Research Project: Systems Biology Approaches to Develop Medical Countermeasures to Detect, Prevent, and Control Poultry Production Viral Diseases

Location: Endemic Poultry Viral Diseases Research

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Whole genomic constellation of avian reovirus strains isolated from broilers with arthritis in North Carolina, USA - (Peer Reviewed Journal)
Nour, I., Alvarez Narvaez, S., Harrell, T.L., Conrad, S.J., Mohanty, S.K. 2023. Whole genomic constellation of avian reovirus strains isolated from broilers with arthritis in North Carolina, USA. Viruses. 15:2191. https://doi.org/10.3390/v15112191.

Whole genome sequencing of infectious bursal disease viruses isolated from a Californian outbreak unravels the underlying virulence markers and highlights positive selection incidence - (Peer Reviewed Journal)
Nour, I., Blakey, J.R., Alvarez Narvaez, S., Mohanty, S.K. 2023. Whole genome sequencing of infectious bursal disease viruses isolated from a Californian outbreak unravels the underlying virulence markers and highlights positive selection incidence. Viruses. 15(10):2044. https://doi.org/10.3390/v15102044.

Optimizing the conditions for whole-genome sequencing of avian reoviruses - (Peer Reviewed Journal)
Alvarez Narvaez, S., Harrell, T.L., Oluwayinka, O., Sellers, H.S., Khalid, Z., Hauck, R., Chowdhury, E.U., Conrad, S.J. 2023. Optimizing the conditions for whole-genome sequencing of avian reoviruses. Viruses. 15(9):1938. https://doi.org/10.3390/v15091938.

Newcastle disease virus (NDV) recombinant expressing Marek’s disease virus (MDV) glycoprotein B protects chickens against MDV and NDV challenges - (Peer Reviewed Journal)
He, L., Spatz, S.J., Dunn, J.R., Yu, Q. 2023. Newcastle disease virus (NDV) recombinant expressing Marek’s disease virus (MDV) glycoprotein B protects chickens against MDV and NDV challenges. Vaccine. 41(40):5884-5891. https://doi.org/10.1016/j.vaccine.2023.08.038.

Viral proteogenomic and expression profiling during productive replication of a skin-tropic herpesvirus in the natural host - (Peer Reviewed Journal)
Volkening, J.D., Spatz, S.J., Ponnuraj, N., Akbar, H., Arrington, J.V., Vega-Rodriguez, W., Jaronsinski, K.W. 2023. Viral proteogenomic and expression profiling during productive replication of a skin-tropic herpesvirus in the natural host. PLoS Pathogens. 19(6):e1011204. https://doi.org/10.1371/journal.ppat.1011204.

Rapid construction of a reverse genetics rescue system for distinct Newcastle disease virus genotypes - (Peer Reviewed Journal)
Yu, Z., Zhang, Y., Li, Z., Yu, Q., Jia, Y., Yu, C., Chen, J., Chen, S., He, L. 2023. Rapid construction of a reverse genetics rescue system for distinct Newcastle disease virus genotypes. Frontiers in Veterinary Science. 10. Article 1178801. https://doi.org/10.3389/fvets.2023.1178801.

Evaluation of Newcastle disease virus LaSota strain attenuated by codon pair deoptimization of the HN and F genes for in ovo vaccination - (Peer Reviewed Journal)
Eldemery, F., Ou, C., Kim, T.N., Spatz, S.J., Dunn, J.R., Silva, R.F., Yu, Q. 2022. Evaluation of Newcastle disease virus LaSota strain attenuated by codon pair deoptimization of the HN and F genes for in ovo vaccination. Veterinary Microbiology. 277:109625. https://doi.org/10.1016/j.vetmic.2022.109625.

Rhesus rotavirus receptor-binding site affects high mobility group box 1 release, altering the pathogenesis of experimental biliary atresia - (Peer Reviewed Journal)
Mohanty, S.K., Donnelly, B., Temple, H., Mowery, S., Poling, H.M., Meller, J., Malik, A., Mcneal, M., Tiao, G. 2022. Rhesus rotavirus receptor-binding site affects high mobility group box 1 release, altering the pathogenesis of experimental biliary atresia. Hepatology Communications. 6(10):2702-2714. https://doi.org/10.1002/hep4.2024.

Quantitative regulation of the thermal stability of enveloped virus vaccines by surface charge engineering to prevent the self-aggregation of attachment glycoproteins - (Peer Reviewed Journal)
Shang, Y., Li, L., Zhang, T., Luo, Q., Yu, Q., Zeng, Z., Li, L., Jia, M., Tang, G., Fan, S. 2022. Quantitative regulation of the thermal stability of enveloped virus vaccines by surface charge engineering to prevent the self-aggregation of attachment glycoproteins. PLoS Pathogens. 18(6). Article e1010564. https://doi.org/10.1371/journal.ppat.1010564.

T-bet deficiency attenuates bile duct injury in experimental biliary atresia - (Peer Reviewed Journal)
Mohanty, S.K., Donnelly, B., Temple, H., Bondoc, A., Mcneal, M., Tiao, G. 2021. T-bet deficiency attenuates bile duct injury in experimental biliary atresia. Cells. 10(12):3461. https://doi.org/10.3390/cells10123461.