James L Klotz

Research Animal Scientist

• Publications

  • (Clicking on the reprint icon will take you to the publication reprint.)
  • The endocannabinoid system in bovine tissues: characterization of transcript abundance in the growing Holstein steer -(Peer Reviewed Journal)
    Kent-Dennis, C., Klotz, J.L. 2024. The endocannabinoid system in bovine tissues: characterization of transcript abundance in the growing Holstein steer. BMC Veterinary Research. 20. Article 481. https://doi.org/10.1186/s12917-024-04319-x.
    
  • Influence of postruminal casein infusion and exogenous glucagon-like peptide 2 administration on the jejunal mucosal transcriptome in cattle -(Peer Reviewed Journal)
    Trotta, R.J., Swanson, K.C., Klotz, J.L., Harmon, D.L. 2024. Influence of postruminal casein infusion and exogenous glucagon-like peptide 2 administration on the jejunal mucosal transcriptome in cattle. PLOS ONE. 19(8): e0308983. https://doi.org/10.1371/journal.pone.0308983.
    
  • Vasoconstriction induced by ergot alkaloids affects oocyte developmental capacity in pregnant sheep-(Abstract Only)
    
    
  • Ergot alkaloid consumption alters serotonin receptor-induced vasoactivity in ovine umbilical vasculature -(Peer Reviewed Journal)
    Klotz, J.L., Britt, J.L., Greene, M.A., Kent-Dennis, C.E., Duckett, S.K. 2024. Ergot alkaloid consumption alters serotonin receptor-induced vasoactivity in ovine umbilical vasculature. Human and Experimental Toxicology. 43. https://doi.org/10.1177/09603271241269027.
    
  • Impact of endophyte-infected tall fescue seed consumption on endocrine changes associated with intake regulation and post-absorptive metabolism in growing steers -(Peer Reviewed Journal)
    King, M.E., Herzing, H.M., McLoed, K.R., Klotz, J.L., Foote, A.P., Edwards, J.L., Harmon, D.L. 2024. Impact of endophyte-infected tall fescue seed consumption on endocrine changes associated with intake regulation and post-absorptive metabolism in growing steers. Domestic Animal Endocrinology. 89. Article 106873. https://doi.org/10.1016/j.domaniend.2024.106873.
    
  • Serotonin receptor-mediated vasorelaxation occurs primarily through 5-HT4 activation in bovine lateral saphenous vein -(Peer Reviewed Journal)
    Trotta, R.J., Harmon, D.L., Klotz, J.L. 2024. Serotonin receptor-mediated vasorelaxation occurs primarily through 5-HT4 activation in bovine lateral saphenous vein. Physiological Reports. 12: Article e16128. https://doi.org/10.14814/phy2.16128.
    
  • Serotonin stimulates relaxation in ovine saphenous vein precontracted with ergovaline [abstract]-(Abstract Only)
    Klotz, J.L., Duckett, S.K., Checura, C.M. 2024. Serotonin stimulates relaxation in ovine saphenous vein precontracted with ergovaline [abstract]. In: Journal of Animal Science. American Society of Animal Science Annual Meeting, Calgary, Canada, July 21-25, 2024. 102 S3: 282-283.
    
  • Differential gene expression of the endocannabinoid system in bovine tissues -(Abstract Only)
    Kent-Dennis, C., Klotz, J.L. 2024. Differential gene expression of the endocannabinoid system in bovine tissues. Journal of Animal Science. https://doi.org/10.1093/jas/skae234.307.
    
  • 5-HT4 receptor-mediated vasorelaxation occurs through a cyclic mononucleotide-dependent mechanism in the isolated bovine lateral saphenous vein [abstract]-(Abstract Only)
    Trotta, R.J., Harmon, D.L., Klotz, J.L. 2024. 5-HT4 receptor-mediated vasorelaxation occurs through a cyclic mononucleotide-dependent mechanism in the isolated bovine lateral saphenous vein [abstract]. In: Journal of Animal Science. American Society of Animal Science Annual Meeting, Calgary, Canada July 21-25, 2024. 102 S3:268-269.
    
  • The effects of ß-caryophyllene on butyrate utilization and metabolism in Caco 2 cells-(Abstract Only)
    Scroggins, H., Kent-Dennis, C., May, J., Klotz, J.L., Harmon, D.L. 2024. The effects of ß-caryophyllene on butyrate utilization and metabolism in Caco 2 cells. In: Journal of Animal Science. American Society of Animal Science Southern Section Meeting, January 27-30, 2024, Louisville, Kentucky. p. 265-266.
    
  • Changes in satellite cell number in maternal and fetal muscle with 5-hydroxy tryptophan supplementation during late gestation [abstract]-(Abstract Only)
    Udoka, A.S., Iheanacho, G., Worley, G., Klotz, J.L., Duckett, S.K. 2024. Changes in satellite cell number in maternal and fetal muscle with 5-hydroxy tryptophan supplementation during late gestation [abstract]. In: Journal of Animal Science. American Society of Animal Science Annual Meeting, Calgary, Canada July 21-25, 2024. p. 201-202.
    
  • AntagomiR-22-3p injection alters miRNA expression and muscle fiber type of intrauterine growth restricted lambs-(Abstract Only)
    Duckett, S.K., Greene, M.A., Udoka, A.S., Worley, G., Klotz, J.L. 2024. AntagomiR-22-3p injection alters miRNA expression and muscle fiber type of intrauterine growth restricted lambs [abstract]. In: Journal of Animal Science. American Society of Animal Science Annual Meeting, Calgary, Canada, July 21-25, 2024. 102 S3:197-198
    
  • 5-hydroxytryphophan mitigates ergot alkaloid-induced suppression of serotonin and feed intake in cattle -(Peer Reviewed Journal)
    Valente, E.L., Klotz, J.L., Markmann, R.C., Edwards, J.L., Harmon, D.L. 2024. 5-hydroxytryphophan mitigates ergot alkaloid-induced suppression of serotonin and feed intake in cattle. Journal of Animal Science. 102. Article skae083. https://doi.org/10.1093/jas/skae083.
    
  • Levodopa attenuates the feed intake reduction caused by ergot alkaloids in cattle -(Peer Reviewed Journal)
    Valente, E.L., Klotz, J.L., Markmann, R.C., Trotta, R.J., Edwards, J.L., May, J.B., Harmon, D.L. 2024. Levodopa attenuates the feed intake reduction caused by ergot alkaloids in cattle. Journal of Animal Science. 102. Article skae078. https://doi.org/10.1093/jas/skae078.
    
  • Review: Utilizing industrial hemp (Cannabis sativa L.) by-products in livestock rations -(Review Article)
    Altman, A.W., Kent-Dennis, C., Klotz, J.L., McLeod, K.R., Vanzant, E.S., Harmon, D.L. 2023. Review: Utilizing industrial hemp (Cannabis sativa L.) by-products in livestock rations. Animal Feed Science and Technology. 307. Article 115850. https://doi.org/10.1016/j.anifeedsci.2023.115850.
    
  • Use of agomir and antagomir technologies to alter satellite cell proliferation in vitro, mirna expression and muscle fiber hypertrophy in intrauterine growth restricted lambs -(Peer Reviewed Journal)
    Greene, M.A., Worley, G.A., Udoka, A., Powell, R.R., Bruce, T., Klotz, J.L., Bridges, Jr., W.C., Duckett, S.K. 2023. Use of agomir and antagomir technologies to alter satellite cell proliferation in vitro, mirna expression and muscle fiber hypertrophy in intrauterine growth restricted lambs. Frontiers in Molecular Biosciences. 10. Article 1286890. https://doi.org/10.3389/fmolb.2023.1286890.
    
  • Immunomodulation by cannabidiol in bovine primary ruminal epithelial cells-(Peer Reviewed Journal)
    
    
  • Postruminal casein infusion and exogenous glucagon-like peptide 2 administration differentially stimulate pancreatic a-amylase and small intestinal a-glucosidase activity in cattle -(Peer Reviewed Journal)
    Trotta, R.J., Swanson, K.C., Klotz, J.L., Harmon, D.L. 2023. Postruminal casein infusion and exogenous glucagon-like peptide 2 administration differentially stimulate pancreatic a-amylase and small intestinal a-glucosidase activity in cattle. Journal of Nutrition. https://doi.org/10.1016/j.tjnut.2023.08.009.
    
  • Editorial: Natural products in animal feed and production systems -(Review Article)
    Klotz, J.L., MacAdam, J.W., Flythe, M.D. 2023. Editorial: Natural products in animal feed and production systems. Frontiers in Animal Science. 4. Article 1204663. https://doi.org/10.3389/fanim.2023.1204663.
    
  • Impact of ergot alkaloid and steroidal implant on whole-body protein turnover and expression of mTOR pathway proteins in muscle of cattle -(Peer Reviewed Journal)
    Ferguson, T.D., Loos, C.M., Vanzant, E.S., Urschel, K.L., Klotz, J.L., McLeod, K.M. 2023. Impact of ergot alkaloid and steroidal implant on whole-body protein turnover and expression of mTOR pathway proteins in muscle of cattle. Frontiers in Veterinary Science. 10. Article 1104361. https://doi.org/10.3389/fvets.2023.1104361.
    
  • Duration of ergovaline exposure influences serotonin-mediated vasoactivity of bovine mesenteric vasculature -(Peer Reviewed Journal)
    Trotta, R.J., Harmon, D.L., Ji, H., Klotz, J.L. 2023. Duration of ergovaline exposure influences serotonin-mediated vasoactivity of bovine mesenteric vasculature. Journal of Animal Science. 100. https://doi.org/10.1093/jas/skad100.
    
  • Physiological impact of ergot alkaloid consumption in ruminant livestock-(Proceedings)
    
    
  • Effet of quebracho tannin on silage nutritive value, ergovaline concentration, and fermentation parameters of tall fescue with two dry-matter levels -(Peer Reviewed Journal)
    Grote, A.J., Nieman, C.C., Thomas, I.R., Coffey, K.P., Muir, J.P., Klotz, J.L. 2023. Effet of quebracho tannin on silage nutritive value, ergovaline concentration, and fermentation parameters of tall fescue with two dry-matter levels. Agronomy. 13:694. https://doi.org/10.3390/agronomy13030694.
    
  • Influence of intra-abomasal administration of L-DOPA on circulating catecholamines and feed intake in cattle -(Peer Reviewed Journal)
    Valente, E.E., Klotz, J.L., Egert-McLean, A.M., Costa, G.W., May, J.B., Harmon, D.L. 2023. Influence of intra-abomasal administration of L-DOPA on circulating catecholamines and feed intake in cattle. Frontiers in Animal Science. 4. Article 1127575. https://doi.org/10.3389/fanim.2023.1127575.
    
  • Conventional loose mineral with added red clover leaf (Trifolium pratense L.) reverses vasoconstriction associated with tall fescue toxicosis in steers -(Peer Reviewed Journal)
    Davis, B.E., Hamilton, T.A., Johns, J.T., Harmon, D.L., Klotz, J.L., Weinert-Nelson, J.R., Goodman, J.P., May, J., Hi, H., Schrick, F.N., Flythe, M.D. 2022. Conventional loose mineral with added red clover leaf (Trifolium pratense L.) reverses vasoconstriction associated with tall fescue toxicosis in steers. Animal Feed Science and Technology. 115523. https://doi.org/10.1016/j.anifeedsci.2022.115523.
    
  • Mycotoxin ingestion during late gestation alters placentome structure, cotyledon transcriptome, and fetal development in pregnant sheep -(Peer Reviewed Journal)
    Britt, J.L., Greene, M.A., Klotz, J.L., Justice, S.M., Powell, R.R., Noorai, R.E., Bruce, T.F., Duckett, S.K. 2022. Mycotoxin ingestion during late gestation alters placentome structure, cotyledon transcriptome, and fetal development in pregnant sheep. Human and Experimental Toxicology. 41. https://doi.org/10.1177/09603271221119177.
    
  • Effects of bromocriptine on glucose and insulin dynamics in normal and insulin dysregulated horses -(Peer Reviewed Journal)
    Loos, C.M., Urschel, K.L., Vanzant, E.S., Oberhaus, E.L., Bohannan, A.D., Klotz, J.L., Mcleod, K.M. 2022. Effects of bromocriptine on glucose and insulin dynamics in normal and insulin dysregulated horses. Frontiers in Veterinary Science. 9. Article 889888. https://doi.org/10.3389/fvets.2022.889888.
    
  • Ergot alkaloid consumption alters serotonin receptor-induced vasoactivity in ovine umbilical vasculature-(Abstract Only)
    
    
  • The effect of endophyte-infected tall fescue seed consumption on gut and satiety hormones related to intake in Holstein steers-(Abstract Only)
    
    
  • Global impact of ergot alkaloids -(Review Article)
    Klotz, J.L. 2022. Global impact of ergot alkaloids. Toxins. 14(3). Article 186. https://doi.org/10.3390/toxins14030186.
    
  • Joint International Grassland and International Rangeland Congress Kenya 2021: Grasslands Summary-(Proceedings)
    
    
  • Influence of prolonged serotonin and ergovaline pre-exposure on vasoconstriction ex vivo -(Peer Reviewed Journal)
    Valente, E.E., Harmon, D.L., Klotz, J.L. 2021. Influence of prolonged serotonin and ergovaline pre-exposure on vasoconstriction ex vivo. Toxins. 14(1):9. https://doi.org/10.3390/toxins14010009.
    
  • Effect of biochanin A on the rumen microbial community of Holstein steers consuming a high fiber diet and subjected to a subacute acidosis challenge -(Peer Reviewed Journal)
    Harlow, B.E., Flythe, M.D., Klotz, J.L., Harmon, D.L., Aiken, G.E. 2021. Effect of biochanin A on the rumen microbial community of Holstein steers consuming a high fiber diet and subjected to a subacute acidosis challenge. PLoS ONE. 16(7). Article e0253754. https://doi.org/10.1371/journal.pone.0253754.
    
  • Residual effects of abomasal 5-hydroxytryptophan administration on serotonin metabolism in cattle -(Peer Reviewed Journal)
    Valente, E.E., Demasceno, M.L., Klotz, J.L., Harmon, D.L. 2021. Residual effects of abomasal 5-hydroxytryptophan administration on serotonin metabolism in cattle. Domestic Animal Endocrinology. 76. Article 106627. https://doi.org/10.1016/j.domaniend.2021.106627.
    
  • Effects of tall fescue endophyte type and dopamine receptor D2 genotype on cow-calf performance during late gestation and early lactation -(Peer Reviewed Journal)
    Wilbanks, S.A., Justice, S., West, T., Klotz, J.L., Andrae, J.G., Duckett, S.K. 2021. Effects of tall fescue endophyte type and dopamine receptor D2 genotype on cow-calf performance during late gestation and early lactation. Toxins. 13(3). Article 195. https://doi.org/10.3390/toxins13030195.
    
  • Rumen and serum metabolomes in response to endophyte-infected tall fescue seed and isoflavone supplementation in beef steers -(Peer Reviewed Journal)
    Seay, T.B., Melchior, E.A., Clemmons, B.A., Cordero, J.F., Bates, G.E., Flythe, M.D., Klotz, J.L., Ji, H., Goodman, J.P., McLean, K.J., Myer, P.R. 2020. Rumen and serum metabolomes in response to endophyte-infected tall fescue seed and isoflavone supplementation in beef steers. Toxins. 12(12). Article 744. https://doi.org/10.3390/toxins12120744.
    
  • Ergot alkaloid exposure during gestation: I. Impacts on ewe milk production, lamb birth weight and pre-weaning growth rate -(Peer Reviewed Journal)
    Britt, J.L., Greene, M.A., Wilbanks, S.A., Bertrand, J., Klotz, J.L., Bridges, Jr., W.C., Aiken, G.E., Andrae, J.G., Duckett, S.K. 2020. Ergot alkaloid exposure during gestation: I. Impacts on ewe milk production, lamb birth weight and pre-weaning growth rate. Animals. 10(12). Article 2291. https://doi.org/10.3390/ani10122291.
    
  • Ergot alkaloids reduce circulating serotonin in the bovine -(Peer Reviewed Journal)
    Valente, E.E., Klotz, J.L., Ahn, G., McLeod, K.R., Herzing, H.M., King, M., Harmon, D.L. 2020. Ergot alkaloids reduce circulating serotonin in the bovine. Journal of Animal Science. 98(12):skaa362. https://doi.org/10.1093/jas/skaa362.
    
  • Evaluation of oral citrulline administration as a mitigation strategy for fescue toxicosis in sheep -(Peer Reviewed Journal)
    Greene, M.A., Klotz, J.L., Goodman, J.P., May, J.B., Harlow, B.E., Baldwin, W., Strickland, J.R., Britt, J.L., Schrick, F.N., Duckett, S.K. 2020. Evaluation of oral citrulline administration as a mitigation strategy for fescue toxicosis in sheep. Translational Animal Science. 4(4):txaa197. https://doi.org/10.1093/tas/txaa197.
    
  • Feeding tall fescue seed during mid and late gestation influences subsequent postnatal growth, puberty, and carcass quality of offspring -(Peer Reviewed Journal)
    Greene, M.A., Britt, J.L., Bertrand, J., Klotz, J.L., Bridges, Jr., W.C., Andrae, J.G., Duckett, S.K. 2020. Feeding tall fescue seed during mid and late gestation influences subsequent postnatal growth, puberty, and carcass quality of offspring. Animals. 10(10). Article 1859. https://doi.org/10.3390/ani10101859.
    
  • Pattern of postruminal administration of L-tryptophan affects blood serotonin in cattle -(Peer Reviewed Journal)
    Valente, E.E., Klotz, J.L., Ahn, G., Harmon, D.L. 2021. Pattern of postruminal administration of L-tryptophan affects blood serotonin in cattle. Domestic Animal Endocrinology. 74. Article 106574. https://doi.org/10.1016/j.domaniend.2020.106574.
    
  • 5-Hydroxytryptophan strongly stimulates serotoninsynthesis in Holstein steers -(Peer Reviewed Journal)
    Valente, E.E., Klotz, J.L., Harmon, D.L. 2020. 5-Hydroxytryptophan strongly stimulates serotoninsynthesis in Holstein steers. Domestic Animal Endocrinology. 74. Article 106560. https://doi.org/10.1016/j.domaniend.2020.106560.
    
  • Synthetic alkaloid treatment influences the intestinal epithelium and mesenteric adipose transcriptome in Holstein steers -(Peer Reviewed Journal)
    McLean, K.J., Baldwin, R.L., Li, C., Klotz, J.L., Edwards, J.L., McLeod, K.R. 2020. Synthetic alkaloid treatment influences the intestinal epithelium and mesenteric adipose transcriptome in Holstein steers. Frontiers in Veterinary Science. 7. Article 615. https://doi.org/10.3389/fvets.2020.00615.
    
  • Assessment of the contractility of bovine lateral saphenous and digital veins in response to ergot alkaloids-(Abstract Only)
    
    
  • Grazing toxic endophyte-infected tall fescue does not influence pancreatic or small intestinal digestive enzyme activities in beef steers-(Abstract Only)
    
    
  • Mechanisms of programmed nutrition in finishing cattle-(Abstract Only)
    
    
  • A moderate transition of beef heifers to a 90% concentrate diet as a model for subacute ruminal acidosis induced alterations in feeding behavior, rumen environment, reticulorumen motility, and blood acid-base status -(Peer Reviewed Journal)
    Egert-McLean, A.M., Sama, M.P., Klotz, J.L., McLeod, K.R., Kristensen, N.B., Harmon, D.L. 2020. A moderate transition of beef heifers to a 90% concentrate diet as a model for subacute ruminal acidosis induced alterations in feeding behavior, rumen environment, reticulorumen motility, and blood acid-base status. Canadian Journal of Animal Science. 101(1):85-95. https://doi.org/10.1139/cjas-2019-0218.
    
  • Isoflavone supplementation, via red clover hay, alters the rumen microbial community and promotes weight gain of steers grazing mixed grass pastures -(Peer Reviewed Journal)
    Harlow, B.E., Flythe, M.D., Kagan, I., Goodman, J.P., Klotz, J.L., Aiken, G.E. 2020. Isoflavone supplementation, via red clover hay, alters the rumen microbial community and promotes weight gain of steers grazing mixed grass pastures. PLoS One. 15(3): e0229200. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0229200.
    
  • Ruminal motility, reticulo-ruminal fill and eating patterns in steers exposed to ergovaline -(Peer Reviewed Journal)
    Ahn, G., Riccioni, K., Avila, S., Klotz, J.L., Harmon, D.L. 2019. Ruminal motility, reticulo-ruminal fill and eating patterns in steers exposed to ergovaline. Journal of Animal Science. 98(1):1-11. https://doi.org/10.1093/jas/skz374.
    
  • Automated system for characterizing short-term feeding behavior and real-time forestomach motility in cattle -(Peer Reviewed Journal)
    Egert-Mclean, A.M., Sama, M.P., Klotz, J.L., McLeod, K.R., Kristensen, N.B., Harmon, D.L. 2019. Automated system for characterizing short-term feeding behavior and real-time forestomach motility in cattle. Computers and Electronics in Agriculture. 167:105037. https://doi.org/10.1016/j.compag.2019.105037.
    
  • Effects of oral citrulline:malate administration to ewes fed ergot alkaloids during late gestation on neonatal serum amino acids and growth-(Abstract Only)
    
    
  • Ergocornine -(Review Article)
    Klotz, J.L. 2019. Ergocornine. Review Article. https://doi.org/10.1016/B978-0-12-801238-3.98305-3.
    
  • Determination of serotonergic receptor profiles in equine palmar artery and vein and uterine artery-(Abstract Only)
    
    
  • Ergot alkaloid exposure during gestation alters: III. Fetal growth, muscle fiber development, and miRNA transcriptome -(Peer Reviewed Journal)
    Greene, M.A., Britt, J.L., Powell, R., Feltus, F.A., Bridges, Jr., W.C., Bruce, T., Klotz, J.L., Miller, M.F., Duckett, S.K. 2019. Ergot alkaloid exposure during gestation alters: III. Fetal growth, muscle fiber development, and miRNA transcriptome. Journal of Animal Science. https://doi.org/10.1093/jas/skz153.
    
  • Determination of serotonergic receptor profiles in equine palmar artery and vein and uterine artery-(Abstract Only)
    
    
  • Ergot alkaloid exposure during gestation alters: II. Uterine and umbilical artery vasoactivity -(Peer Reviewed Journal)
    Klotz, J.L., Britt, J.L., Miller, M.F., Snider, M.A., Aiken, G.E., Long, N.M., Pratt, S.L., Andrae, J.G., Duckett, S.K. 2019. Ergot alkaloid exposure during gestation alters: II. Uterine and umbilical artery vasoactivity. Journal of Animal Science. 97(4):1891-1902.
    
  • Ergot alkaloid exposure during gestation alters: I. Maternal characteristics and placental development -(Peer Reviewed Journal)
    Britt, J.L., Greene, M.A., Bridges, Jr., W.C., Klotz, J.L., Aiken, G.E., Andrae, J.G., Pratt, S.L., Long, N.M., Schrick, F., Strickland, J.R., Wilbanks, S.A., Miller, Jr., M.F., Koch, B.M., Duckett, S.K. 2019. Ergot alkaloid exposure during gestation alters: I. Maternal characteristics and placental development. Journal of Animal Science. 97(4):1874-1890. https://doi.org/10.1093/jas/skz068.
    
  • Effects of endophyte-infected tall fescue seed and red clover isoflavones on rumen microbial populations and physiological parameters of beef cattle -(Peer Reviewed Journal)
    Melchior, E.A., Smith, J.K., Schneider, L.G., Mulliniks, J.T., Bates, G.E., Flythe, M.D., Klotz, J.L., Ji, H., Goodman, J.P., Lee, A.R., Caldwell, J.M., Myer, P.R. 2018. Effects of endophyte-infected tall fescue seed and red clover isoflavones on rumen microbial populations and physiological parameters of beef cattle. Translational Animal Science. 3:316-328. https://doi.org/10.1093/tas/txy147.
    
  • Effects of red clover isoflavones on tall fescue seed fermentation and microbial populations in vitro -(Peer Reviewed Journal)
    Melchior, E.A., Smith, J.K., Schneider, L.G., Mulliniks, J.T., Bates, G.E., McFarlane, Z.D., Flythe, M.D., Klotz, J.L., Goodman, J.P., Ji, H., Meyer, P.R. 2018. Effects of red clover isoflavones on tall fescue seed fermentation and microbial populations in vitro. Animal Feed Science And Technology. 13(10): e0201866. https://doi.org/10.1371/journal.pone.0201866.
    
  • Interaction of ergovaline with serotonin receptor 5-HT2A in bovine ruminal and mesenteric vasculature -(Peer Reviewed Journal)
    Trotta, R.J., Harmon, D.L., Klotz, J.L. 2018. Interaction of ergovaline with serotonin receptor 5-HT2A in bovine ruminal and mesenteric vasculature. Journal of Animal Science. 96:4912-4922. https://doi.org/10.1093/jas/sky346.
    
  • Effects of source and level of dietary energy supplementation on in vitro digestibility and methane production from tall fescue-based diets -(Peer Reviewed Journal)
    Trotta, R.J., Klotz, J.L., Harmon, D.L. 2018. Effects of source and level of dietary energy supplementation on in vitro digestibility and methane production from tall fescue-based diets. Animal Feed Science And Technology. 242:41-47. https://doi.org/10.1016/j.anifeedsci.2018.05.010.
    
  • Effects of grazing different ergovaline concentrations on vasoactivity of bovine lateral saphenous vein -(Peer Reviewed Journal)
    Klotz, J.L., Aiken, G.E., Egert-McLean, A.M., Schrick, F., Chattopadhyay, N., Harmon, D.L. 2018. Effects of grazing different ergovaline concentrations on vasoactivity of bovine lateral saphenous vein. Journal of Animal Science. 6:3022–3030. doi: 10.1093/jas/sky163.
    
  • Pharmacologic assessment of bovine ruminal and mesenteric vascular serotonin receptor populations-(Peer Reviewed Journal)
    Snider, M.A., Harmon, D.L., Matthews, J.C., Klotz, J.L. 2018. Pharmacologic assessment of bovine ruminal and mesenteric vascular serotonin receptor populations. Journal of Animal Science. 96(4):1570-1578.
    
  • Contractile response of bovine lateral saphenous vein to ergotamine tartrate exposed to different concentrations of molecularly imprinted polymers -(Peer Reviewed Journal)
    Kudupoje, M.B., Klotz, J.L., Yiannikouris, A., Dawson, K.A., McLeod, K.R., Vanzant, E.S. 2018. Contractile response of bovine lateral saphenous vein to ergotamine tartrate exposed to different concentrations of molecularly imprinted polymers. Toxins. 10(2):58. https://doi:10.3390/toxins10020058.
    
  • Tall fescue ergot alkaloids are vasoactive in equine vasculature-(Peer Reviewed Journal)
    Klotz, J.L., McDowell, K.J. 2017. Tall fescue ergot alkaloids are vasoactive in equine vasculature. Journal of Animal Science. 95(11):5151-5160.
    
  • Cell biology symposium: Membrane trafficking and signal transduction-(Peer Reviewed Journal)
    Klotz, J.L. 2017. Cell biology symposium: Membrane trafficking and signal transduction. Journal of Animal Science. 95:2183–2184. doi:10.2527/jas2017.1556.
    
  • Why is intake reduced when cattle are fed tall fescue?-(Proceedings)
    
    
  • Vasoactivity and vasoconstriction changes in cattle related to time off toxic endophyte-infected tall fescue-(Peer Reviewed Journal)
    Klotz, J.L., Aiken, G.E., Bussard, J.R., Foote, A.P., Harmon, D.L., Goff, B.M., Schrick, F., Strickland, J.R. 2016. Vasoactivity and vasoconstriction changes in cattle related to time off toxic endophyte-infected tall fescue. Toxins. 8:271. doi:10.3390/toxins8100271.
    
  • Ergovaline, an endophytic alkaloid. 1. Animal physiology and metabolism -(Review Article)
    Klotz, J.L., Nicol, A.M. 2016. Ergovaline, an endophytic alkaloid. 1. Animal physiology and metabolism. Animal Production Science. 56:1761-1774. http://dx.doi.org/10.1071/AN14962.
    
  • Ergovaline, an endophytic alkaloid. 2. Intake and impact on animal production, with reference to New Zealand -(Review Article)
    Nicol, A.M., Klotz, J.L. 2016. Ergovaline, an endophytic alkaloid. 2. Intake and impact on animal production, with reference to New Zealand. Animal Production Science. 56:1775-1786. http://dx.doi.org/10.1071/AN14963.
    
  • Interaction between a tannin-containing legume and endophyte-infected tall fescue seed on lambs’ feeding behavior and physiology-(Peer Reviewed Journal)
    Villalba, J.J., Spackman, C., Goff, B.M., Klotz, J.L., Griggs, T., MacAdam, J.W. 2015. Interaction between a tannin-containing legume and endophyte-infected tall fescue seed on lambs’ feeding behavior and physiology. Journal of Animal Science. 94:845-857. doi: 10.2527/jas.2015-9790.
    
  • Interaction of isoflavones and endophyte-infected tall fescue seed extract on vasoactivity of bovine mesenteric vasculature-(Peer Reviewed Journal)
    Jia, Y., Harmon, D.L., Flythe, M.D., Klotz, J.L. 2015. Interaction of isoflavones and endophyte-infected tall fescue seed extract on vasoactivity of bovine mesenteric vasculature. Frontiers in Nutrition: Animal Nutrition and Metabolism. doi: 10.3389/fnut.2015.00032.
    
  • Physiologic effects of ergot alkaloids: What happens when excretion does not equal consumption?-(Review Article)
    Klotz, J.L. 2015. Physiologic effects of ergot alkaloids: What happens when excretion does not equal consumption? Journal of Animal Science. 93:5512-5521.
    
  • Activities and effects of ergot alkaloids on livestock physiology and production-(Review Article)
    Klotz, J.L. 2015. Activities and effects of ergot alkaloids on livestock physiology and production. Toxins. 7:2801-2821. doi:10.3390/toxins7082801.
    
  • The difficulties in reviewing ergovaline-(Proceedings)
    Nicol, A.M., Klotz, J.L. 2018. The difficulties in reviewing ergovaline. Proceedings New Zealand Society of Animal Production. pp. 18.
    
  • The difficulties in reviewing ergovaline-(Abstract Only)
    Nicol, A.M., Klotz, J.L. 2015. The difficulties in reviewing ergovaline. Proceedings New Zealand Society of Animal Production. pp. 35-36.
    
  • Effect of grazing seedhead-suppressed tall fescue pasture on the vasoactivity of serotonin receptors-(Abstract Only)
    
    
  • Interaction between a tannin-containing legume and endophyte-infected tall fescue seed on lambs’ feeding behavior and physiology-(Abstract Only)
    
    
  • Recent investigations of ergot alkaloids incorporated into plant and/or animal systems-(Review Article)
    Klotz, J.L., Smith, D.L. 2015. Recent investigations of ergot alkaloids incorporated into plant and/or animal systems. Frontiers in Chemistry: Chemical Biology. 3:23. doi:10.3389/fchem.2015.00023.
    
  • Hops (Humulus lupulus) ß-acid as an inhibitor of caprine rumen hyper-ammonia-producing bacteria in vitro-(Peer Reviewed Journal)
    Flythe, M.D., Aiken, G.E., Gellin, G.L., Klotz, J.L., Goff, B.M., Andries, K. 2015. Hops (Humulus lupulus) ß-acid as an inhibitor of caprine rumen hyper-ammonia-producing bacteria in vitro. Agriculture, Food and Analytical Bacteriology. 5:29-36.
    
  • Cases of ergotism in livestock and associated ergot alkaloid concentrations in feed-(Peer Reviewed Journal)
    Craig, A., Klotz, J.L., Duringer, J.M. 2015. Cases of ergotism in livestock and associated ergot alkaloid concentrations in feed. Frontiers in Chemistry: Chemical Biology. 3:8. doi:10.3389/fchem.2015.00008.
    
  • Tall fescue seed extraction and partial purification of ergot alkaloids-(Peer Reviewed Journal)
    Huihua, J., Fannin, N., Klotz, J.L., Bush, L.P. 2014. Tall fescue seed extraction and partial purification of ergot alkaloids. Frontiers in Chemistry: Chemical Biology. 2:110.
    
  • Physiologic effects of ergot alkaloids: What happens when excretion does not equal absorption?-(Abstract Only)
    Klotz, J.L. 2015. Physiologic effects of ergot alkaloids: What happens when excretion does not equal absorption?. American Society of Animal Science Southern Section Meeting. Pg. 92.
    
  • Development of a methodology to measure the effect of ergot alkaloids on forestomach motility using real-time wireless telemetry-(Peer Reviewed Journal)
    Egert, A.M., Klotz, J.L., McLeod, K.R., Harmon, D.L. 2014. Development of a methodology to measure the effect of ergot alkaloids on forestomach motility using real-time wireless telemetry. Frontiers in Chemistry: Chemical Biology. 2:90.
    
  • Effect of intake on fasting heat production, respiratory quotient and plasma metabolites measured using the washed rumen technique-(Peer Reviewed Journal)
    Kim, D., McLeod, K.R., Koontz, A.F., Foote, A.P., Klotz, J.L., Harmon, D.L. 2015. Effect of intake on fasting heat production, respiratory quotient and plasma metabolites measured using the washed rumen technique. Animal. 9:58-66.
    
  • Effect of fescue toxicosis on whole body energy and nitrogen balance, in situ degradation and ruminal passage rates in Holstein steers-(Peer Reviewed Journal)
    Koontz, A.F., Kim, D., Mc Leod, K.R., Klotz, J.L., Harmon, D.L. 2014. Effect of fescue toxicosis on whole body energy and nitrogen balance, in situ degradation and ruminal passage rates in Holstein steers. Animal Production Science. 55:988-998. doi.org/10.1071/AN14037.
    
  • Isolating and using sections of bovine mesenteric artery and vein as a bioassay to test for vasoactivity in the small intestine-(Peer Reviewed Journal)
    Klotz, J.L., Barnes, A.J. 2014. Isolating and using sections of bovine mesenteric artery and vein as a bioassay to test for vasoactivity in the small intestine. Journal of Visualized Experiments. 92:e52020.
    
  • Effects of ergot alkaloid exposure on serotonin receptor mRNA in the smooth muscle of the bovine gastrointestinal tract-(Abstract Only)
    Klotz, J.L., Kim, D., Foote, A.P., Harmon, D.L. 2014. Effects of ergot alkaloid exposure on serotonin receptor mRNA in the smooth muscle of the bovine gastrointestinal tract. Joint Meeting of the ADSA, AMSA, ASAS and PSA. 92(E.Suppl.2):890.
    
  • Analysis of rumen motility patterns using a wireless telemetry system to characterize bovine reticuloruminal contractions-(Abstract Only)
    Egert, A.M., Mcleod, K.R., Klotz, J.L., Harmon, D.L. 2014. Analysis of rumen motility patterns using a wireless telemetry system to characterize bovine reticuloruminal contractions. Joint Meeting of the ADSA, AMSA, ASAS and PSA. 92(E.Suppl.2):804.
    
  • Effects of fescue toxicosis induced by endophyte-infected tall fescue seed on forestomach epithelial gene expression in Angus steers-(Abstract Only)
    Kim, D., Klotz, J.L., Harmon, D.L. 2014. Effects of fescue toxicosis induced by endophyte-infected tall fescue seed on forestomach epithelial gene expression in Angus steers. Joint Meeting of the ADSA, AMSA, ASAS and PSA. 92(E.Suppl.2):898.
    
  • Effect of acute exposure to ergot alkaloids on short-chain fatty acid absorption and barrier function of isolated bovine ruminal epithelium-(Abstract Only)
    Foote, A.P., Penner, G.P., Walpole, M.E., Klotz, J.L., Bush, L.P., Harmon, D.L. 2014. Effect of acute exposure to ergot alkaloids on short-chain fatty acid absorption and barrier function of isolated bovine ruminal epithelium. Joint Meeting of the ADSA, AMSA, ASAS and PSA. 92(E.Suppl.2):874.
    
  • Acute exposure to ergot alkaloids from endophyte-infected tall fescue does not alter absorptive or barrier function of the isolated ruminal epithelium-(Peer Reviewed Journal)
    Foote, A.P., Penner, G.P., Walpole, M.E., Klotz, J.L., Brown, K.R., Bush, L.P., Harmon, D.L. 2014. Acute exposure to ergot alkaloids from endophyte-infected tall fescue does not alter absorptive or barrier function of the isolated ruminal epithelium. Animal. 8(7):1106-1112.
    
  • Bovine lateral saphenous veins exposed to ergopeptine alkaloids do not relax-(Peer Reviewed Journal)
    Pesqueira, A., Harmon, D.L., Branco, A.F., Klotz, J.L. 2014. Bovine lateral saphenous veins exposed to ergopeptine alkaloids do not relax. Journal of Animal Science. 92:1213-1218.
    
  • Dietary exposure to ergot alkaloids decreases contractility of bovine mesenteric vasculature-(Peer Reviewed Journal)
    Egert, A.M., Kim, D., Schrick, F., Harmon, D.L., Klotz, J.L. 2014. Dietary exposure to ergot alkaloids decreases contractility of bovine mesenteric vasculature. Journal of Animal Science. 92:1768-1779.
    
  • Postgraze assessment of toxicosis symptoms for steers grazed on toxic and novel endophyte-infected tall fescue pasture-(Peer Reviewed Journal)
    Aiken, G.E., Klotz, J.L., Johnson, J.M., Strickland, J.R., Schrick, F.N. 2013. Postgraze assessment of toxicosis symptoms for steers grazed on toxic and novel endophyte-infected tall fescue pasture. Journal of Animal Science. 91:5878-5884.
    
  • Ergot alkaloids from endophyte-infected tall fescue decrease reticulo-ruminal epithelial blood flow and volatile fatty acid absorption from a washed reticulorumen-(Peer Reviewed Journal)
    Foote, A.P., Kristensen, N.B., Klotz, J.L., Kim, D., Koontz, A.F., Mcleod, K.R., Bush, L.P., Schrick, F.N., Harmon, D.L. 2013. Ergot alkaloids from endophyte-infected tall fescue decrease reticulo-ruminal epithelial blood flow and volatile fatty acid absorption from a washed reticulorumen. Journal of Animal Science. 91:5366-5378.
    
  • Antimicrobial activity of red clover (Trifolium pratense L.) extract on caprine hyper ammonia-producing bacteria-(Peer Reviewed Journal)
    Flythe, M.D., Harrison, B., Kagan, I., Klotz, J.L., Gellin, G.L., Goff, B.M., Aiken, G.E. 2013. Antimicrobial activity of red clover (Trifolium pratense L.) extract on caprine hyper ammonia-producing bacteria. Agriculture, Food and Analytical Bacteriology. 3:176-185.
    
  • Evaluation of a rapid determination of heat production and respiratory quotient in holstein steers using the washed rumen technique-(Peer Reviewed Journal)
    Kim, D., Mcleod, K.R., Klotz, J.L., Koontz, A.F., Foote, A.P., Harmon, D.L. 2013. Evaluation of a rapid determination of heat production and respiratory quotient in holstein steers using the washed rumen technique. Journal of Animal Science. 91:4267-4276.
    
  • Antagonism of lateral saphenous vein serotonin receptors from steers grazing endophyte-free, wild-type, or novel endophyte-infected tall fescue-(Peer Reviewed Journal)
    Klotz, J.L., Aiken, G.E., Johnson, J.M., Brown, K.R., Bush, L.P., Strickland, J.R. 2013. Antagonism of lateral saphenous vein serotonin receptors from steers grazing endophyte-free, wild-type, or novel endophyte-infected tall fescue. Journal of Animal Science. 91:4492-4500.
    
  • Alteration of fasting heat production during fescue toxicosis in Holstein steers-(Peer Reviewed Journal)
    Koontz, A.F., Kim, D., Foote, A.P., Bush, L.P., Klotz, J.L., Mcleod, K.R., Harmon, D.L. 2013. Alteration of fasting heat production during fescue toxicosis in Holstein steers. Journal of Animal Science. 91:3881-3888.
    
  • Antimicrobial effects of hops (Humulus lupulus) beta-acid on the growth and ammonia production of caprine ruminal hyper-ammonia-producing bacteria-(Abstract Only)
    Flythe, M.D., Klotz, J.L., Gellin, G.L., Aiken, G.E. 2013. Antimicrobial effects of hops (Humulus lupulus) beta-acid on the growth and ammonia production of caprine ruminal hyper-ammonia-producing bacteria. American Society for Microbiology General Meeting. Pg. 22.
    
  • Bovine lateral saphenous veins exposed to ergopeptine alkaloids do not relax-(Abstract Only)
    Klotz, J.L., Pesqueira, A., Branco, A.F., Harmon, D.L. 2013. Bovine lateral saphenous veins exposed to ergopeptine alkaloids do not relax. J. Anim. Sci. Vol. 91, E-Suppl. 2:92.
    
  • Effect of endophyte-infected tall fescue seed on ruminal metabolism and physiology in Angus steers-(Abstract Only)
    Kim, D.H., Klotz, J.L., Harmon, D.L. 2013. Effect of endophyte-infected tall fescue seed on ruminal metabolism and physiology in Angus steers. J. Anim. Sci. Vo. 91, E-Suppl. 2:522-523.
    
  • Equine palmar artery, palmar vein and uterine artery express different populations of vasoactive biogenic amine receptors-(Abstract Only)
    Hestad, D.A., Mcdowell, K.J., Klotz, J.L. 2013. Equine palmar artery, palmar vein and uterine artery express different populations of vasoactive biogenic amine receptors. J. Anim. Sci. Vol. 91, E-Suppl. 2:566.
    
  • Dietary exposure to ergot alkaloids decreases contractility of bovine mesenteric vasculature-(Abstract Only)
    Egert, A.M., Kim, D., Harmon, D.L., Klotz, J.L. 2013. Dietary exposure to ergot alkaloids decreases contractility of bovine mesenteric vasculature. J. Anim. Sci. Vol. 91, E-Suppl. 2:214.
    
  • Effect of fescue toxicosis on ruminal kinetics, nitrogen and energy balance in Holstein steers-(Abstract Only)
    Koontz, A.F., Foote, A.P., Kim, D.H., Klotz, J.L., Mcleod, K.R., Harmon, D.L. 2013. Effect of fescue toxicosis on ruminal kinetics, nitrogen and energy balance in Holstein steers. J. Anim. Sci. Vol. 91, E-Suppl. 2:92.
    
  • Effect of fescue toxicosis on nitrogen and energy balance in Holstein steers-(Abstract Only)
    Koontz, A.F., Kim, D.H., Foote, A.P., Bush, L.P., Klotz, J.L., Mcleod, K.R., Harmon, D.L. 2013. Effect of fescue toxicosis on nitrogen and energy balance in Holstein steers. In: Energy and Protein Metabolism and Nutrition in Sustainable Animal Production. 134:67-68.
    
  • Application of washed rumen technique for rapid determination of fasting heat production in steers-(Abstract Only)
    Kim, D.H., Mcleod, K.R., Klotz, J.L., Koontz, A.F., Foote, A.P., Harmon, D.L. 2013. Application of washed rumen technique for rapid determination of fasting heat production in steers. In: Energy and Protein Metabolism and Nutrition in Sustainable Animal Production. 134:235-236.
    
  • Ergot alkaloids produced by endophyte-infected tall fescue decrease rumen epithelial blood flow of cattle-(Proceedings)
    Foote, A.P., Kristensen, N.B., Klotz, J.L., Mcleod, K.R., Bush, L.P., Harmon, D.L. 2013. Ergot alkaloids produced by endophyte-infected tall fescue decrease rumen epithelial blood flow of cattle. American Forage and Grassland Council Conference Proceedings. Pg. 8.
    
  • Evaluation of a rapid determination of heat production and respiratory quotient in Holstein steers using the washing rumen technique-(Experiment Station)
    Kim, D., Mcleod, K.R., Klotz, J.L., Koontz, A.F., Foote, A.P., Harmon, D.L. 2014. Evaluation of a rapid determination of heat production and respiratory quotient in Holstein steers using the washing rumen technique. Kentucky Beef Report. pgs. 26-28.
    
  • Alteration of basal metabolic rate in Holstein steers during fescue toxicosis-(Experiment Station)
    Koontz, A.F., Foote, A.P., Kim, D., Bush, L.P., Klotz, J.L., Mcleod, K.R., Harmon, D.L. 2014. Alteration of basal metabolic rate in Holstein steers during fescue toxicosis. Kentucky Beef Report. pgs. 7-9.
    
  • Vascular activity increases with time off of tall fescue-(Experiment Station)
    Klotz, J.L., Aiken, G.E., Foote, A.P., Bussard, J.R., Brown, K.R., Goff, B.M., Harmon, D.L., Strickland, J.R. 2014. Vascular activity increases with time off of tall fescue. Kentucky Beef Report. pgs. 19-22.
    
  • Constriction of bovine vasculature caused by endophyte-infected tall fescue seed extract is similar to pure ergovaline-(Experiment Station)
    Foote, A.P., Harmon, D.L., Brown, K.R., Strickland, J.R., Mcleod, K.R., Bush, L.P., Klotz, J.L. 2014. Constriction of bovine vasculature caused by endophyte-infected tall fescue seed extract is similar to pure ergovaline. Kentucky Beef Report. pgs. 13-15.
    
  • Ergot alkaloids reduce rumen epithelial blood flow and volatile fatty acid absorption-(Experiment Station)
    Foote, A.P., Kristensen, N.B., Klotz, J.L., Kim, D., Koontz, A.F., Mcleod, K.R., Bush, L.P., Harmon, D.L. 2014. Ergot alkaloids reduce rumen epithelial blood flow and volatile fatty acid absorption. Kentucky Beef Report. pgs. 16-19.
    
  • Validation of a housekeeping gene for use in bovine vascular gene expression studies-(Abstract Only)
    Klotz, J.L., Brown, K.R., Matthews, J.C., Boling, J.A., Strickland, J.R. 2012. Validation of a housekeeping gene for use in bovine vascular gene expression studies. J. Anim. Sci. Vol 90, Suppl 3:pg 35.
    
  • Ergovaline disappearance from a ruminally incubated buffer-(Abstract Only)
    Foote, A.P., Kristensen, N.B., Klotz, J.L., Brown, K.R., Strickland, J.R., Kim, D.H., Koontz, A.E., Mcleod, K.R., Bush, L.P., Harmon, D.L. 2012. Ergovaline disappearance from a ruminally incubated buffer. J. Anim. Sci. Vol. 90, Suppl. 3:94.
    
  • Alteration of fasting heat production during fescue toxicosis in Holstein steers-(Abstract Only)
    Koontz, A.F., Foote, A.P., Kim, D.H., Bush, L.P., Klotz, J.L., Mcleod, K.R., Harmon, D.L. 2012. Alteration of fasting heat production during fescue toxicosis in Holstein steers. J. Anim. Sci. Vol. 90, Suppl. 3:622-623.
    
  • Ergot alkaloids decrease rumen epithelial blood flow-(Abstract Only)
    Foote, A.P., Kristensen, N.B., Klotz, J.L., Kim, D.H., Koontz, A.F., Mcleod, K.R., Bush, L.P., Harmon, D.L. 2012. Ergot alkaloids decrease rumen epithelial blood flow. J. Anim. Sci. Vol. 90, Suppl. 3:431-432.
    
  • Evaluation of a rapid determination of heat production and respiratory quotient in Holstein steers using the washed rumen technique-(Abstract Only)
    Kim, D.H., Mcleod, K.R., Klotz, J.L., Koontz, A.F., Foote, A.P., Harmon, D.L. 2012. Evaluation of a rapid determination of heat production and respiratory quotient in Holstein steers using the washed rumen technique. J. Anim. Sci. Vol. 90, Suppl. 3:99.
    
  • Lateral saphenous vein responses to serotonergic and a-adrenergic receptor agonists increase with time off endophyte-infected tall fescue-(Abstract Only)
    Klotz, J.L., Bussard, J.R., Aiken, G.E., Foote, A.P., Harmon, D.L., Brown, K.R., Goff, B.M., Strickland, J.R. 2012. Lateral saphenous vein responses to serotonergic and a-adrenergic receptor agonists increase with time off endophyte-infected tall fescue. J. Anim. Sci. Vol. 90, Suppl. 3:34.
    
  • Changes in bovine vascular contraction and constriction relative to time off endophyte-infected tall fescue-(Abstract Only)
    Bussard, J.R., Aiken, G.E., Strickland, J.R., Brown, K.R., Goff, B.M., Foote, A.P., Klotz, J.L. 2012. Changes in bovine vascular contraction and constriction relative to time off endophyte-infected tall fescue. J. Anim. Sci. Vol. 90, Suppl. 3:34.
    
  • Steer and pasture responses for a novel endophyte tall fescue developed for the upper transition zone-(Peer Reviewed Journal)
    Johnson, J.M., Aiken, G.E., Phillips, T.D., Barrett, M., Klotz, J.L., Schrick, F.N. 2012. Steer and pasture responses for a novel endophyte tall fescue developed for the upper transition zone. Journal of Animal Science. 90:2402-2409.
    
  • Constriction of bovine vasculature by endophyte-infected tall fescue seed extract is similar to pure ergovaline-(Peer Reviewed Journal)
    Foote, A.P., Harmon, D.L., Brown, K.R., Strickland, J.R., Mcleod, K.R., Bush, L.P., Klotz, J.L. 2012. Constriction of bovine vasculature by endophyte-infected tall fescue seed extract is similar to pure ergovaline. Journal of Animal Science. 90:1603-1609.
    
  • Evaluation of a ruminally dosed tall fescue seed extract as a model for fescue toxicosis in steers-(Peer Reviewed Journal)
    Koontz, A.F., Bush, L.P., Klotz, J.L., Mcleod, K.R., Schrick, F.N., Harmon, D.L. 2012. Evaluation of a ruminally dosed tall fescue seed extract as a model for fescue toxicosis in steers. Journal of Animal Science. 90:914-921.
    
  • Alterations in serotonin receptor-induced contractility of bovine lateral saphenous vein in cattle grazing endophyte-infected tall fescue-(Peer Reviewed Journal)
    Klotz, J.L., Brown, K.R., Xue, Y., Matthews, J.C., Boling, J.A., Burris, W.R., Bush, L.P., Strickland, J.R. 2012. Alterations in serotonin receptor-induced contractility of bovine lateral saphenous vein in cattle grazing endophyte-infected tall fescue. Journal of Animal Science. 90:682-693.
    
  • Protein degradation of smooth bromegrass switchgrass and big bluestem in grazing cattle-(Peer Reviewed Journal)
    Kirch, B.H., Moser, L.E., Waller, S.S., Klopfenstein, T.J., Klotz, J.L. 2011. Protein degradation of smooth bromegrass switchgrass and big bluestem in grazing cattle. The Professional Animal Scientist. 27:422-427.
    
  • Disrupted hair follicle activity in cattle grazing endophyte-infected tall fescue in the summer insulates core body temperatures-(Peer Reviewed Journal)
    Aiken, G.E., Klotz, J.L., Looper, M.L., Tabler, S.F., Schrick, F.N. 2011. Disrupted hair follicle activity in cattle grazing endophyte-infected tall fescue in the summer insulates core body temperatures. Professional Animal Scientist. 27:336-343.
    
  • Effect of ergot alkaloids on contractility of bovine right ruminal artery and vein-(Peer Reviewed Journal)
    Foote, A.P., Harmon, D.L., Strickland, J.R., Bush, L.P., Klotz, J.L. 2011. Effect of ergot alkaloids on contractility of bovine right ruminal artery and vein. Journal of Animal Science. 89:2944-2949.
    
  • Contractile response of bovine lateral saphenous vein to ergovaline serotonin2A a2A- and a2C-adrenergic receptor agonists relative to time off endophyte-infected tall fescue-(Abstract Only)
    Klotz, J.L., Aiken, G.E., Foote, A.P., Bush, L.P., Brown, K.R., Goff, B.M., Strickland, J.R. 2011. Contractile response of bovine lateral saphenous vein to ergovaline serotonin2A a2A- and a2C-adrenergic receptor agonists relative to time off endophyte-infected tall fescue. Joint Meeting of the ADSA, AMSA, ASAS and PSA. 89(E-Suppl. 1):50.
    
  • Endophyte-infected tall fescue seed extract induces constriction of bovine vasculature-(Abstract Only)
    Foote, A.P., Harmon, D.L., Brown, K.R., Strickland, J.R., Mcleod, K.R., Bush, L.P., Klotz, J.L. 2011. Endophyte-infected tall fescue seed extract induces constriction of bovine vasculature. Joint Meeting of the ADSA, AMSA, ASAS and PSA. 89(E-Suppl. 1):49-50.
    
  • Ergot alkaloids: toxicokinetics and vascular effects-(Book / Chapter)
    Strickland, J.R., Brown, K.R., Aiken, G.E., Klotz, J.L., Flythe, M.D. 2012. Ergot alkaloids: toxicokinetics and vascular effects. International Symposium on Fungal Endophytes of Grasses. pgs 14-19.
    
  • A vascular contractility bioassay using bovine right ruminal artery and vein-(Peer Reviewed Journal)
    Klotz, J.L., Bush, L.P., Strickland, J.R. 2011. A vascular contractility bioassay using bovine right ruminal artery and vein. Journal of Animal Science. 89:1944-1951.
    
  • Effect of Ergot Alkaloids on Bovine Foregut Vasculature-(Experiment Station)
    Foote, A.P., Klotz, J.L., Harmon, D.L., Bush, L.P., Strickland, J.R. 2010. Effect of Ergot Alkaloids on Bovine Foregut Vasculature. Kentucky Beef Report. pgs 33-36.
    
  • Tall Fescue Alkaloids Bind Serotonin Receptors in Cattle-(Experiment Station)
    Klotz, J.L., Strickland, J.R., Bush, L.P., Brown, K.R., Aiken, G.E. 2010. Tall Fescue Alkaloids Bind Serotonin Receptors in Cattle. Kentucky Beef Report. pgs 37-43.
    
  • Ergot Alkaloids: Toxicokinetics and Vascular Effects in Grazing Animals-(Abstract Only)
    Strickland, J.R., Aiken, G.E., Klotz, J.L., Flythe, M.D., Brown, K.R. 2010. Ergot Alkaloids: Toxicokinetics and Vascular Effects in Grazing Animals. International Symposium on Fungal Endophytes of Grasses. pp 103-104.
    
  • An Extract of Endophyte Infected Tall Fescue Seed Induces Vasoconstriction of Bovine Foregut Vasculature-(Abstract Only)
    Foote, A.P., Klotz, J.L., Bush, L.P., Strickland, J.R., Harmon, D.L. 2010. An Extract of Endophyte Infected Tall Fescue Seed Induces Vasoconstriction of Bovine Foregut Vasculature. International Symposium on Fungal Endophytes of Grasses. pp 33-34.
    
  • Efficacy of a Fescue Seed Extract in Inducing Toxicosis in Cattle-(Abstract Only)
    Koontz, A.F., Bush, L.P., Klotz, J.L., Mcleod, K.R., Harmon, D.L. 2010. Efficacy of a Fescue Seed Extract in Inducing Toxicosis in Cattle. International Symposium on Fungal Endophytes of Grasses. p 58.
    
  • A Simple Tall Fescue Seed Extraction and Partial Purification of Ergovaline-(Abstract Only)
    Fannin, F., Ji, H., Klotz, J.L., Bush, L.P. 2010. A Simple Tall Fescue Seed Extraction and Partial Purification of Ergovaline. International Symposium on Fungal Endophytes of Grasses. p 31.
    
  • Development of a fescue toxicosis model using a fescue seed extract-(Abstract Only)
    Koontz, A.F., Bush, L.P., Klotz, J.L., Mcleod, K.R., Schrick, F.N., Harmon, D.L. 2010. Development of a fescue toxicosis model using a fescue seed extract. J. Anim. Sci. 88:(2/J). Dairy Sci. 93( 1)/Poult. Sci. 89(1):704.
    
  • Ergot alkaloids induce vasoconstriction of bovine foregut vasculature-(Abstract Only)
    Foote, A.P., Klotz, J.L., Harmon, D.L., Bush, L.P., Strickland, J.R. 2010. Ergot alkaloids induce vasoconstriction of bovine foregut vasculature. J. Anim. Sci. 88( 2/J). Dairy Sci. Vol. 93(1)/Poult. Sci. 89(1):701.
    
  • Antagonism of 5-hydroxytryptamine2A Receptor Results in Decreased Contractile Response of Bovine Lateral Saphenous Vein to Tall Fescue Alkaloids-(Abstract Only)
    Klotz, J.L., Strickland, J.R., Bush, L.P., Kirch, B.H., Brown, K.R. 2010. Antagonism of 5-hydroxytryptamine2A Receptor Results in Decreased Contractile Response of Bovine Lateral Saphenous Vein to Tall Fescue Alkaloids. J. Anim. Sci. Vol. 88, E-Suppl. 2/J. Dairy Sci. Vol. 93, E-Suppl. 1/Poult. Sci. Vol. 89, E-Suppl. 1. pg 55.
    
  • Tall fescue alkaloids cause vasoconstriction in equine medial palmar artery and vein-(Abstract Only)
    Klotz, J.L., Mcdowell, K.J. 2010. Tall fescue alkaloids cause vasoconstriction in equine medial palmar artery and vein. J. Anim. Sci. 88(2/J). Dairy Sci. 93(1)/Poult. Sci. 89(1):55.
    
  • Contractile response of fescue-naïve bovine lateral saphenous veins to increasing concentrations of tall fescue alkaloids-(Peer Reviewed Journal)
    Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Strickland, J.R. 2009. Contractile Response of Fescue-Naïve Bovine Lateral Saphenous Veins to Increasing Concentrations of Tall Fescue Alkaloids. J Anim Sci. 88:408-415.
    
  • USDA - Kentucky Report (Annual Report to SERA-IEG 8, Tall Fescue Toxicosis/Endophyte Workshop)-(Other)
    Klotz, J.L., Bush, L.P., Strickland, J.R., West, C.P., Dinkins, R.D. 2009. USDA - Kentucky Report (Annual Report to SERA-IEG 8, Tall Fescue Toxicosis/Endophyte Workshop). SERA-IEG 8. p 62-66.
    
  • Development and validation of a LC-MS method for quantitation of ergot alkaloids in lateral saphenous vein tissue-(Peer Reviewed Journal)
    Smith, D.L., Smith, L.L., Shafer, W.D., Klotz, J.L., Strickland, J.R. 2009. Development and validation of a LC-MS method for quantitation of ergot alkaloids in lateral saphenous vein tissue. Journal of Agricultural and Food Chemistry. 57:7213-7220.
    
  • Ergot Alkaloid-Induced Blood Vessel Dysfunction Contributes to Fescue Toxicosis-(Peer Reviewed Journal)
    Strickland, J.R., Aiken, G.E., Klotz, J.L. 2009. Ergot Alkaloid-Induced Blood Vessel Dysfunction Contributes to Fescue Toxicosis. Forage and Grazinglands. 4Nov09.
    
  • Validation of Right Ruminal Vein and Artery as Models of Bovine Foregut Vasculature-(Abstract Only)
    Klotz, J.L., Bush, L.P., Strickland, J.R. 2009. Validation of Right Ruminal Vein and Artery as Models of Bovine Foregut Vasculature. Joint Abstracts of the American Dairy Science and Society of Animal Science. 87,E-Supp 2. p.83(M257).
    
  • Bioaccumulation of Ergovaline in Bovine Lateral Saphenous Veins in Vitro-(Peer Reviewed Journal)
    Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Strickland, J.R. 2009. Bioaccumulation of Ergovaline in Bovine Lateral Saphenous Veins in Vitro. J Anim Sci. 2009. 87:2437-2447.
    
  • USDA - Kentucky Report (Annual Report to SERA-IEG 8, Tall Fescue Toxicosis/Endophyte Workshop)-(Other)
    Klotz, J.L., Smith, L.L., Bush, L.P., Strickland, J.R. 2008. USDA - Kentucky Report (Annual Report to SERA-IEG 8, Tall Fescue Toxicosis/Endophyte Workshop). SERA-IEG 8. pgs 54-58.
    
  • Tennessee Report (Annual Report to SERA-IEG8 Tall Fescue Toxicosis/Endophyte Workshop)-(Other)
    Norman, R., Lane, C.D., Fisher, A.E., Campbell, B.T., Schrick, F.N., Waller, J.C., Block, S.S., Kojima, C.J., Spiers, D.E., Klotz, J.L., Strickland, J.R., Bates, G.E., Riggins, J.C., Hopkins, F.M., Edwards, J.L., Prado, T. 2008. Tennessee Report (Annual Report to SERA-IEG8 Tall Fescue Toxicosis/Endophyte Workshop). SERA-IEG 8. Meeting Report pgs 110-121.
    
  • Growing steers grazing high versus low endophyte (Neotyphodium coenophialum)-infected tall fescue have reduced serum enzymes increased hepatic glucogenic enzymes and reduced liver and carcass mass-(Peer Reviewed Journal)
    Brown, K.R., Anderson, G.A., Son, K., Rentfrow, G., Bush, L.P., Klotz, J.L., Strickland, J.R., Boling, J.A., Matthews, J.C. 2009. Growing steers grazing high versus low endophyte (Neotyphodium coenophialum)-infected tall fescue have reduced serum enzymes, increasedhepatic glucogenic enzymes, and reduced liver and carcass tissue mass. J. Anim. Sci. 87:748-760.
    
  • Technical note: comparison between two tracing methods with ultrasonography to determine lumen area of the caudal artery in beef cattle-(Peer Reviewed Journal)
    Aiken, G.E., Klotz, J.L., Kirch, B.H., Strickland, J.R., Boykin, D.L. 2008. Technical note: Comparison between two tracing methods with ultrasonography to determine lumen area of the caudal artery in beef cattle. Journal of Animal Science. 87:371-374.
    
  • Steers Grazing Toxic Neotyphodium Coenophialum-Infected Forages Have Increased Hepatic Gluconeogenic Capacity-(Abstract Only)
    Brown, K.R., Klotz, J.L., Strickland, J.R., Bush, L.P., Boling, J.A., Matthews, J.C. 2008. Steers Grazing Toxic Neotyphodium Coenophialum-Infected Forages Have Increased Hepatic Gluconeogenic Capacity. J. .Anim. Sci. Vol. 86, E-Suppl. 2. p 101.
    
  • Grazing Endophyte-Infected Tall Fescue Alters Serotonin Receptor-Induced Contractility of Bovine Lateral Saphenous Veins-(Abstract Only)
    Klotz, J.L., Brown, K.R., Xue, Y., Matthews, J.C., Boling, J.A., Bush, L.P., Strickland, J.R. 2008. Grazing Endophyte-Infected Tall Fescue Alters Serotonin Receptor-Induced Contractility of Bovine Lateral Saphenous Veins. J. Anim. Sci. Vol. 86. p 102.
    
  • The Effect of Toxic Tall Fescue on Cellobiose-Utilizing Populations in the Bovine Rumen-(Abstract Only)
    Flythe, M.D., Gellin, G.L., Klotz, J.L., Strickland, J.R., Brown, K.R., Matthews, J.C., Boling, J.A. 2008. The Effect of Toxic Tall Fescue on Cellobiose-Utilizing Populations in the Bovine Rumen. American Society for Microbiology Annual Meeting. ISBN 978-1555814939. Z-040 (Abstract CD).
    
  • Effects of Selected Combinations of Tall Fescue Alkaloids on the Vasoconstrictive Capacity of Fescue-Naive Bovine Lateral Saphenous Veins-(Peer Reviewed Journal)
    Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Strickland, J.R. 2008. Effects of Selected Combinations of Tall Fescue Alkaloids on the Vasoconstrictive Capacity of Fescue-Naive Bovine Lateral Saphenous Veins. Journal of Animal Science. 2008. 86:1021-1028.
    
  • Ergot Alkaloid Effects on Animal Physiology-(Abstract Only)
    Strickland, J.R., Kirch, B.H., Klotz, J.L., Smith, L.L., Aiken, G.E., Flythe, M.D. 2008. Ergot Alkaloid Effects on Animal Physiology. Society for Range Management Meeting Abstracts. Published on Compact Disc, distributed at meeting; Abstract #1843. (http://srm.confex.com/srm/2008/techprogram/P1843.HTM).
    
  • USDA Kentucky Report-(Proceedings)
    Strickland, J.R., Dinkins, R.D., Aiken, G.E., Klotz, J.L., Kirch, B.H., Smith, L.L., Barnes, A.J., Waters, W.J., Bush, L.P., Brown, K.R., Matthews, J.C., Boling, J.A. 2007. Usda Kentucky report. SERA-IEG 8. pgs 159-178.
    
  • Ergovaline-induced vasoconstriction in an isolated bovine lateral saphenous vein bioassay-(Peer Reviewed Journal)
    Klotz, J.L., Bush, L.P., Smith, D.L., Shafer, W.D., Smith, L.L., Arrington, B.C., Strickland, J.R. 2007. Ergovaline-induced vasoconstriction in an isolated bovine lateral saphenous vein bioassay. Journal of Animal Science. 85:2330-2336.
    
  • Separation and Quantitation of Seven Ergot Alkaloids in Bovine Vein Tissue-(Abstract Only)
    Shafer, W.D., Smith, D.L., Smith, L.L., Klotz, J.L., Strickland, J.R. 2007. Separation and Quantitation of Seven Ergot Alkaloids in Bovine Vein Tissue. Proceedings of the ASMS Conference on Mass Spectrometry and Allied Topics, June 3-7, 2007. #ThPh-118.
    
  • Grazing High Versus Low Endophyte-Infected Tall Fescue Reduces Contractility of Bovine Lateral Saphenous Veins-(Abstract Only)
    Klotz, J.L., Brown, K.R., Matthews, J.C., Boling, J.A., Bush, L.P., Strickland, J.R. 2007. Grazing High Versus Low Endophyte-Infected Tall Fescue Reduces Contractility of Bovine Lateral Saphenous Veins. J. Anim. Sci. Vol. 85, Suppl. 1/J. Dairy Scit. Vol. 90, SUppl. 1/Poult. Sci. Vol. 86 Suppl 1. pg 12-13.
    
  • Neotyphodium Coenophialum Alters Blood Metabolites Involved in Nitrogen, Energy, and Minteral Metabolism in Growing Steers-(Abstract Only)
    Brown, K.R., Harrison, L.R., Klotz, J.L., Strickland, J.R., Boling, J.A., Matthews, J.C. 2007. Neotyphodium Coenophialum Alters Blood Metavolites Involved in Nitrogen, Energy, and Minteral Metabolism in Growing Steers. J. Anim. Sci. Vol. 85, Suppl. 1/J. Dairy Scit. Vol. 90, SUppl. 1/Poult. Sci. Vol. 86 Suppl 1. pg 418.
    
  • Ergocryptine and Ergonovine Induced Contractile Responses in Fescue Naive Bovine Lateral Saphenous Veins-(Abstract Only)
    Klotz, J.L., Kirch, B.H., Aiken, G.E., Arrington, B.C., Bush, L.P., Strickland, J.R. 2007. Ergocryptine and Ergonovine Induced Contractile Responses in Fescue Naive Bovine Lateral Saphenous Veins. J. Anim. Sci. Vol. 85, Suppl. 1/J. Dairy Scit. Vol. 90, SUppl. 1/Poult. Sci. Vol. 86 Suppl 1. pg 13.
    
  • Changes in net portal nutrient flux in response to weaning transition and ionohore supplementation in dairy calves-(Peer Reviewed Journal)
    Klotz, J.L., Heitmann, R.N. 2007. Changes in net portal nutrient flux in response to weaning transition and ionohore supplementation in dairy calves. Journal of Dairy Science. 90:1326-1339.
    
  • USDA-Kentucky Report: Forage-Animal Production Research Unit (FAPRU) Investigations: Tall Fescue Alkaloids and Toxicosis-(Proceedings)
    Strickland, J.R., Aiken, G.E., Dinkins, R.D., Klotz, J.L., Kirch, B.H., Smith, L.L., Looper, M.L., Bush, L.P., Arrington, B.C., Smith, D.L., Shafer, W.D., Schardl, C., Hesse, U. 2006. Usda-Kentucky Report: Forage-Animal Production Research Unit (FAPRU) Investigations: Tall Fescue Alkaloids and Toxicosis. SERA-IEG 8. Annual Report: pgs. 97-111.
    
  • Assessment of Vasoconstrictive Capacity of Tall Fescue Alkaloids Using Fescue Naive Lateral Saphenous Veins of Crossbreed Heifer Cattle-(Proceedings)
    Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Strickland, J.R., Arrington, B.C. 2007. Assessment of Vasoconstrictive Capacity of Tall Fescue Alkaloids Using Fescue Naive Lateral Saphenous Veins of Crossbreed Heifer Cattle. Proceedings of the 6th International Symposium on Fungal Endophytes of Grasses. Grassland Research and Practice Series No. 13:383-385.
    
  • ASSESSMENT OF VASOCONSTRICTIVE POTENTIAL OF D-LYSERGIC ACID USING AN ISOLATED BOVINE LATERAL SAPHENOUS VEIN BIOASSAY-(Peer Reviewed Journal)
    Klotz, J.L., Bush, L.P., Smith, D.L., Schafer, W.D., Smith, L.L., Vevoda, A.O., Craig, A.M., Arrington, B.C., Strickland, J.R. 2006. Assessment of vasoconstrictive potential of d-lysergic acid using an isolated bovine lateral saphenous vein bioassay. Journal of Animal Science. 84:3167-3175.
    
  • Monitoring the presence of ergot alkaloids in forage animal samples-(Abstract Only)
    Smith, D.L., Shafer, W.D., Smith, L.L., Klotz, J.L., Strickland, J.R. 2006. Monitoring the presence of ergot alkaloids in forage animal samples. American Society for Mass Spectrometry. Proceedings of the 54th ASMS Conference.
    
  • GROSS AND HISTOPATHOLOGICAL OBSERVATIONS OF LONG TERM CATHETERIZED VESSELS IN EXPERIMENTAL SHEEP-(Peer Reviewed Journal)
    Barraza, M.L., Strickland, J.R., Zepada, H., Taylor, J.B., Krehbiel, C.R., Bell, G.S., Koltz, J.L., 2006. Gross and histopathological observations of long term catheterized vessels in experimental sheep. Journal of Veterinary Medicine. 53:230-238 (2006).
    
  • Evaluation of the Vasoconstrictive Capacity of Tall Fescue Alkaloids Using Fescue Naive Bovine Lateral Saphenous Veins-(Abstract Only)
    Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Arrington, B.C., Strickland, J.R. 2006. Evaluation of the Vasoconstrictive Capacity of Tall Fescue Alkaloids Using Fescue Naive Bovine Lateral Saphenous Veins. Journal of Animal Science Supplement. 84:54.
    
  • Response of Bovine Lateral Saphenous Vein to Increasing Concentrations of Lysergic Acid and Ergovaline-(Abstract Only)
    Klotz, J.L., Arrington, B.C., Bush, L.P., Strickland, J.R. 2006. Response of Bovine Lateral Saphenous Vein to Increasing Concentrations of Lysergic Acid and Ergovaline. Journal of Animal Science Supplement. 84:53-54.
    
  • EFFECTS OF WEANING AND INOPHORE SUPPLEMENTATION ON SELECTED BLOOD METABOLITES AND GROWTH IN DAIRY CALVES-(Peer Reviewed Journal)
    Klotz, J.L., Heitmann, R.N. 2006. Effects of weaning and inophore supplementation on selected blood metabolites and growth in dairy calves. Journal of Dairy Science. 89:3587-3598.
    
  • ANNUAL PROGRESS REPORT FOR USDA-ARS-FAPRU TO SERAIEG 8 TALL FESCUE TOXICOSIS/ENDOPHYTE WORKSHOP-(Other)
    Klotz, J.L., Schafer, W.D., Smith, D.K., Smith, L.L., Arrington, B.C., Bush, L.P., Strickland, J.R., Aiken, G.E., Schardl, S., Hesse, U., Dinkins, R.D. 2005. Annual progress report for USDA-ARS-FAPRU to SERA-IEG 8 Tall Fescue Toxicosis/Endophyte Workshop. Meeting Proceedings. pgs 30-36.
    
  • Clearance of Para-Aminohippuric Acid in Wethers Consuming Locoweed-(Peer Reviewed Journal)
    Strickland, J.R., Custis, M., Ashley, A.K., Smith, L.L., Klotz, J.L., Krehbiel, C. 2005. Clearance of Para-Aminohippuric Acid in Wethers Consuming Locoweed. New Zealand Veterinary Journal. 53(5):288-292.
    
  • Effects of Limb Origin and Twenty-four Hour Storage on Contractile Response of Bovine Lateral Saphenous Vein to Norepinephrine-(Abstract Only)
    Klotz, J.L., Sevold, A., Bush, L., Strickland, J.R. 2005. Effects of Limb Origin and Twenty-four Hour Storage on Contractile Response of Bovine Lateral Saphenous Vein to Norepinephrine. Journal of Animal Science. 83:299.
    

• Projects

  Increasing Sustainability of Forage Production in Mid-South Agroecosystems In-House Appropriated (D)   Accession Number:445756

  The Roles of Forage and Phytochemicals at the Plant-Microbe-Animal Nexus for Sustainable Ruminant In-House Appropriated (D)   Accession Number:442960

  Utilizing the University of Kentucky Animal Care and Use Committee Non-Funded Cooperative Agreement (N)   Accession Number:440156

• ARS News Articles

  Connecting the Dots for Alkaloids, Toxicosis Symptoms