett, B.J., Rathmell, J.C., Major, A.S., Baumler, A.J., Byndloss, M.X. 2021. High-fat diet–induced colonocyte dysfunction escalates microbiota-derived trimethylamine N-oxide. Science. 373(6556):813-818. https://doi.org/10.1126/science.aba3683.
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Trimethylamine-N-oxide (TMAO) is not associated with average daily inatke of red meat or TMAO precursor foods in a generally healthy population
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Kristen, J., Gertz, E.R., Stephensen, C.B., Bennett, B.J. 2020. Trimethylamine-N-oxide (TMAO) is not associated with average daily inatke of red meat or TMAO precursor foods in a generally healthy population. Current Developments in Nutrition. 4(2):37. https://doi.org/10.1093/cdn/nzaa040_037.
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Sexual dimorphism of atherosclerosis by gut microbiome in a hyperlipidemic diversity outbred F1 mouse population
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Kim, M., Huda, N., Que, E.S., Gertz, E.R., Bennett, B.J. 2020. Sexual dimorphism of atherosclerosis by gut microbiome in a hyperlipidemic diversity outbred F1 mouse population. Current Developments in Nutrition. 4(2):1569. https://doi.org/10.1093/cdn/nzaa062_026.
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A Mediterranean-style eating pattern lower in lean red meat reduced plasma trimethylamine N-oxide in adults classified as overweight or obese
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Gertz, E.R., Wang, Y., O'Connor, L., Campbell, W.W., Bennett, B.J. 2019. A Mediterranean-style eating pattern lower in lean red meat reduced plasma trimethylamine N-oxide in adults classified as overweight or obese. Meeting Abstract. 3(1). https://doi.org/10.1093/cdn/nzz044.P08-030-19.
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A randomized controlled-feeding trial based on the Dietary Guidelines for Americans does not affect plasma trimethylamine N-oxide levels in women
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Gertz, E.R., Krishnan, S., Peerson, J.M., Adams, S.H., Laugero, K.D., Newman, J.W., Keim, N.L., Bennett, B.J. 2019. A randomized controlled-feeding trial based on the Dietary Guidelines for Americans does not affect plasma trimethylamine N-oxide levels in women. Meeting Abstract. (3)1. https://doi.org/10.1093/cdn/nzz044.P08-031-19.
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Circulating 25(OH)D concentrations in overweight and obese adults is explained by sun exposure, skin reflectance, and body composition
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Piccolo, B.D., Hall, L.M., Stephensen, C.B., Gertz, E.R., Van Loan, M.D. 2019. Circulating 25(OH)D concentrations in overweight and obese adults is explained by sun exposure, skin reflectance, and body composition. Current Developments in Nutrition. doi.org/10.1093/cdn/nzz065.
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Sexual dimorphism of atherosclerosis and plasma lipids: Analysis of complex traits in a diversity outbred F1 mouse population
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Sexual dimorphism of atherosclerosis and plasma lipids: Analysis of complex traits in a diversity outbred F1 mouse population. Meeting Abstract. (39)1. https://doi.org/10.1161/atvb.39.suppl_1.154.
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The effects of a lipid-based nutrient supplement and antiretroviral therapy in a randomized controlled trial on iron, copper, and zinc in milk from HIV+ Malawian mothers and associations with maternal and infant biomarkers
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Hampel, D., Shahab-Ferdows, S., Gertz, E.R., Flax, V.L., Adair, L.S., Bentley, M.E., Jamieson, D.J., Tegha, G., Chasela, C.S., Kamwendo, D., Van Der Horst, C.M., Allen, L.H. 2017. The effects of a lipid-based nutrient supplement and antiretroviral therapy in a randomized controlled trial on iron, copper, and zinc in milk from HIV+ Malawian mothers and associations with maternal and infant biomarkers. Maternal and Child Nutrition. 14(2):e12503. https://doi.org/10.1111/mcn.12503.
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The role of a dairy fraction rich in milk fat globule membrane in the suppression of postprandial inflammatory markers and bone turnover in obese and overweight adults: an exploratory study.
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Rogers, T.S., Demmer, E., Rivera, N., Gertz, E.R., German, B.J., Smilowitz, J.T., Zivkovic, A.M., Van Loan, M.D. 2017. The role of a dairy fraction rich in milk fat globule membrane in the suppression of postprandial inflammatory markers and bone turnover in obese and overweight adults: an exploratory study.. Nutrition and Metabolism. 14: 001-009 DOI: 10.1186/s12986-017-0189-z..
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Contribution of magnesium and micronutrients to bone metabolism in post menopausal women consuming a fixed amount of calcium and vitamin d: an exploratory study
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Richarson, C.E., Rogers, T.S., Demmer, E., Garrod, M.G., Gertz, E.R., Van Loan, M.D. 2017. Contribution of magnesium and micronutrients to bone metabolism in post menopausal women consuming a fixed amount of calcium and vitamin d: an exploratory study . Journal of Nutrition and Food Sciences. 2:001-008.
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Is bone equally responsive to calcium and vitamins D intake from food vs. supplements? Use of 41Ca tracer kinetic model
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Rogers, T.S., Demmer, E., Richardson, C., Gertz, E.R., Buchholz, B., Hillegonds, D., Garrod, M.G., Van Loan, M.D. 2016. Is bone equally responsive to calcium and vitamins D intake from food vs. supplements? Use of 41Ca tracer kinetic model. Bone Reports. 5:117-123. doi: 10.1016/j.bonr.2016.05.001.
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Addition of a dairy rich milk fat globule membrane to a high-saturated fat meal reduces the postprandial insulinaemic and inflammatory response in overweight and obese adults
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Demmer, E., Van Loan, M.D., Rivera, N., Rogers, T.S., Gertz, E.R., German, J., Smilowitz, J.T., Zivkovic, A.M. 2016. Addition of a dairy rich milk fat globule membrane to a high-saturated fat meal reduces the postprandial insulinaemic and inflammatory response in overweight and obese adults. Journal of Nutritional Science. 5(e14):1-11. doi: 10.1017/jns.2015.42.
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Consumption of high-fat meal containing cheese compared to a vegan alternative lowers postprandial C-reactive protein in overweight and obese individuals with metabolic abnormalities: a randomised controlled crossover study
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Demmer, E., Van Loan, M.D., Rivera, N., Rogers, T.S., Gertz, E.R., German, J.B., Zivkovic, A.M., Smilowitz, J.T. 2016. Consumption of high-fat meal containing cheese compared to a vegan alternative lowers postprandial C-reactive protein in overweight and obese individuals with metabolic abnormalities: a randomised controlled crossover study. Nutritional Science. 5(e9):1-12. doi: 10.1017/jns.2015.40.
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Consumption of high-fat meal containing cheese compared with vegan alternative lowers postprandial C-reactive protein in overweight and obese individuals with metabolic abnormalities: a randomized controlled cross-over study
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Red palm oil-supplemented and biofortified gari on the carotenoid and retinyl palmitate concentrations of triacylglycerol-rich plasma of women
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Zhu, C.H., Cai, Y., Gertz, E.R., Lafrano, M.R., Burnett, D., Burri, B.J. 2015. Red palm oil-supplemented and biofortified gari on the carotenoid and retinyl palmitate concentrations of triacylglycerol-rich plasma of women. Nutrition Research. DOI:10.1016/j.nutres.2015.08.003.
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Habitual physical activity and plasma metabolomics patterns distinguish individuals with low- versus high-weight loss during controlled energy restriction
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Piccolo, B., Van Loan, M.D., Gertz, E.R., Woodhouse, L.R., Souza, E., Gustafson, M.B., Campbell, C., Fiehn, O., Keim, N.L., Adams, S.H., Newman, J.W. 2015. Habitual physical activity and plasma metabolomics patterns distinguish individuals with low- versus high-weight loss during controlled energy restriction. Journal of Nutrition. 145(4):681-690. doi: 10.3945/jn.114.201574.
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Serum biomarkers of bone metabolism in castration resistant prostate cancer patients with skeletal metastases
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Lara, P.N., Ely, B., Quinn, D.L., Mack, P.C., Tangen, C.M., Gertz, E.R., Twardowski, P.W., Goldkorn, A., Hussain, M., Vogelzang, N.J., Thompson, I.M., Van Loan, M.D. 2014. Serum biomarkers of bone metabolism in castration resistant prostate cancer patients with skeletal metastases. Journal of the National Cancer Institute. 106(4):1-9. DOI: 10.1093/jnci/dju013.
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Association between subcutaneous white adipose tissue and serum 25-hydroxyvitamin D in overweight and obese adults
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Piccolo, B.D., Dolnikowski, G., Seyoum, E., Thomas, A., Gertz, E.R., Souza, E.C., Keim, N.L., Adams, S.H., Newman, J.W., Woodhouse, L.R., Van Loan, M.D. 2013. Association between subcutaneous white adipose tissue and serum 25-hydroxyvitamin D in overweight and obese adults. American Journal of Clinical Nutrition. 5(9), 3352-3366. DOI:10.3390/nu5093352.
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Association between vitamin D metabolites in fat tissue and serum 25-hydroxy vitamin D in overweight and obese adults
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Piccolo, B.D., Gertz, E.R., Thomas, A.P., Keim, N.L., Adams, S.H., Seyoum, E., Dolnikowski, G., Van Loan, M.D. 2012. Association between vitamin D metabolites in fat tissue and serum 25-hydroxy vitamin D in overweight and obese adults. Journal of Federation of American Societies for Experimental Biology. 386.4.
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Evidence of associations between feto-maternal vitamin D status, cord parathyroid hormone and bone-specific alkaline phosphatase, and newborn whole body bone mineral content
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Dror, D.K., King, J.C., Fung, E.B., Van Loan, M.D., Gertz, E.R., Allen, L.H. 2012. Evidence of associations between feto-maternal vitamin D status, cord parathyroid hormone and bone-specific alkaline phosphatase, and newborn whole body bone mineral content. Nutrients. 4:68-77.
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Dairy foods in a moderate energy restricted diet do not enhance central fat, weight & intra-abdominal adipose tissue loss or reduce adipocyte size & inflammatory markers in overweight & obese adults; Controlled feeding study
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Van Loan, M.D., Keim, N.L., Adams, S.H., Souza, E., Woodhouse, L.R., Thomas, A., Witbracht, M., Gertz, E.R., Piccolo, B., Brenner, A.R., Spurlock, M. 2011. Dairy foods in a moderate energy restricted diet do not enhance central fat, weight & intra-abdominal adipose tissue loss or reduce adipocyte size & inflammatory markers in overweight & obese adults; Controlled feeding study. Journal of Obesity. 10.1155/2011/989657.
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Soy Isoflavones for Reducing Bone Loss (SIRBL) Study: Randomized Three Year Intervention in Postmenopausal Women
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Alekel, D.L., Van Loan, M.D., Koehler, K.J., Hanson, L.N., Stewart, J.W., Hanson, K.B., Genschel, U., Gertz, E.R., Kurzer, M.S., Peterson, C.T., Beer, B. 2009. Soy Isoflavones for Reducing Bone Loss (SIRBL) Study: Randomized Three Year Intervention in Postmenopausal Women. American Society for Bone and Mineral Research. 91(1):218-30.
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Serum 25-hydroxyvitamin D is related to indicators of overall physical fitness in healthy postmenopausal women
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Stewart, J.W., Alekel, D.L., Ritland, L.M., Van Loan, M.D., Gertz, E.R., Genschel, U. 2009. Serum 25-hydroxyvitamin D is related to indicators of overall physical fitness in healthy postmenopausal women. Menopause. 16:1093-1101.
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Znt7 (Slc30a7)-DEFICIENT MICE DISPLAY REDUCED BODY ZINC STATUS AND BODY FAT ACCUMULATION
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Huang, L., Yu, Y., Kirschke, C.P., Gertz, E.R., Kent K.C., L. 2008. Znt7 (Slc30a7)-Deficient Mice Display Rreduced Body ZincC Status and Body Fat Accumulation. Journal of Biological Chemistry. 282,51:37053-37063, 2007.
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PROTOCOL FOR ASSESSING BONE HEALTH IN HUMANS BY TRACING LONG-LIVED 41CA ISOTOPE IN URINE, SERUM, AND SALIVA SAMPLES
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Lin, Y.M., Hillegonds, D.J., Gertz, E.R., Van Loan, M.D., Vogel, J.S. 2004. PROTOCOL FOR ASSESSING BONE HEALTH IN HUMANS BY TRACING LONG-LIVED 41CA ISOTOPE IN URINE, SERUM, AND SALIVA SAMPLES. Analytical Chemistry. 332:193-195.
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