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Laxmi Yeruva (PhD)
Arkansas Children's Nutrition Center
Research Leader

Phone: (501) 364-2419
Fax: (501) 364-2403

(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)

Projects
Early Life Factors and Microbiota Impact on Healthy Development
In-House Appropriated (D)
  Accession Number: 445369
Research to Understand How Maternal-Child Nutrition and Physical Activity Optimize Health and Development
Non-Funded Cooperative Agreement (N)
  Accession Number: 440470
Utilizing the University of Arkansas Medical Sciences Animal Care and Use Committee and the Institutional Biosafety Committee
Non-Funded Cooperative Agreement (N)
  Accession Number: 441566
Network Service Agreement for ARS - Nutrition Center Location
Non-Funded Cooperative Agreement (N)
  Accession Number: 444104
Dietary and Physical Activity Influences on Infant/Child/Adolescent/Maternal Health and Development
Non-Assistance Cooperative Agreement (S)
  Accession Number: 439549
Impact of Prenatal and Postnatal Factors on Mother and Child Health
Non-Assistance Cooperative Agreement (S)
  Accession Number: 441948
Impact of Prenatal and Postnatal Factors on Mother and Child Health
Non-Assistance Cooperative Agreement (S)
  Accession Number: 443495
Impact of Prenatal and Postnatal Factors on Mother and Child Health
Non-Assistance Cooperative Agreement (S)
  Accession Number: 444102
Early Life Factors and Microbiota Impact on Healthy Development
Non-Assistance Cooperative Agreement (S)
  Accession Number: 445913
Dietary and Physical Activity Influences on Infant/Child/ Adolescent/Maternal Health and Development
Non-Assistance Cooperative Agreement (S)
  Accession Number: 447085
Pediatric Physical Activity, Sleep, and Nutrition Impacting Cardiometabolic Health
Non-Assistance Cooperative Agreement (S)
  Accession Number: 447269
Nutritional Determinants of Child Health
Non-Assistance Cooperative Agreement (S)
  Accession Number: 447272
Mechanisms by which Nutrition During Critical Windows of Development Programs Cardiometabolic, Musculoskeletal and Gut Health
Non-Assistance Cooperative Agreement (S)
  Accession Number: 447273

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Beyond Nutrition: Human Milk Metals and Metalloids Shape Infant Microbiota - (Peer Reviewed Journal)
SARS-CoV-2 infection-induces human milk antibodies capable of mediating multiple functional activities Reprint Icon - (Peer Reviewed Journal)
Sheehan, J., Andres, A., Yeruva, V., Ramsay, A. 2024. SARS-CoV-2 infection-induces human milk antibodies capable of mediating multiple functional activities. Clinical Nutrition Open Science. https://doi.org/10.1016/j.nutos.2024.10.009.
Associations between maternal microbiome, metabolome and incidence of low-birth weight in Guatemalan participants from Women First Trial - (Peer Reviewed Journal)
Maternal immune cell gene expression associates with maternal gut microbiome, milk composition and infant gut microbiome - (Peer Reviewed Journal)
Novel odd-chain cyclopropane fatty acids: detection in the mammalian lipidome and uptake by hepatosplanchnic tissues - (Peer Reviewed Journal)
Infant microbiota communities and HMO supplementation independently and synergistically shape metabolite production and immune responses in healthy mice - (Peer Reviewed Journal)
Microbiome and Metabolism Research Unit: Bench to Community - (Abstract Only)
Role of animal and plant protein on child health outcomes - (Book / Chapter)
Maternal and postnatal factors role on child health and development: lessons learned from animal models and clinical studies - (Abstract Only)
Apiaceous Vegetables Improved Gut Dysbiosis Induced by Dextran Sodium Sulfate in mice consuming Total Western Diet - (Abstract Only)
Single-cell RNA sequencing reveals that breastfeeding shapes IL-4 and IL-13 signaling in neonatal peripheral blood mononuclear cells. - (Abstract Only)
Maternal immune cell gene expression during gestation associates with infant gut microbiota composition - (Abstract Only)
Human milk oligosaccharides and Bifidobacteria infantis interactively shape mouse splenic immune responses. - (Abstract Only)
Effects of early life stress on skeletal health - (Abstract Only)
Microbiota of infants consuming secretors or non-secretors mothers milk impacts gut and immune system in mice Reprint Icon - (Peer Reviewed Journal)
Gurung, M., Schlegel, B., Rajasundaram, D., Fox, R., Bode, L., Lindemann, S.R., Leroith, T., Read, Q.D., Simecka, C., Carol, L., Andres, A., Yeruva, V. 2024. Microbiota of infants consuming secretors or non-secretors mothers milk impacts gut and immune system in mice. mSystems. 9(4). Article e00294-24. https://doi.org/10.1128/msystems.00294-24.
Nutrition is Medicine: key players in healthy development - (Abstract Only)
Colonic epithelial hypoxia remains constant during the progression of diabetes in male UC Davis Type-2 Diabetes Mellitus Rats Reprint Icon - (Peer Reviewed Journal)
Piccolo, B., Graham, J.L., Tabor-Simecka, L., Randolph, C.E., Moody, B., Robeson, M.S., Kang, P., Fox, R., Lan, R., Pack, L., Worford, N., Yeruva, V., Leroith, T., Stanhope, K., Havel, P.J. 2024. Colonic epithelial hypoxia remains constant during the progression of diabetes in male UC Davis Type-2 Diabetes Mellitus Rats. BMJ Open Diabetes Research & Care. 12(2). Article 003813. https://doi.org/10.1136/bmjdrc-2023-003813.
The Role of Early-Life Gut Mycobiome on Child Health Reprint Icon - (Peer Reviewed Journal)
Rodriguez, K.A., Gurung, M., Talatala, R., Rearick, J.R., Ruebel, M., Stephens, K.E., Yeruva, V. 2024. The Role of Early-Life Gut Mycobiome on Child Health. Advances in Nutrition. 15(3):100185. https://doi.org/10.1016/j.advnut.2024.100185.
Human milk miRNAs associate to maternal dietary nutrients, milk microbiota, infant gut microbiota and body mass index Reprint Icon - (Peer Reviewed Journal)
Yeruva, V., Mulakala, B.K., Rajasundaram, D., Gonzalez, S., Cabrera-Rubio, R., Martinez-Costa, C., Collado, M. 2023. Human milk miRNAs associate to maternal dietary nutrients, milk microbiota, infant gut microbiota and body mass index. Clinical Nutrition. 42(12):2528-2539. https://doi.org/10.1016/j.clnu.2023.10.011.
Sustainable Food Systems Lead To Healthy Life - (Abstract Only)
The nutritional immunology across the life span Reprint Icon - (Review Article)
Saame Raza, S., Crott, J., Comstock, S., Yeruva, V., Davis, T.A. 2023. The nutritional immunology across the life span. Journal of Nutrition. https://doi.org/10.1016/j.tjnut.2023.06.008.
Evaluation of a plant-based infant formula containing almonds and buckwheat on gut microbiota composition, intestine mor-phology, metabolic and immune markers in a neonatal piglet model Reprint Icon - (Peer Reviewed Journal)
Gurung, M., Rosa, F., Yelvington, B., Terry, N., Read, Q.D., Piccolo, B., Moody, B., Tripp, P., Pittman, H., Fay, B., Ross, T., Sikes, J., Flowers, J., Fox, R., Yoseph, F., Yeruva, V., Leroith, T., Talatala, R. 2023. Evaluation of a plant-based infant formula containing almonds and buckwheat on gut microbiota composition, intestine mor-phology, metabolic and immune markers in a neonatal piglet model. Nutrients. 15(2):383. https://doi.org/10.3390/nu15020383.
Human milk oligosaccharides impact cellular and inflammatory gene expression and immune response Reprint Icon - (Peer Reviewed Journal)
Rosa, F., Sharma, A.K., Gurung, M., Casero, D., Matazel, K., Bode, L., Simecka, C., Elolimy, A.A., Tripp, P., Randolph, C., Hand, T.W., Williams, K.D., Leroith, T., Fox, R., Yeruva, V. 2022. Human milk oligosaccharides impact cellular and inflammatory gene expression and immune response. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2022.907529.
Evaluation of the safety of a plant-based infant formula containing almonds and buckwheat in a neonatal piglet model Reprint Icon - (Peer Reviewed Journal)
Rosa, F., Yelvington, B., Terry, N., Tripp, P., Pittman III, H.E., Fay, B.L., Ross, T.J., Sikes, J.D., Flowers, J.B., Yoseph, F.B., Yeruva, V. 2022. Evaluation of the safety of a plant-based infant formula containing almonds and buckwheat in a neonatal piglet model. Nutrients. https://doi.org/10.3390/nu14071499.
Bacterial and fungal adaptations in cecum and distal colon of piglets fed dairy-based milk formula in comparison to human milk Reprint Icon - (Peer Reviewed Journal)
Elolimy, A., Rosa, F., Tripp, P., Bowlin, A.K., Randolph, C., Robeson, M., Yeruva, V. 2022. Bacterial and fungal adaptations in cecum and distal colon of piglets fed dairy-based milk formula in comparison to human milk. Frontiers in Microbiology. https://doi.org/10.3389/fmicb.2022.801854.
Milk from women diagnosed with COVID-19 does not contain SARS-CoV-2 RNA but has persistent levels of SARS-CoV-2-specific IgA antibodies Reprint Icon - (Peer Reviewed Journal)
Pace, R.M., Williams, J.E., Järvinen, K.M., Meehan, C.L., Martin, M.A., Ley, S.H., Barbosa-Leiker, C., Andres, A., Yeruva, V., Belfort, M.B., Caffe, B., Navarrete, A.D., Lackey, K.A., Pace, C., Gogel, A.C., Fehrenkamp, B.D., Klein, M., Young, B., Rosen-Carole, C., Diaz, N., Gaw, S.L., Flaherman, V., Mcguire, M.A., Mcguire, M.K., Seppo, A. 2021. Milk from women diagnosed with COVID-19 does not contain SARS-CoV-2 RNA but has persistent levels of SARS-CoV-2-specific IgA antibodies. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2021.801797.
Milk formula diet alters bacterial and host protein profile in comparison to human milk diet in neonatal piglet model Reprint Icon - (Peer Reviewed Journal)
Rosa, F., Zybailov, B., Glazko, G.V., Rahmatallah, Y., Byrum, S., Mackintosh, S.G., Bowlin, A.K., Yeruva, V. 2021. Milk formula diet alters bacterial and host protein profile in comparison to human milk diet in neonatal piglet model. Nutrients. 13(11):3718. https://doi.org/10.3390/nu13113718.
Progression of diabetes is associated with changes in the ileal transcriptome and ileal-colon morphology in the UC Davis Type 2 diabetes mellitus rat Reprint Icon - (Peer Reviewed Journal)
Piccolo, B.D., Graham, J.L., Kang, P., Randolph, C.E., Shankar, K., Yeruva, V., Fox, R., Robeson, M.S., Moody, B., LeRoith, T., Stanhope, K.L., Adams, S.H., Havel, P.J. 2021. Progression of diabetes is associated with changes in the ileal transcriptome and ileal-colon morphology in the UC Davis Type 2 diabetes mellitus rat. Physiological Reports. 9(22):e15102. https://doi.org/10.14814/phy2.15102.