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ARS Home » Southeast Area » Athens, Georgia » U.S. National Poultry Research Center » Exotic & Emerging Avian Viral Diseases Research » Research » Publications at this Location » Publication #372446

Research Project: Intervention Strategies to Predict, Prevent and Control Disease Outbreaks Caused by Emerging Strains of Virulent Newcastle Disease Viruses

Location: Exotic & Emerging Avian Viral Diseases Research

Title: A 24-year-old sample contributes the complete genome sequence of fowl aviadenovirus D from the United States

Author
item GORAICHUK, IRYNA - Consultant
item DAVIS, JAMES - University Of Georgia
item KULKARNI, ARUN - Georgia Poultry Laboratory Network
item Afonso, Claudio
item Suarez, David

Submitted to: Microbiology Resource Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 12/2/2020
Publication Date: 1/7/2021
Citation: Goraichuk, I.V., Davis, J.F., Kulkarni, A.B., Afonso, C.L., Suarez, D.L. 2021. A 24-year-old sample contributes the complete genome sequence of fowl aviadenovirus D from the United States. Microbiology Resource Announcements. 10:(1):e01211-20. https://doi.org/10.1128/MRA.01211-20.
DOI: https://doi.org/10.1128/MRA.01211-20

Interpretive Summary: Fowl aviadenovirus (FAdV) are large DNA viruses that only ireported to infect avian species exclusively. FAdVs have been categorized into five species (FAdV-A to FAdV-E) on the basis of their genome structure and further divided into 12 serotypes, based on a cross-neutralization test. FAdVs are widely distributed and cause varying degrees of associated clinical disease. Some species of FAdVs could cause inclusion body hepatitis, hepatitis-hydropericardium syndrome, adenoviral gizzard erosions, and possibly hypoglycemia and spiking mortality syndrome in chickens. To date, only partial genomes of the FAdV-D from the U.S. are available in public databases. In this study, we report the first complete genome of FAdV-D isolated from the United States.

Technical Abstract: Here, we report the complete genome sequence of fowl aviadenovirus D (FAdV-D) isolated from a preserved 24-year-old pancreas sample of a broiler chicken embryo. The results of the sequence showed that the viral genome is 44,079 bp long.