Author
Lee, Charles | |
Wagschal, Kurt | |
PAAVOLA, CHAD - National Aeronautics And Space Administration (NASA) |
Submitted to: Meeting Abstract
Publication Type: Abstract Only Publication Acceptance Date: 5/21/2015 Publication Date: 6/7/2015 Citation: Lee, C.C., Wagschal, K.C., Paavola, C. 2015. Enzyme nanoassemblies for biomass conversion. Meeting Abstract. Gordon Research Conference Abstracts, 1(10). Interpretive Summary: Technical Abstract: Biomass represents a vast resource for the production of the world’s fuel and chemical feedstock needs. The use of enzymes to effect these bioconversions offers an alternative that is potentially more specific and environmentally-friendly than harsher chemical methodologies. Some species of anaerobic bacteria produce enzyme complexes called cellulosomes which are particularly effective in hydrolyzing biomass into the constituent monomeric sugars. Inspired by this model, we have designed an artificial cellulosome-like scaffold upon which we can create complexes incorporating a wide variety of enzymes. Using these customized complexes called rosettazymes, we have demonstrated enhanced biomass hydrolysis and bioconversion into value-added chemical feedstocks. In this presentation, we describe this work which is supported by NIFA grant #2012-67021-20063. |