Research Project: Immunological and Practical Approaches to Manipulate the Ecological Niches and Reduce Foodborne Pathogens in Poultry

Location: Food and Feed Safety Research

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Linking norepinephrine production and performance to diet-induced low-grade, chronic inflammation in the intestine of broilers - (Peer Reviewed Journal)

Protected biofactors and antioxidants reduce the negative consequences of virus and cold challenge by modulating immunometabolism via changes in the interleukin-6 receptor signaling cascade in the liver - (Peer Reviewed Journal)
Perry, F., Johnson, C.N., Lahaye, L., Santin, E., Korver, D.R., Kogut, M.H., Arsenault, R.J. 2024. Protected biofactors and antioxidants reduce the negative consequences of virus and cold challenge by modulating immunometabolism via changes in the interleukin-6 receptor signaling cascade in the liver. Poultry Science. 103(9). Article 104044. https://doi.org/10.1016/j.psj.2024.104044.

Selection for high and low antibody responses to sheep red blood cells influences cytokine and chemokine expression in chicken peripheral blood leukocytes and splenic tissue - (Peer Reviewed Journal)
Swaggerty, C.L., Siegel, P.B., Honacker, C.F., Kogut, M.H., Anderson, R.C., Ashwell, C.M., Taylor, R.L. 2024. Selection for high and low antibody responses to sheep red blood cells influences cytokine and chemokine expression in chicken peripheral blood leukocytes and splenic tissue. Poultry Science. 103(9). Article 103972. https://doi.org/10.1016/j.psj.2024.103972.

Serum cytokine profile of neonatal broiler chickens infected with Salmonella Typhimurium - (Peer Reviewed Journal)
Milby-Blackledge, A., Farnell, Y., Zhao, D., Berghman, L., Laino, C., Muller, M., Byrd II, J.A., Farnell, M. 2024. Serum cytokine profile of neonatal broiler chickens infected with Salmonella Typhimurium. Frontiers in Physiology. 15. Article 1359722. https://doi.org/10.3389/fphys.2024.1359722.

How did antibiotic growth promoters increase growth and feed efficiency in poultry? - (Peer Reviewed Journal)
Miyakawa, M.E., Casanova, N.A., Kogut, M.H. 2023. How did antibiotic growth promoters increase growth and feed efficiency in poultry? Poultry Science. 103(2). Article 103278. https://doi.org/10.1016/j.psj.2023.103278.

Phenotype alterations in the cecal ecosystem involved in the asymptomatic intestinal persistence of paratyphoid Salmonella in chickens - (Peer Reviewed Journal)
Kogut, M.H., Fernandez, Miyakawa, M.E. 2023. Phenotype alterations in the cecal ecosystem involved in the asymptomatic intestinal persistence of paratyphoid Salmonella in chickens. Animals. 13. Article 2824. https://doi.org/10.3390/ani13182824.

Controlling Salmonella: strategies for feed, the farm, and the processing plant - (Peer Reviewed Journal)
Obe, T., Boltz, T., Kogut, M.H., Ricke, S.C., Brooks, L.A., Macklin, K., Peterson, A. 2023. Controlling Salmonella: strategies for feed, the farm, and the processing plant. Poultry Science. 102(12). Article 103086. https://doi.org/10.1016/j.psj.2023.103086.

Bacitracin supplementation as a growth promoter down-regulates innate and adaptive cytokines in broilers intestine - (Peer Reviewed Journal)
Dalpont, G.C., Lee, A., Bortoluzzi, C., Farnell, Y.Z., Gougoulias, C., Kogut, M.H. 2023. Bacitracin supplementation as a growth promoter down-regulates innate and adaptive cytokines in broilers intestine. Poultry. 2:411-417. https://doi.org/10.3390/poultry2030030.

Distillers dried grains with soluble and enzyme inclusion in the diet effects broilers performance, intestinal health, and microbiota composition - (Peer Reviewed Journal)
Dal Pont, G.C., Bortoluzzi, C., Rohloff, N., Farnell, Y., Pill, R., Suchodolski, J., Ceccantini, M., Eyng, C., Kogut, M.H. 2023. Distillers dried grains with soluble and enzyme inclusion in the diet effects broilers performance, intestinal health, and microbiota composition. Poultry Science. Article 102981. https://doi.org/10.1016/j.psj.2023.102981.

M2 polarization and inhibition of host cell glycolysis contributes intracellular survival of Salmonella strains in chicken macrophage HD-11 cells - (Peer Reviewed Journal)
He, L.H., Genovese, K.J., Arsenault, R.J., Johnson, C.N., Swaggerty, C.L., Byrd II, J.A., Kogut, M.H. 2023. M2 polarization and inhibition of host cell glycolysis contributes intracellular survival of Salmonella strains in chicken macrophage HD-11 cells. Microorganisms. 11(7). Article 1838. https://doi.org/10.3390/microorganisms11071838.

Impact of a blend of microencapsulated organic acids and botanicals on the microbiome of commercial broiler breeders under clinical necrotic enteritis - (Peer Reviewed Journal)
Dittoe, D., Johnson, C.N., Byrd II, J.A., Ricke, S.C., Piva, A., Grilli, E., Swaggerty, C.L. 2023. Impact of a blend of microencapsulated organic acids and botanicals on the microbiome of commercial broiler breeders under clinical necrotic enteritis. Animals. 13(10). Article 1627. https://doi.org/10.3390/ani13101627.

Effects of hops treatment on nitrogen retention, volatile fatty acid accumulations, and select microbial populations of composting poultry litter intended for use as a ruminant feedstuff - (Peer Reviewed Journal)
Castillo-Castillo, Y., Arzola-Alvarez, C., Fonseca, M., Salinas-Chavira, J., Ontiveros-Magadan, M., Hume, M.E., Anderson, R.C., Flythe, M.D., Byrd II, J.A., Ruiz-Barrera, O. 2023. Effects of hops treatment on nitrogen retention, volatile fatty acid accumulations, and select microbial populations of composting poultry litter intended for use as a ruminant feedstuff. Microorganisms. 11(4). Article 839. https://doi.org/10.3390/microorganisms11040839.

A microencapsulated feed additive containing organic acids and botanicals has a distinct effect on proliferative and metabolic related signaling in the jejunum and ileum of broiler chickens - (Peer Reviewed Journal)
Johnson, C.N., Arsenault, R.J., Piva, A., Grilli, E., Swaggerty, C.L. 2023. A microencapsulated feed additive containing organic acids and botanicals has a distinct effect on proliferative and metabolic related signaling in the jejunum and ileum of broiler chickens. Frontiers in Physiology. 14. Article 1147483. https://doi.org/10.3389/fphys.2023.1147483.

Leukocyte response to Campylobacter intra-abdominal infection in one day old leghorn chickens - (Peer Reviewed Journal)
Genovese, K.J., He, H., Swaggerty, C.L., Byrd II, J.A., Kogut, M.H. 2023. Leukocyte response to Campylobacter intra-abdominal infection in one day old leghorn chickens. Microorganisms. 11(3). Article 613. https://doi.org/10.3390/microorganisms11030613.

Addition of a protected complex of biofactors and antioxidants to breeder hen diets confers transgenerational protection against Salmonella enterica serovar Enteritidis in progeny chicks - (Peer Reviewed Journal)
Swaggerty, C.L., Malheiros, R.D., Lahaye, L., Byrd II, J.A., Genovese, K.J., He, L.H., Santin, E., Kogut, M.H. 2023. Addition of a protected complex of biofactors and antioxidants to breeder hen diets confers transgenerational protection against Salmonella enterica serovar Enteritidis in progeny chicks. Poultry Science. 102(4). Article 102531. https://doi.org/10.1016/j.psj.2023.102531.

Editorial: Functional mechanisms at the avian gut microbiome-intestinal immunity interface and its regulation of avian physiological responses - (Peer Reviewed Journal)
Kogut, M.H., Fernandez-Miyakawa, M. 2022. Editorial: Functional mechanisms at the avian gut microbiome-intestinal immunity interface and its regulation of avian physiological responses. Frontiers in Physiology. 13. Article 1063102. https://doi.org/10.3389/fphys.2022.1063102.

Development of a multistrain Nile tilapia (Oreochromis niloticus) gut microbiota-derived probiotic with antibacterial activity against fish pathogens - (Peer Reviewed Journal)

Protected biofactors and antioxidants reduce the negative consequences of virus and cold challenge while enhancing performance by modulating immunometabolism through cytoskeletal and immune signaling in the jejunum - (Peer Reviewed Journal)
Perry, F., Lahaye, L., Johnson, C., Korver, D., Kogut, M.H., Arsenault, R. 2022. Protected biofactors and antioxidants reduce the negative consequences of virus and cold challenge while enhancing performance by modulating immunometabolism through cytoskeletal and immune signaling in the jejunum. Poultry Science. 101(12). Article e102172. https://doi.org/10.1016/j.psj.2022.102172.

Novel model for chronic intestinal inflammation in chickens: (2) immunologic mechanism behind the inflammatory response - (Peer Reviewed Journal)
Dal Point, G.C., Lee, A., Bortoluzzi, C., Farnell, Y., Gougoulias, C., Kogut, M.H. 2022. Novel model for chronic intestinal inflammation in chickens: (2) immunologic mechanism behind the inflammatory response. Developmental and Comparative Immunology. 138. Article 104524. https://doi.org/10.1016/j.dci.2022.104524.

Management practices affecting lesser mealworm larvae (Alphitobius diaperinus) associated microbial community in a broiler house and after relocating with the litter into pastureland - (Peer Reviewed Journal)
Crippen, T.L., Singh, B., Anderson, R.C., Sheffield, C.L. 2022. Management practices affecting lesser mealworm larvae (Alphitobius diaperinus) associated microbial community in a broiler house and after relocating with the litter into pastureland. Frontiers in Microbiology. 13. Article 875930. https://doi.org/10.3389/fmicb.2022.875930.

Chicken-specific kinome analysis of early host immune signaling pathways in the cecum of newly hatched chicks infected with Salmonella enterica serovar Enteriditis - (Peer Reviewed Journal)
Kogut, M.H., Genovese, K.J., Byrd II, J.A., Swaggerty, C.L., He, L.H., Farnell, Y., Arsenault, R. 2022. Chicken-specific kinome analysis of early host immune signaling pathways in the cecum of newly hatched chicks infected with Salmonella enterica serovar Enteriditis. Frontiers in Cellular and Infection Microbiology. 12. Article 899395. https://doi.org/10.3389/fcimb.2022.899395.

Role of diet-microbiota interactions in precision nutrition of the chicken: facts, gaps, and new concepts - (Peer Reviewed Journal)
Kogut, M.H. 2022. Role of diet-microbiota interactions in precision nutrition of the chicken: facts, gaps, and new concepts. Poultry Science. 101(3). Article 101673. https://doi.org/10.1016/j.psj.2021.101673.

A blend of microencapsulated organic acids and botanicals reduces necrotic enteritis via specific signaling pathways in broilers - (Peer Reviewed Journal)
Swaggerty, C.L., Byrd II, J.A., Arsenault, R.J., Perry, F., Johnson, C.N., Genovese, K.J., He, H., Kogut, M.H., Piva, A., Grilli, E. 2022. A blend of microencapsulated organic acids and botanicals reduces necrotic enteritis via specific signaling pathways in broilers. Poultry Science. 101(4). Article 101753. https://doi.org/10.1016/j.psj.2022.101753.

Adult Alphitobius diaperinus microbial community during broiler production and in spent litter after stockpiling - (Peer Reviewed Journal)
Crippen, T.L., Singh, B., Anderson, R.C., Sheffield, C.L. 2022. Adult Alphitobius diaperinus microbial community during broiler production and in spent litter after stockpiling. Microorganisms. 10(1). Article 175. https://doi.org/10.3390/microorganisms10010175.

From crypts to enteroids: Establishment and characterization of avian intestinal organoids - (Peer Reviewed Journal)
Zhao, D., Farnell, M.B., Kogut, M.H., Genovese, K.J., Chapkin, R.S., Davidson, L.A., Berghman, L.R., Farnell, Y.Z. 2022. From crypts to enteroids: Establishment and characterization of avian intestinal organoids. Poultry Science. 101(3). Article 101642. https://doi.org/10.1016/j.psj.2021.101642.

Protected organic acids and essential oils for broilers raised under field conditions: Intestinal health biomarkers and cecal microbiota - (Peer Reviewed Journal)
Bortoluzzi, C., Lahaye, L., Oxford, J., Detzler, D., Eyng, C., Barbieri, N.L., Santin, E., Kogut, M.H. 2021. Protected organic acids and essential oils for broilers raised under field conditions: Intestinal health biomarkers and cecal microbiota. Frontiers in Physiology. 12. Article 722339. https://doi.org/10.3389/fphys.2021.722339.

Evaluation of sodium bisulfate on reducing Salmonella Heidelberg biofilm and colonization in broiler crops and ceca - (Peer Reviewed Journal)
Pineda, M., Byrd II, J.A., Genovese, K.J., Farnell, Y.Z., Zhao, D., Wang, X., Milby, A., Farnell, M.B. 2021. Evaluation of sodium bisulfate on reducing Salmonella Heidelberg biofilm and colonization in broiler crops and ceca. Microorganisms. 9(10). Article 2047. https://doi.org/10.3390/microorganisms9102047.

Heat stress and feed restriction distinctly affect performance, carcass and meat yield, intestinal integrity and inflammatory (chemo) cytokines in broiler chickens - (Peer Reviewed Journal)
Emami, N., Greene, E., Kogut, M.H., Dridi, S. 2021. Heat stress and feed restriction distinctly affect performance, carcass and meat yield, intestinal integrity and inflammatory (chemo) cytokines in broiler chickens. Frontiers in Physiology. 12. Article 707757. https://doi.org/10.3389/fphys.2021.707757.

Determination of antimicrobial resistance patterns in Salmonella from commercial poultry as influenced by microbiological culture and antimicrobial susceptibility testing methods - (Peer Reviewed Journal)
Wang, X., Chaney, E.W., Pavlidis, H.O., Mcginnis, J.P., Byrd II, J.A., Farnell, Y.Z., Johnson, T.J., Mcelroy, A.P., Farnell, M.B. 2021. Determination of antimicrobial resistance patterns in Salmonella from commercial poultry as influenced by microbiological culture and antimicrobial susceptibility testing methods. Microorganisms. 9(6). Article 1319. https://doi.org/10.3390/microorganisms9061319.