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ARS Home » Southeast Area » Athens, Georgia » U.S. National Poultry Research Center » Poultry Microbiological Safety and Processing Research Unit » Research » Publications at this Location » Publication #378178
Research Project: Novel Pre-harvest Interventions and Alternatives to Antibiotics to Reduce Foodborne Pathogens

Location: Poultry Microbiological Safety and Processing Research Unit

Title: Draft genome sequences of two campylobacter jejuni strains that show significantly different colonization potentials in chickens

Author
item SUNG, KIDON - Us Food & Drug Administration (FDA)
item KHAJANCHI, BIJAY - Us Food & Drug Administration (FDA)
item HEITT, KELLI - Us Food & Drug Administration (FDA)
item Line, John
item KHAN, SAEED - Us Food & Drug Administration (FDA)

Submitted to: Microbiology Resource Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 9/16/2020
Publication Date: 10/8/2020
Citation: Sung, K., Khajanchi, B.K., Heitt, K.L., Line, J.E., Khan, S. 2020. Draft genome sequences of two campylobacter jejuni strains that show significantly different colonization potentials in chickens. Microbiology Resource Announcements. 9(41). Article e00687-20. https://doi.org/10.1128/MRA.00687-20.
DOI: https://doi.org/10.1128/MRA.00687-20

Interpretive Summary: Campylobacter species are considered one of the leading causes of bacterial gastrointestinal disease in humans in the United States and other parts of the globe. Poultry is a natural reservoir for C. jejuni, which is capable of colonizing the chicken in the intestinal tract. Handling raw chicken meat or eating insufficiently cooked chicken is believed to be a significant risk factor of Campylobacter infection. An individual poultry housing challenge model was used to recover C. jejuni isolates (a robust colonizer, A74/C, and a poor colonizer, A74/O) exhibiting differing colonization levels after oral challenge. Here we report the draft genome sequences of robust (A74/C_24-3) and poor (A74/O_2-2) chicken-colonizing Campylobacter jejuni isolates. Whole genome sequence analyses of these isolates will be helpful to facilitate further studies to identify genetic factors used in chicken colonization.

Technical Abstract: Here we report the draft genome sequences of robust (A74/C_24-3) and poor (A74/O_2-2) chicken-colonizing Campylobacter jejuni isolates. Whole genome sequence analyses of these isolates will be helpful to facilitate further studies to identify genetic factors used in chicken colonization.