Alternatives to Antibiotics (ATA)

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Invited Presentations

Program Review

• SYMPOSIUM OBJECTIVES AND EXPECTED OUTCOMES
  Cyril G. Gay
  Agricultural Research Service, USDA, Beltsville, MD, USA

Keynote Presentation

• TOWARDS A NEW AGE OF ANTIMICROBIAL DISCOVERY
  Julian Davies
  University of British Columbia, Canada

Session 1
Alternatives to Antibiotics: Lessons from Nature

• 1.1   ANTIMICROBIALS IN ANIMAL HEALTH: LESSONS FROM NATURE
  Frank Blecha
  College of Veterinary Medicine, Kansas State University, Manhattan, Kansas, USA

• 1.2 AVIAN CATHELICIDINS: PARADIGMS FOR THE DEVELOPMENT OF ANTIINFECTIVES
  Henk P. Haagsman
  Department of Infectious Diseases and Immunology, Utrecht University, The Netherlands

• 1.3 ANIMAL-DERIVED ANTIMICROBIAL PEPTIDES AND SWINE HEALTH
  Yizhen Wang, Nutrition and Swine Immunology Laboratory, Feed Science Institute,
  Zhejiang University, China

• 1.4 PREBIOTICS AND PROBIOTICS IN ANIMAL PRODUCTION: PRESENT STATUS AND FUTURE PERSPECTIVES
  Richard Ducatelle
  Department of Pathology, Bacteriology and Avian Medicine, Ghent University, Merelbeke, Belgium

• 1.5 HEAVY METALS AS ALTERNATIVES TO ANTIBIOTICS: PANACEA OR PANDORA'S BOX?
  H. Morgan Scott, Diagnostic Medicine, Pathobiology, Kansas State University, Manhattan, Kansas, USA

• 1.6   BACTERIOPHAGES: THE ALTERNATIVES TO ANTIBIOTICS FOR ANIMAL FEEDS
  Jae-Won Kim
  CJ Research Institute of Biotechnology, CJ Cheiljedang, Seoul, Republic of Korea

Session 2
Immune Modulation Approaches to Enhance Disease
Resistance and Treat Animal Infections

• 2.1 SELECTIVE MODULATORS OF INNATE IMMUNITY FOR ANTI-INFECTIVE THERAPY TO SUPPLEMENT OR REPLACE ANTIBIOTICS
  R.E.W. (Bob) Hancock
  Centre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, BC, Canada

• 2.2 NOVEL ANTI-INFECTIVE MOLECULE FROM INNATE IMMUNE CELLS AS AN ANTIBIOTIC-ALTERNATIVE TO CONTROL INFECTIONS CAUSED BY APICOMPLEXA
  Hyun Lillehoj
  Agricultural Research Service, USDA, Beltsville, MD, USA

• 2.3 CONTROL AND PREVENTION OF ANTIBIOTIC-RESISTANT INFECTIONS BY A HOST DEFENSE PEPTIDE THROUGH MODULATION OF INNATE IMMUNITY
  Guolong Zhang
  Oklahoma State University, Stillwater, OK, USA

• 2.4 EVALUATION OF AN INTERLEUKIN-2 TREATMENT FOR PREVENTION OF INTRAMAMMARY INFECTIONS IN COWS AFTER CALVING
  Massimo Amadori
  Laboratory of Cellular Immunology, Istituto Zooprofilattico Sperimentale della Lombardia e dell" Emilia-Romagna, Brescia, Italy

• 2.5 BIOTHERAPEUTICS AS ALTERNATIVES TO ANTIBIOTICS: EFFECTS OF IFN-α and G-CSF ON INNATE AND ADAPTIVE IMMUNITY IN SWINE
  Susan L. Brockmeier
  National Animal Disease Center, Agricultural Research Service, USDA, Ames, IA, USA

   

Session 3
The Gut Microbiome and Immune Development, Health and
Disease

• 3.2 THE RUMINAL MICROBIOME AND ANIMAL HEALTH
  R. John Wallace
  Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, UK

  3.3 THE RUMINAL VIROME
  Bryan A. White
  Department of Animal Sciences, University of Illinois, Urbana, IL, USA

  3.4 THE CHICKEN INTESTINAL MICROBIOME AS A TARGET FOR IMPROVING PRODUCTIVITY
  Margie Lee
  Poultry Diagnostic and Research Center, Department of Population Health, The University of Georgia, Athens, GA, USA

• 3.5 IMPACT OF AGE AND INTESTINAL MICROBIOTA ON THE EXPRESSION OF AVIAN DEFENSINS IN THE CHICKEN GUT
  Anne-Christine Lalmanach
  INRA, UMR 1282 Infectiologie et Santé Publique, Nouzilly, France

Session 4
Alternatives to Antibiotics to Promote Growth in Livestock,
Poultry, and Aquaculture Production

• 4.1 PERSPECTIVES FROM OUTSIDE THE BOX: THE USE OF HYTONUTRIENTS FOR OPTIMIZING GUT HEALTH AND PRODUCTIVE EFFICIENCY OF LIVESTOCK AND POULTRY ANIMALS
  David Bravo
  Pancosma, Switzerland

  4.2 ALTERNATIVES TO ANTIBIOTICS AS GROWTH PROMOTANTS FOR DAIRY AND BEEF CATTLE: MECHANISMS OF ACTION AND FIELD PERFORMANCE
  Sergio Calsamiglia Blancafort, University of Barcelona, Spain

• 4.3 INTESTINAL MICROBIOTA ASSOCIATED WITH HIGH FEED CONVERSION EFFICIENCY IN CHICKENS
  Robert J. Moore 1,4, Stuart E. Denman 2, Mark S. Geier3,4, and Dragana Stanley1,4
  1Australian Animal Health Laboratory, CSIRO Livestock Industries, Geelong, Victoria 3220, Australia

• 4.4 CINNAMALDEHYDE ENHANCES IN VITRO PARAMETERS IF IMMUNITY AND AUGMENTS IN VIVO PROTECTION AGAINST AVIAN COCCIDIOSIS
  Yeong Ho Hong, Chung Ang University, Anseong, South Korea

• 4.5 EFFECT OF DIETARY PROTEIN AND PROTEASE SUPPLEMENTATION ON PERFORMANCE AND GUT HEALTH OF BROILER CHICKS
  Pierre Buttin
  Novus Europe, Brussels, Belgium

  4.6 IDENTIFICATION OF BILE SALT HYDROLASE INHIBITORS, PROMISING ALTERNATIVE TO ANTIBIOTIC GROWTH PROMOTORS
  Jun Lin, Department of Animal Science, University of Tennessee, Knoxville, Tennessee, USA

Session 5
Regulatory Pathways to Enable the Licensing of Alternatives to Antibiotics

• 5.1 FDA’S INNOVATION INITIATIVE TO EVALUATE NOVEL EMERGING TECHNOLOGIES AND INTERNATIONAL COOPERATION IN THE AREA OF INNOVATION
  Steven D. Vaughn, DVM
  Office of New Animal Drug Evaluation, Center for Veterinary Medicine, U.S. Food and Drug Administration, Rockville, Maryland, USA

  5.2 EUROPEAN APPROACH TO AUTHORIZATION OF NOVEL TECHNOLOGIES WITH PARTICULAR EMPHASIS ON ALTERNATIVES TO ANTIBIOTICS
  David MacKay, Head of Veterinary Medicines and Product Data Management, European Medicine Agency, Brussels, EU

• 5.3 APPROACH TO AUTHORIZATION OF NOVEL TECHNOLOGIES ON ALTERNATIVES TO ANTIBIOTICS IN CHINA
  Huiyi Cai
  Institute of Feed Research, Chinese Academy of Agricultural Sciences, No.12
  Zhongguancun Nandajie Beijing, China

• 5.4 ENSURING ACCESS TO INNOVATIVE THERAPIES: THE CHALLENGES OF MOVING A NEW MOLECULE FROM DISCOVERY TO PRODUCTION AND THROUGH REGULATORY APPROVAL
  Marike Dussault
  Pfizer Animal Health, Kirkland, Quebec, Canada

  5.5 SEEKING REGULATORY APPROVAL FOR A CLAIM NEW TO REGULATORY SCIENCE: THIS PRODUCT REDUCES THE USE OF ANTIBIOTICS
  Octavi Panyella
  Lohmann Animal Health, Granollers, Barcelona, Spain

Selected Presentations from Posters

• 3.13 SUCCESSFUL CONTROL OF SALMONELLA AND A MINIMIZED USE OF ANTIBIOTICS IN SWEDISH BROILER PRODUCTION BY LONG TERM IMPLEMENTATION OF DISEASE PREVENTATIVE METHODS WITH SPECIAL REFERENCE TO THE USE OF COMPETITIVE EXCLUSION (CE)
  Martin Wierup
  Department  of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural, Uppsala, Sweden

Conclusions and Next Steps

• Conclusions and Next Steps
  Cyril G. Gay
  Agricultural Research Service, USDA, Beltsville, MD, USA

This Year's Sponsors