Complete genome sequence of Campylobacter jejuni strain 12567 a livestock-associated clade representative

Authors: SACHER, JESSICA - University Of Alberta; Yee, Emma; SZYMANSKI, CHRISTINE - University Of Alberta; Miller, William - Bill

Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 5/7/2018
Publication Date: 6/14/2018
Citation: Sacher, J.C., Yee, E., Szymanski, C.M., Miller, W.G. 2018. Complete genome sequence of Campylobacter jejuni strain 12567 a livestock-associated clade representative. Genome Announcements. 6(24):e00513-18. https://doi.org/10.1128/genomeA.00513-18.
DOI: https://doi.org/10.1128/genomeA.00513-18

Interpretive Summary: Campylobacter jejuni is a human gastrointestinal pathogen that causes diarrheal disease worldwide. C. jejuni naturally colonizes chickens, and thus human infections commonly arise upon consumption and handling of poultry products. The coating of surface structures with various and variable sugars is important for C. jejuni persistence in poultry; further understanding of the mechanisms leading to such modification can drive strategies to reduce the presence of C. jejuni in food animals, especially poultry. We have completed the genome sequence of C. jejuni 12567, a poultry-derived livestock-associated isolate. Strain 12567 is a relatively poorly-studied isolate whose surface sugars have been disproportionately well characterized. Livestock-associated strains are thought to more efficiently colonize chickens by the addition of particular sugars. As a strain whose sugars have been well analyzed but whose genome has not yet been made available, the genome sequence of 12567 provides a resource for studying sugar modification mechanisms in C. jejuni.

Technical Abstract: We report the complete genome sequence of the Campylobacter jejuni strain 12567, a member of a C. jejuni livestock-associated clade that expresses glycoconjugates linked to improved gastrointestinal tract persistence.