Alternatives to Antibiotics (ATA)

Welcome Address - Bernard Vallat, Directeur Général,
World Organisation for Animal Health (OIE), France

Program Review - Objectives and Expected Outcomes
Cyril G Gay, National Program Leader
Agricultural Research Service (ARS), USDA, USA

Keynote Presentation
New approaches to address antimicrobial resistance in animals
Julian Davies, Professor
University of British Columbia, Canada

Antimicrobials in Animal Health - Lessons from Nature
Frank Blecha
College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA

Avian cathelicidins: paradigms for the development of anti-infectives
Henk P. Haagsman
Department of Infectious Diseases and Immunology, Utrecht University, The Netherlands

Animal-derived Antimicrobial Peptides and Swine Health
Yizhen Wang
Nutrition and Swine Immunology Laboratory, Feed Science Institute, Zhejiang University, China

Prebiotics and Probiotics in Animal Production: Present Status and Future Perspectives
Richard Ducatelle
Ghent University, Salisburylaan 133, Merelbeke, Belgium

Heavy metals as alternatives to antibiotics: Panacea or Pandora´s Box?
H. Morgan Scott
Diagnostic Medicine, Pathobiology, Kansas State University, Manhattan, Kansas, USA

Bacteriophages the alternatives to antibiotics for animal feed
Jae-Won Kim
CJ Research Institute of Biotechnology, CJ Cheiljedang, Seoul, Republic of Korea

Session 1 Expert Panel Discussion: Review novel alternatives to antibiotics from nature and discuss what is needed to develop them

Selective modulators of innate immunity for anti-infective therapy to replace or supplement antibiotics
Robert E.W. Hancock, University of British Columbia, Canada

Novel anti-infective molecule from innate immune cells as an antibiotic-alternative to control infections caused by Apicomplexa
Hyun Lillehoj, Agricultural Research Service, Beltsville, MD, USA

Control and Prevention of Antibiotic-Resistant Infections by a Host Defense Peptide through Modulation of Innate Immunity
Guolong Zhang
Oklahoma State University, Stillwater, OK, USA

Biotherapeutics as Alternatives to Antibiotics: Effect of IFN-α and G-CSF on Innate and Adaptive Immunity in Swine
Susan L. Brockmeier
Agricultural Research Service, Ames, IA, USA

Session 2 Expert Panel Discussion: Review novel immune intervention strategies to replace or complement antibiotics for disease prevention and treatment and discuss what is needed to develop them.

The role of the microbiota in enteric diseases and allergies
Brett Finlay
University of British Columbia, Canada

The ruminal microbiome and animal health
John Wallace
Rowett Institute of Nutrition and Health, U.K.

The ruminal virome
Bryan A. White,
University of Illinois, U.S.A.

The chicken intestinal microbiome as a target for improving productivity
Margie Lee
University of Georgia, U.S.A.

Impact of age and intestinal microbiota on the expression of avian defensins in the chicken gut
Anne-Christine Lalmanach
INRA, UMR 1282 Infectiologie et Santé Publique, Nouzilly, France

Session 3 Expert Panel Discussion: Review novel technologies derived from the gut microbiome and discuss what is needed to develop them

SESSION 4
Alternatives to Antibiotics to Promote Growth in Livestock,
Poultry, and Aquaculture Production

Chairs: Filip Van Immerseel, University of Ghent, Belgium
Sergio Calsamiglia Blancafort, University of Barcelona, Spain

Looking outside the box: Present and future perspective for alternatives to antimicrobial growth promoters in livestock and poultry
David Bravo
Pancosma, Switzerland

Alternatives to antibiotics as growth promotants for dairy and beef cattle: Mechanisms of action and field performance
Sergio Calsamiglia Blancafort
University of Barcelona, Spain

Intestinal Microbiota Associated with High Feed Conversion Efficiency in Chickens
Robert J. Moore
Australian Animal Health Laboratory, CSIRO Livestock Industries, Geelong, Australia

Cinnamaldehyde Enhances In Vitro Parameters of Immunity and Augments In Vivo Protection Against Avian Coccidiosis
Yeong Ho Hong
University, Anseong, South Korea

Effect of Dietary Protein and Protease Supplementation on Performance and Gut Health of Broiler Chicks
Pierre Buttin
Novus Europe, Avenue Marcel Thiry, Brussels, Belgium

Identification of Bile Salt Hydrolase Inhibitors, Promising Alternative to Antibiotic Growth Promoters
Jun Lin
University of Tennessee, Knoxville, TN, USA

Session 4 Expert Panel Discussion: Review alternatives to antibiotics for growth promotion and discuss what is needed to develop them

FDA´s innovation initiative to evaluate novel emerging technologies and international cooperation in the area of innovation
Steve Vaughn
Director, Office of New Animal Drug Evaluation, Center for Veterinary Medicine, FDA, Silver Spring, MD, U.S.A.

European approach to authorization of novel technologies with particular emphasis on alternatives to antibiotics
David MacKay
Head of Veterinary Medicines and Product Data Management, European Medicine Agency, Brussels, EU

National approach in China to authorization of alternatives to antibiotics
Huiyi Cai,
Institute of Feed Research, Chinese Academy of Agricultural Sciences, No.12 Zhongguancun Nandajie Beijing, China

Challenges of gaining regulatory approval in the different regions when moving new molecules from discovery to production
Marike Dussault
Director, Regulatory Affairs & Pharmacovigilance
Pfizer Animal Health, Canada

Seeking regulatory approval for a claim new to regulatory science - "This product reduces the use of antibiotics"
Octavi Panyella
Regional Regulatory Coordinator, Lohmann Animal Health GmbH, Spain

Session 5 Expert Panel Discussion: Review regulatory pathways and discuss industry needs to support the development of alternatives to antibiotics

Conclusion and Next Steps
Cyril G Gay National Program Leader, Animal Production and Protection, Agricultural Research Service, USDA, Beltsville, MD, USA