Skip to main content
ARS Home » Southeast Area » Oxford, Mississippi » Natural Products Utilization Research » People & Locations » Joanna Bajsa-Hirschel
Joanna Bajsa-Hirschel
Natural Products Utilization Research
Research Plant Physiologist

Phone: (662) 915-1549
Fax: (662) 915-1549

(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)

Projects
Novel Weed Management Tools from Natural Product-Based Discoveries
In-House Appropriated (D)
  Accession Number: 439382
Genetics Approaches to Identify the Modes of Action of Phytotoxins
Non-Assistance Cooperative Agreement (S)
  Accession Number: 444169

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Bioactive Secondary Metabolites from Curvularia spp.: Natural Alternatives for Pest Management in Agriculture - (Peer Reviewed Journal)
Characterization of the Phytotoxic Potential of Seven Copaifera spp. Essential Oils: Analyzing Active Compounds through Gas Chromatography–Mass Spectrometry Molecular Networking Reprint Icon - (Peer Reviewed Journal)
Ribeiro, V.P., Bajsa Hirschel, J.N., Bastos, J., Reichley, A.C., Duke, S.O., Meepagala, K.M. 2024. Characterization of the Phytotoxic Potential of Seven Copaifera spp. Essential Oils: Analyzing Active Compounds through Gas Chromatography–Mass Spectrometry Molecular Networking. Journal of Agricultural and Food Chemistry. 72:18528-18536. https://doi.org/10.1021/acs.jafc.4c04586.
Transcriptome and physiological analyses reveal the response of Arabidopsis thaliana to poly(aspartic acid) Reprint Icon - (Peer Reviewed Journal)
Machingura, M.C., Glover, S., Settles, A., Pan, Z., Bajsa Hirschel, J.N., Chitiyo, G., Weiland, M.H. 2024. Transcriptome and physiological analyses reveal the response of Arabidopsis thaliana to poly(aspartic acid). Plant Stress. 12:1-14. https://doi.org/10.1016/j.stress.2024.100478.
Menthalactone from Mentha piperita L., a Monocot-Selective Bioherbicide Reprint Icon - (Peer Reviewed Journal)
Soltani, A., Ospanov, M., Ibrahim, Z.M., Bajsa Hirschel, J.N., Cantrell, C.L., Cizdziel, J.V., Khan, I.A., Ibrahim, M.A. 2024. Menthalactone from Mentha piperita L., a Monocot-Selective Bioherbicide. International Journal of Plant Biology. 15:293-303. https://doi.org/10.3390/ijpb15020025.
Novel pyrazole acyl(thio)urea derivatives containing a biphenyl scaffold as potential succinate dehydrogenase inhibitors: Design, synthesis, fungicidal activity and SAR Reprint Icon - (Peer Reviewed Journal)
Sun, N., Min, L., Sun, Z., Zhai, Z., Bajsa Hirschel, J.N., Wei, Z., Hua, X., Cantrell, C.L., Xu, H., Duke, S.O., Liu, X. 2024. Novel pyrazole acyl(thio)urea derivatives containing a biphenyl scaffold as potential succinate dehydrogenase inhibitors: Design, synthesis, fungicidal activity and SAR. Journal of Agricultural and Food Chemistry. 72:2512-2525. https://doi.org/10.1021/acs.jafc.3c07735.
Antifungal and Phytotoxic activities of isolated compounds from Helietta parvifolia stems Reprint Icon - (Peer Reviewed Journal)
Ribeiro, V., Bajsa Hirschel, J.N., Tamang, P., Meepagala, K.M., Duke, S. 2023. Antifungal and phytotoxic activities of isolated compounds from Helietta parvifolia stems. Molecules. 28(23):7930. https://doi.org/10.3390/molecules28237930.
Molecular targets of herbicides and fungicides – are there useful overlaps for fungicide discovery? Reprint Icon - (Peer Reviewed Journal)
Duke, S.O., Pan, Z., Bajsa-Hirschel, J.N., Tamang, P., Hammerschmidt, R., Lorsbach, B.A, and Sparks, T.C. 2023. Molecular targets of herbicides and fungicides - are there useful overlaps for fungicide discovery? J. Agric. Food Chem. 71:20532-20548. https://doi.org/10.1021/acs.jafc.3c07166
Bioactive metabolites produced by fungi present in Antarctic, Arctic and alpine ecosystems Reprint Icon - (Book / Chapter)
Gonçalves, V.N., Carvalho, C.R., Martins, L.M., Barreto, D.L., Queiroz, S.C., Tamang, P., Bajsa Hirschel, J.N., Cantrell, C.L., Duke, S.O., Rosa, L.H. 2024. Bioactive metabolites produced by fungi present in Antarctic, Arctic and alpine ecosystems. In: Abdel-Azeem, A.M., Yadav, A.N., Yadav, N., Sharma, M., editors. Bioactive Metabolites from Fungi in Pharmaceutical Research and Development: Prospects & Avenues. p. 537-563. https://doi.org/10.1007/978-981-99-5696-8_17.
Synthesis, herbicidal activity and in silico analysis of novel pyrido[2,3-d]pyrimidine compounds Reprint Icon - (Peer Reviewed Journal)
Liang, W., Wang, Q., Min, L., Han, L., Cantrell, C.L., Bajsa Hirschel, J.N., Duke, S.0., Ye, P., Liu, X. 2023. Synthesis, herbicidal activity and in silico analysis of novel pyrido[2,3-d]pyrimidine compounds. Molecules. https://doi.org/10.3390/molecules28217363.
Synthesis, Herbicidal Activity, and Structure-Activity Relationships of O-Alkyl Analogues of Khellin and Visnagin Reprint Icon - (Peer Reviewed Journal)
Cantrell, C.L., Travaini, M., Bajsa Hirschel, J.N., Svendsen, L.D., Reichley, A.C., Sosa, G.M., Kim, S., Tamang, P., Meepagala, K.M., Duke, S.O. 2023. Synthesis, Herbicidal Activity, and Structure-Activity Relationships of O-Alkyl Analogues of Khellin and Visnagin. Journal of Agriculture and Food Chemistry. 71:14593-14603. https://doi.org/10.1021/acs.jafc.3c03254.
Agricultural Research Service weed science research: past, present, and future Reprint Icon - (Review Article)
Young, S.L., Anderson, J.V., Baerson, S.R., Bajsa Hirschel, J.N., Blumenthal, D.M., Boyd, C.S., Boyette, C.D., Brennan, E.B., Cantrell, C.L., Chao, W.S., Chee Sanford, J.C., Clements, D.D., Dray Jr, F.A., Duke, S.O., Porter, K.M., Fletcher, R.S., Fulcher, M.R., Gaskin, J., Grewell, B.J., Hamerlynck, E.P., Hoagland, R.E., Horvath, D.P., Law, E.P., Madsen, J., Martin, D.E., Mattox, C.M., Mirsky, S.B., Molin, W.T., Moran, P.J., Mueller, R.C., Nandula, V.K., Newingham, B.A., Pan, Z., Porensky, L.M., Pratt, P.D., Price, A.J., Rector, B.G., Reddy, K.N., Sheley, R.L., Smith, L., Smith, M., Snyder, K.A., Tancos, M.A., West, N.M., Wheeler, G.S., Williams, M., Wolf, J.E., Wonkka, C.L., Wright, A.A., Xi, J., Ziska, L.H. 2023. Agricultural Research Service weed science research: past, present, and future. Weed Science. 71(4):312-327. https://doi.org/10.1017/wsc.2023.31.
The Chlamydomonas reinhardtii chloroplast envelope protein LCIA transports bicarbonate in planta Reprint Icon - (Peer Reviewed Journal)
Förster, B., Rourke, L., Weerasooriya, H.N., Pabuayon, I.C., Au, E., Bala, S., Bajsa Hirschel, J.N., Kaines, S., Kasili, R., Laplace, L., Machingura, M.C., Massey, B., Rosati, V.C., Stuart-Williams, H., Badger, M.R., Price, G., Moroney, J.V. 2023. The Chlamydomonas reinhardtii chloroplast envelope protein LCIA transports bicarbonate in planta. Journal of Experimental Botany. https://doi.org/10.1093/jxb/erad116.
Synthesis and pesticidal activity of new niacinamide derivatives containing a flexible, chiral chain Reprint Icon - (Peer Reviewed Journal)
Wei, Z., Wang, Q., Min, L., Bajsa Hirschel, J.N., Cantrell, C.L., Han, L., Tan, C., Weng, J., Liu, X., Duke, S.O. 2022. Synthesis and pesticidal activity of new niacinamide derivatives containing a flexible, chiral chain. Molecules. https://doi.org/10.3390/molecules28010047.
Spliceostatin C, a component of a microbial bioherbicide, is a potent phytotoxin that inhibits the spliceosome Reprint Icon - (Peer Reviewed Journal)
Bajsa Hirschel, J.N., Pan, Z., Padney, P., Asolkar, R., Gopal Chittiboyina, A., Boddy, L., Machingura, M., Duke, S.O. 2023. Spliceostatin C, a component of a microbial bioherbicide, is a potent phytotoxin that inhibits the spliceosome. Frontiers in Plant Science. https://doi.org/10.3389/fpls.2022.1012939.
Synthesis and pesticidal activity of new 1,3,4-oxadiazole thioether compounds containing a trifluoro-methylpyrazoyl moiety Reprint Icon - (Peer Reviewed Journal)
Shi, H., Zhai, Z., Min, L., Han, L., Sun, N., Cantrell, C.L., Bajsa Hirschel, J.N., Duke, S.O., Liu, X. 2022. Synthesis and pesticidal activity of new 1,3,4-oxadiazole thioether compounds containing a trifluoro-methylpyrazoyl moiety. Research on Chemical Intermediates. https://doi.org/10.1007/s11164-022-04839-x.
Synthesis, crystal structure, herbicidal activity and mode of action of new cyclopropane-1,1-dicarboxylic acid analogues Reprint Icon - (Peer Reviewed Journal)
Min, L., Shen, Z., Bajsa Hirschel, J.N., Cantrell, C.L., Han, L., Hua, X., Liu, X., Duke, S.O. 2022. Synthesis, crystal structure, herbicidal activity and mode of action of new cyclopropane-1,1-dicarboxylic acid analogues. Pesticide Biochemistry and Physiology. https://doi.org/10.1016/j.pestbp.2022.105228.
Evaluation of the phytotoxic and antifungal activity of C17-sesquiterpenoids as potential biopesticides Reprint Icon - (Peer Reviewed Journal)
Cárdenas, D.M., Bajsa Hirschel, J.N., Cantrell, C.L., Rial, C., Varela, R.M., Molinillo, J.G., Macías, F.A. 2022. Evaluation of the phytotoxic and antifungal activity of C17-sesquiterpenoids as potential biopesticides. Pest Management Science. https://doi.org/10.1002/ps.7042.
Novel dioxolane ring compounds for the management of phytopathogen diseases as ergosterol biosynthesis inhibitors: synthesis, biological activities and molecular docking Reprint Icon - (Peer Reviewed Journal)
Min, L., Wang, H., Bajsa Hirschel, J.N., Yu, C., Wang, B., Yao, M., Han, L., Cantrell, C.L., Duke, S.O., Sun, N., Liu, X. 2022. Novel dioxolane ring compounds for the management of phytopathogen diseases as ergosterol biosynthesis inhibitors: synthesis, biological activities and molecular docking. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/acs.jafc.2c00541.
Differential gene expression patterns in Sorghum bicolor genotypes in response to high vapor pressure deficit Reprint Icon - (Peer Reviewed Journal)
Rajvi, D., Rodriguez, A., Bajsa Hirschel, J.N., Pan, Z., Machingura, M.C. 2021. Differential gene expression patterns in Sorghum bicolor genotypes in response to high vapor pressure deficit. Journal of Crop Improvement. https://doi.org/10.1080/15427528.2021.2009077.
The potential future roles of natural compounds and microbial bioherbicides in weed management in crops Reprint Icon - (Peer Reviewed Journal)
Duke, S.O., Pan, Z., Bajsa Hirschel, J.N., Boyette, C.D. 2022. The potential future roles of natural compounds and microbial bioherbicides in weed management in crops. Advances in Weed Science. 40(spe1):e020210054. https://doi.org/10.51694/AdvWeedSci/2022;40:seventy-five003.
Synthesis, crystal structure, herbicidal activity, and SAR study of Novel N-(Arylmethoxy)-2-chloronicotinamides derived from nicotinic acid Reprint Icon - (Peer Reviewed Journal)
Yu, C., Wang, Q., Min, L., Bajsa Hirschel, J.N., Hua, X., Cantrell, C.L., Duke, S., Liu, X. 2021. Synthesis, crystal structure, herbicidal activity, and SAR study of Novel N-(Arylmethoxy)-2-chloronicotinamides derived from nicotinic acid. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/acs.jafc.0c07538.
In vivo assembly of sorgoleone biosynthetic pathway and its impact on agroinfiltrated leaves of Nicotiana benthamiana - (Peer Reviewed Journal)
Pan, Z., Bajsa Hirschel, J.N., Vaughn, J.N., Rimando, A.M., Baerson, S.R., Duke, S.O. 2021. In vivo assembly of sorgoleone biosynthetic pathway and its impact on agroinfiltrated leaves of Nicotiana benthamiana. New Phytologist. 230:683-697.
Proving the mode of action of phytotoxic phytochemicals Reprint Icon - (Peer Reviewed Journal)
Duke, S., Pan, Z., Bajsa Hirschel, J.N. 2020. Proving the mode of action of phytotoxic phytochemicals. Plants. https://www.doi.org/10.3390/plants9121756.
Synthesis of pyranopyrans related to diplopyrone and evaluation as antibacterials and herbicides Reprint Icon - (Peer Reviewed Journal)
Roireau, J.H., Rosano, R.J., Chen, T., Bajsa Hirschel, J.N., Schrader, K.K., Duke, S.O., Wykoff, D., Giuliano, R.M. 2020. Synthesis of pyranopyrans related to diplopyrone and evaluation as antibacterials and herbicides. Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/acs.jafc.0c02564.
Synthesis and pesticidal activities of new Quinoxalines Reprint Icon - (Peer Reviewed Journal)
Liu, X., Yu, W., Min, L., Wedge, D., Tan, C., Weng, J., Wu, H., Cantrell, C.L., Bajsa Hirschel, J.N., Hua, X., Duke, S.O. 2020. Synthesis and pesticidal activities of new Quinoxalines. Journal of Agricultural and Food Chemistry. 68:7324-7332. https://doi.org/10.1021/acs.jafc.0c01042.
Secondary metabolites of Thymelaea hirsuta, a plant collected from the Sicilian Island of Lampedusa Reprint Icon - (Peer Reviewed Journal)
Nocera, P., Bajsa Hirschel, J.N., Masi, M., Ross, S.A., Cantrell, C.L., Duke, S.O., Surico, G., Evidente, A. 2020. Secondary metabolites of Thymelaea hirsuta, a plant collected from the Sicilian Island of Lampedusa. Natural Product Research. https://doi.org/10.1080/14786419.2020.1752212.
The contribution of Romidepsin to the herbicidal activity of Burkholderia rinojensis biopesticide Reprint Icon - (Peer Reviewed Journal)
Owens, D.K., Bajsa Hirschel, J.N., Duke, S.O., Carbonari, C.A., Gomes, G.L., Asolkar, R., Boddy, L., Dayan, F.E. 2020. The contribution of Romidepsin to the herbicidal activity of Burkholderia rinojensis biopesticide. Journal of Natural Products. 83(4):843-851. https://doi.org/10.1021/acs.jnatprod.9b00405.
Rice momilactone gene cluster: Transcriptional response to barnyard grass (Echinochloa crus-galli) Reprint Icon - (Peer Reviewed Journal)
Bajsa Hirschel, J.N., Pan, Z., Duke, S.O. 2020. Rice momilactone gene cluster: Transcriptional response to Barnyard grass (Echinochloa crus-galli). Molecular Biology Reports. 47:1507-1512. https://doi.org/10.1007/s11033-019-05205-8.
Transcriptome responses to the phytotoxin t-Chalcone in Arabidopsis thaliana L. Reprint Icon - (Peer Reviewed Journal)
Diaz-Tielas, C., Grana, E., Sanchez-Moreiras, A.M., Reigosa, M.J., Vaughn, J.N., Pan, Z., Bajsa Hirschel, J.N., Duke, S.O. 2019. Transcriptome responses to the phytotoxin t-Chalcone in Arabidopsis thaliana L. Pest Management Science. https://doi.org/10.1002/ps.5405.
Use of omics methods to determine the mode of action of natural phytotoxins - (Book / Chapter)
Duke, S.O., Pan, Z., Bajsa Hirschel, J.N., Sanchez-Moreiras, A.M., Vaughn, J.N. 2018. Use of omics methods to determine the mode of action of natural phytotoxins. American Chemical Society Symposium Series. 1294:33-46.
Validation of serine-threonine protein phosphatase as the herbicide target site of endothall - (Peer Reviewed Journal)
Bajsa, J.N., Pan, Z., Dayan, F.E., Owens, D.K., Duke, S.O. 2012. Validation of serine-threonine protein phosphatase as the herbicide target site of endothall. Journal of Pesticide Biochemistry and Physiology. 102(1):38-44.
Validation of serine-threonine protein phosphatase as the herbicide target site of endothall - (Peer Reviewed Journal)
Bajsa, J.N., Pan, Z., Dayan, F.E., Owens, D.K., Duke, S.O. 2012. Validation of serine-threonine protein phosphatase as the herbicide target site of endothall. Journal of Pesticide Biochemistry and Physiology. 102(2):38-44.
Serine/threonine protein phosphatases: multi-purpose enzymes in control of defense mechanisms - (Peer Reviewed Journal)
Bajsa, J.N., Pan, Z., Duke, S.O. 2011. Serine/threonine protein phosphatases: multi-purpose enzymes in control of defense mechanisms. Plant Signaling and Behavior. 6(12):1921-1925.
Serine/threonine protein phosphatases: multi-purpose enzymes in control of defense mechanisms - (Peer Reviewed Journal)
Bajsa, J.N., Pan, Z., Duke, S.O. 2011. Serine/threonine protein phosphatases: multi-purpose enzymes in control of defense mechanisms. Plant Signaling and Behavior. 6(12):1921-1925.
Transcriptional responses to cantharidin a protein phosphatase inhibitor in Arabidopsis thaliana reveal the involvement of multiple signal transduction pathways - (Peer Reviewed Journal)
Bajsa, J.N., Pan, Z., Duke, S.O. 2011. Transcriptional responses to cantharidin a protein phosphatase inhibitor in Arabidopsis thaliana reveal the involvement of multiple signal transduction pathways. Physiologia Plantarum. 143:188-205.
The antiplasmodial activity of norcantharidin analogs - (Peer Reviewed Journal)
Bajsa, J.N., Mccluskey, A., Gordon, C.P., Stewart, S.G., Hill, T.A., Sahu, R., Duke, S.O., Tekwani, B.L. 2010. The antiplasmodial activity of norcantharidin analogs. Bioorganic and Medicinal Chemistry Letters. 20(22):6688-6695.
The Case Against (-)-Catechin Involvement in Allelopathy in Centaurea stoebe (spotted knapweed) - (Peer Reviewed Journal)
Duke, S.O., Dayan, F.E., Bajsa, J.N., Meepagala, K.M., Hufbauer, R.A., Blair, A.C. 2009. The Case Against (-)-Catechin Involvement in Allelopathy in Centaurea stoebe (spotted knapweed). Plant Signaling and Behavior. 4(5):422-424.
Is (-)-Catechin a "Novel Weapon" of Spotted Knapweed (Centaurea stoebe)? - (Peer Reviewed Journal)
Duke, S.O., Blair, A.C., Dayan, F.E., Johnson, R.D., Meepagala, K.M., Cook, D., Bajsa, J.N. 2009. Is (-)-Catechin a "Novel Weapon" of Spotted Knapweed (Centaurea stoebe)? Journal of Chemical Ecology. 35:141-153.
Plasmodium falciparum Serine/Threonine Phosphoprotein Phosphatases (PPP): From Housekeeper to 'Holy Grail' - (Peer Reviewed Journal)
Bajsa, J.N., Duke, S.O., Tekwani, B.L. 2008. Plasmodium falciparum Serine/Threonine Phosphoprotein Phosphatases (PPP): From Housekeeper to 'Holy Grail'. Current Drug Targets. 9:997-1012.
A Survey of Synthetic and Natural Phytotoxic Compounds and Phytoalexins as Potential Antimalarial Compounds - (Peer Reviewed Journal)
Bajsa, J.N., Singh, K., Nanayakkara, D., Duke, S.O., Rimando, A.M., Evidente, A., Tekwani, B.L. 2007. A Survey of Synthetic and Natural Phytotoxic Compounds and Phytoalexins as Potential Antimalarial Compounds. Biological and Pharmaceutical Bulletin. 30(9):1740-1744.