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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Ruminant Diseases and Immunology Research » People & Locations » Fred Tatum
Fred M Tatum
Ruminant Diseases and Immunology Research
Research Microbiologist

Phone: (515) 337-7639
Fax: (515) 337-7458

(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)

Projects
Host-pathogen Interactions and Control Strategies for Bacterial Respiratory Pathogens in Cattle
In-House Appropriated (D)
  Accession Number: 441196
Host-pathogen Interactions and Control Strategies for Bacterial Respiratory Pathogens in Cattle
Non-Assistance Cooperative Agreement (S)
  Accession Number: 442729
Evaluate ARS Vaccine Candidates Against Mycoplasma Mycoides Subspecies Mycoides
Non-Assistance Cooperative Agreement (S)
  Accession Number: 444859

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Complete hybrid genome assembly of mannheimia haemolytica serotype A2 strain D95 isolated from ovine lung Reprint Icon - (Peer Reviewed Journal)
Goldkamp, A.K., Menghwar, H., Dassanayake, R.P., Tatum, F.M., Briggs, R.E., Casas, E. 2024. Complete hybrid genome assembly of mannheimia haemolytica serotype A2 strain D95 isolated from ovine lung. Microbiology Resource Announcements. Article e0055224. https://doi.org/10.1128/mra.00552-24.
Characterization of Histophilus somni sialic acid uptake mutant (¿nanP-¿nanU) using a mouse septicemia and mortality model Reprint Icon - (Peer Reviewed Journal)
Menghwar, H., Tatum, F.M., Briggs, R.E., Kanipe, C.R., Casas, E., Kaptur, J.A., Kaplan, B.S., Inzana, T.J., Azadi, P., Dassanayake, R.P. 2024. Characterization of Histophilus somni sialic acid uptake mutant (¿nanP-¿nanU) using a mouse septicemia and mortality model. Microbial Pathogenesis. 194. Article 106839. https://doi.org/10.1016/j.micpath.2024.106839.
Complete genome sequence of a Histophilus somni Strain 91 i from a beef calf with pneumonia Reprint Icon - (Peer Reviewed Journal)
Menghwar, H., Ma, H., Briggs, R.E., Tatum, F.M., Casas, E., Dassanayake, R.P. 2024. Complete genome sequence of a Histophilus somni Strain 91 i from a beef calf with pneumonia. Microbiology Resource Announcements. Article e00570-24. https://doi.org/10.1128/mra.00570-24.
An injectable subunit vaccine containing Elongation Factor Tu and Heat Shock Protein 70 protects North American bison from Mycoplasma bovis infection Reprint Icon - (Peer Reviewed Journal)
Kaplan, B.S., Dassanayake, R.P., Briggs, R.E., Kanipe, C.R., Boggiatto, P.M., Crawford, L., Olsen, S.C., Menghwar, H., Casas, E., Tatum, F.M. 2024. An injectable subunit vaccine containing Elongation Factor Tu and Heat Shock Protein 70 protects North American bison from Mycoplasma bovis infection. Frontiers in Veterinary Science. 11. Article 1408861. https://doi.org/10.3389/fvets.2024.1408861.
Transcriptomic profiles of Mannheimia haemolytica planktonic and biofilm associated cells Reprint Icon - (Peer Reviewed Journal)
Ma, H., Alt, D.P., Falkenberg, S.M., Briggs, R.E., Tatum, F.M., Clawson, M.L., Casas, E., Dassanayake, R.P. 2024. Transcriptomic profiles of Mannheimia haemolytica planktonic and biofilm associated cells. PLOS ONE. 19(2). Article e0297692. https://doi.org/10.1371/journal.pone.0297692.
Enhanced phagocytosis and complement-mediated killing of Mannheimia haemolytica serotype 1 following in-frame CMP-sialic acid synthetase (neuA) gene deletion Reprint Icon - (Peer Reviewed Journal)
Menghwar, H., Tatum, F.M., Briggs, R.E., Casas, E., Kaplan, B.S., Azadi, P., Dassanayake, R.P. 2023. Enhanced phagocytosis and complement-mediated killing of Mannheimia haemolytica serotype 1 following in-frame CMP-sialic acid synthetase (neuA) gene deletion. Microbiology Spectrum. Article e0294423. https://doi.org/10.1128/spectrum.02944-23.
Differential identification of Mannheimia haemolytica genotypes 1 and 2 using colorimetric loop-mediated isothermal amplification Reprint Icon - (Peer Reviewed Journal)
Dassanayake, R.P., Clawson, M.L., Tatum, F.M., Briggs, R.E., Kaplan, B.S., Casas, E. 2023. Differential identification of Mannheimia haemolytica genotypes 1 and 2 using colorimetric loop-mediated isothermal amplification. BMC Research Notes. 16. Article 4. https://doi.org/10.1186/s13104-023-06272-8.
Comparative study of antibacterial activity and stability of D-enantiomeric and L-enantiomeric bovine NK-lysin peptide NK2A Reprint Icon - (Peer Reviewed Journal)
Dassanayake, R.P., Porter, T.J., Samorodnitsky, D., Falkenberg, S.M., Nicholson, E.M., Tatum, F.M., Briggs, R.E., Palmer, M.V., Casas, E. 2022. Comparative study of antibacterial activity and stability of D-enantiomeric and L-enantiomeric bovine NK-lysin peptide NK2A. Biochemical and Biophysical Research Communications. 595:76-81. https://doi.org/10.1016/j.bbrc.2022.01.071.
Protection against Mycoplasma bovis infection in calves following intranasal vaccination with modified-live Mannheimia haemolytica expressing Mycoplasma antigens Reprint Icon - (Peer Reviewed Journal)
Briggs, R.E., Billing, S.R., Boatwright Jr, W.D., Chriswell, B.O., Casas, E., Dassanayake, R.P., Palmer, M.V., Register, K.B., Tatum, F.M. 2021. Protection against Mycoplasma bovis infection in calves following intranasal vaccination with modified-live Mannheimia haemolytica expressing Mycoplasma antigens. Microbial Pathogenesis. 161. Article 105159. https://doi.org/10.1016/j.micpath.2021.105159.
A pseudomolecule assembly of the Rocky Mountain elk genome Reprint Icon - (Peer Reviewed Journal)
Masonbrink, R.E., Alt, D.P., Bayles, D.O., Boggiatto, P.M., Edwards, H., Tatum, F.M., Williams, J.E., Wilson-Welder, J.H., Wood, M., Zimin, A., Severin, A., Olsen, S.C. 2021. A pseudomolecule assembly of the Rocky Mountain elk genome. PLoS ONE. 16(4). https://doi.org/10.1371/journal.pone.0249899.
Synthetic bovine NK-lysin-derived peptide (bNK2A) does not require intra-chain disulfide bonds for bactericidal activity Reprint Icon - (Peer Reviewed Journal)
Dassanayake, R.P., Falkenberg, S.M., Nicholson, E.M., Briggs, R.E., Tatum, F.M., Sharma, V.K., Reinhardt, T.A. 2019. Synthetic bovine NK-lysin-derived peptide (bNK2A) does not require intra-chain disulfide bonds for bactericidal activity. PLoS One. 14(6). https://doi.org/10.1371/journal.pone.0218507.
Capsular Polysaccharide Interferes With Biofilm Formation by Pasteurella Multocida Serogroup A Reprint Icon - (Peer Reviewed Journal)
Petruzzi, B., Briggs, R.E., Tatum, F.M., Swords, W.E., De Castro, C., Molinaro, A., Inzana, T.J. 2017. Capsular polysaccharide interferes with biofilm formation by Pasteurella multocida Serogroup A. mBio. 8(6):e01843-17. https://doi.org/10.1128/mBio.01843-17.
Antimicrobial activity of bovine NK-lysin-derived peptides on bovine respiratory pathogen Histophilus somni Reprint Icon - (Peer Reviewed Journal)
Dassanayake, R.P., Falkenberg, S.M., Briggs, R.E., Tatum, F.M., Sacco, R.E. 2017. Antimicrobial activity of bovine NK-lysin-derived peptides on bovine respiratory pathogen Histophilus somni. PLoS One. 12(8):1-14. doi. 10.1371/journal.pone.0183610.
Antimicrobial activity of bovine NK-lysin-derived peptides on bovine respiratory pathogen Histophilus somni - (Abstract Only)
Swine Brucellosis: Current Perspectives - (Peer Reviewed Journal)
Genome sequences of serotype A6 Mannheimia haemolytica isolates D174 and D38 recovered from bovine pneumonia Reprint Icon - (Peer Reviewed Journal)
Hauglund, M.J., Tatum, F.M., Bayles, D.O., Maheswaran, S.K., Briggs, R.E. 2015. Genome sequences of serotype A6 Mannheimia haemolytica isolates D174 and D38 recovered from bovine pneumonia. Genome Announcements. 3(2):e00093-15. DOI: 10.1128/genomeA.00086-15.
Genome sequences of Mannheimia haemolytica serotype A2 isolates D171 and D35, recovered from bovine pneumonia Reprint Icon - (Peer Reviewed Journal)
Hauglund, M.J., Tatum, F.M., Bayles, D.O., Maheswaran, S.K., Briggs, R.E. 2015. Genome sequences of Mannheimia haemolytica serotype A2 isolates D171 and D35, recovered from bovine pneumonia. Genome Announcements. 3(2):1e00093-15. DOI 10.1128/genomeA.00093-15.
Human neutrophil leukocyte elastase activity is inhibited by Phenol Red - (Abstract Only)
Genome sequences of Mannheimia haemolytica serotype A1 strains D153 and D193 from bovine pneumonia - (Peer Reviewed Journal)
Hauglund, M.J., Tatum, F.M., Bayles, D.O., Maheswaran, S.K., Briggs, R.E. 2013. Genome sequences of Mannheimia haemolytica serotype A1 strains D153 and D193 from bovine pneumonia. Genome Announcements. 1(5). DOI: 10.1128/genomeA.00848-13.
Bivalent vaccination against pneumonic pasteurellosis in domestic sheep and goats with modified-live in-frame lktA deletion mutants of Mannheimia haemolytica - (Peer Reviewed Journal)
Briggs, R.E., Hauglund, M.J., Maheswarn, S., Tatum, F.M. 2013. Bivalent vaccination against pneumonic pasteurellosis in domestic sheep and goats with modified-live in-frame lktA deletion mutants of Mannheimia haemolytica. Microbial Pathogenesis. 64:43-47. DOI 10.1016/j.micpath.2013.08.004.
Genome sequences of Mannheimia haemolytica serotype A1 strains D153 and D193 from bovine pneumonia Reprint Icon - (Peer Reviewed Journal)
Hauglund, M.J., Tatum, F.M., Bayles, D.O., Maheswaran, S.K., Briggs, R.E. 2013. Genome sequences of Mannheimia haemolytica serotype A1 strains D153 and D193 from bovine pneumonia. Genome Announcements. 1(5):e00848-13. DOI: 10.1128/genomeA.00848-13.
Comparative genome analysis of an avirulent and two virulent strains of avian Pasteurella multocida reveals candidate genes involved in fitness and pathogenicity Reprint Icon - (Peer Reviewed Journal)
Johnson, T.J., Abrahante, J.E., Hunter, S.S., Hauglund, M.J., Tatum, F.M., Maheswaran, S.K., Briggs, R.E. 2013. Comparative genome analysis of an avirulent and two virulent strains of avian Pasteurella multocida reveals candidate genes involved in fitness and pathogenicity. Biomed Central (BMC) Genomics. 13:106.
Draft genome sequences of two virulent serotypes of avian Pasteurella multocida - (Peer Reviewed Journal)
Abrahante, J.E., Johnson, T.J., Hunter, S.S., Maheswaran, S.K., Hauglund, M.J., Bayles, D.O., Tatum, F.M., Briggs, R.E. 2013. Draft genome sequences of two virulent serotypes of avian Pasteurella multocida. Genome Announcements. 1(1):e00058. DOI:10.1128/genomeA.00058-12.
Cross protection against fowl cholera disease with the use of recombinant Pasteurella multocida FHAB2 peptides vaccine - (Peer Reviewed Journal)
Tatum, F.M., Tabatabai, L.B., Briggs, R.E. 2012. Cross protection against fowl cholera disease with the use of recombinant Pasteurella multocida FHAB2 peptides vaccine. Avian Diseases. 56(3):589-591.
Mucosal and parenteral vaccination against pneumonic pasteurellosis in cattle with a modified-live in-frame lktA deletion mutant of Mannheimia haemolytica - (Peer Reviewed Journal)
Briggs, R.E., Tabatabai, L.B., Tatum, F.M. 2012. Mucosal and parenteral vaccination against pneumonic pasteurellosis in cattle with a modified-live in-frame lktA deletion mutant of Mannheimia haemolytica. Microbial Pathogenesis. 52(5):302-309.
Ornithobacterium rhinotracheale North American Field Isolates Express a Hemolysin-Like Protein - (Peer Reviewed Journal)
Tabatabai, L.B., Zimmerli, M.K., Zehr, E.S., Briggs, R.E., Tatum, F.M. 2010. Ornithobacterium rhinotracheale North American field isolates express a hemolysin-like protein. Avian Diseases. 54(3):994-1001.
Bovine Brucellosis - (Peer Reviewed Journal)
Olsen, S.C., Tatum, F.M. 2010. Bovine Brucellosis. Veterinary Clinics of North America. 26(1):15-27.
Sialic Acid Uptake Is Necessary for Virulence of Pasteurella multocida in turkeys - (Peer Reviewed Journal)
Tatum, F.M., Tabatabai, L.B., Briggs, R.E. 2009. Sialic Acid uptake is necessary for virulence of Pasteurella multocida in turkeys. Microbial Pathogenesis. 46(6):337-344.
Protection against Fowl Cholera Conferred by Recombinant Pasteurella Multocida Filamentous Hemagglutinin Peptides - (Peer Reviewed Journal)
Tatum, F.M., Tabatabai, L.B., Briggs, R.E. 2009. Protection Against Fowl Cholera Conferred by Vaccination with Recombinant Pasteurella multocida Filamentous Hemagglutinin Peptides. Avian Diseases. 53(2):169-174.
Characterization of a Hemolysin-like Activity of Ornithobacterium Rhinotracheale Field Strains - (Abstract Only)
Tabatabai, L.B., Zimmerli, M.K., Zehr, E.S., Tatum, F.M., Briggs, R.E. 2008. Characterization of a Hemolysin-like Activity of Ornithobacterium Rhinotracheale Field Strains [abstract]. Conference Research Workers Disease Meeting, December 7-9, 2008, Chicago, Illinois. p. 132.
Protection Against Fowl Cholera Conferred by Recombinant Pasteurella Multocida Filamentous Hemmagglutinin - (Abstract Only)
Tatum, F.M., Tabatabai, L.B., Briggs, R.E. 2008. Protection Against Fowl Cholera Conferred by Recombinant Pasteurella Multocida Filamentous Hemmagglutinin [abstract]. Conference for Research Workers in Animal Disease. Abstract No. 111. p. 123.
Viruses as Predisposing Factors to Bacterial Pneumonia - (Abstract Only)
Lehmkuhl, H.D., Briggs, R.E., Sacco, R.E., Tatum, F.M. 2007. Viruses as Predisposing Factors to Bacterial Pneumonia [abstract]. Respiratory Disease in Mountain Sheep: Knowledge Gaps and Future Research. p. 154.
The CHAPS-soluble outer membrane proteome of Pasteurella multocida - (Abstract Only)
Tabatabai, L.B., Zimmerli, M.K., Zehr, E.S., Briggs, R.E., Tatum, F.M. 2006. The CHAPS-soluble outer membrane proteome of Pasteurella multocida [abstract]. Conference Research Workers Disease Meeting. Paper No. 15.
AN UPDATE OF TURKEY RESEARCH AT THE NATIONAL ANIMAL DISEASE CENTER - (Other)
Briggs, R.E., Register, K.B., Tabatabai, L.B., Tatum, F.M., Scupham, A.J., Wesley, I.V. 2006. An update of turkey research at the National Animal Disease Center. Poultry Science Day, May 25, 2006, Ames, Iowa. 2006 CDROM.
THE PASTEURELLA MULTOCIDA OUTER MEMBRANE PROTEOME - (Abstract Only)
Tabatabai, L.B., Zimmerli, M.K., Briggs, R.E., Tatum, F.M. 2006. The pasteurella multocida outer membrane proteome [abstract]. Protein Society Symposium. Paper No. 293-588.
Respiratory Diseases of Poultry - (Other)
Tabatabai, L.B., Briggs, R.E., Tatum, F.M., Register, K.B. 2006. Respiratory Diseases of Poultry. Poultry Science Day, May 25, 2006, Ames, Iowa. 2006 CDROM.
LKTA DELETION MUTANT OF PASTEURELLA HAEMOLYTICA - (Abstract Only)
Briggs, R.E., Tatum, F.M. 2005. Lkta deletion mutant of pasteurella haemolytica. Patent Application. U.S. Patent 6,936,262, issued August 30, 2005.
GENERATION AND MOLECULAR CHARACTERIZATION OF NEW TEMPERATURE-SENSITIVE PLASMIDS FOR THE PASTEURELLACEAE - (Peer Reviewed Journal)
Briggs, R.E., Tatum, F.M. 2005. Generation and Molecular Characterization of New Temperature-Sensitive Plasmids for the Pasteurellaceae. Applied and Environmental Microbiology. 71(11):7187-7195.
CONSTRUCTION OF IN-FRAME AROA DELETION MUTANTS OF MANNHEIMIA HAEMOLYTICA, PASTEURELLA MULTOCIDA, AND HAEMOPHILUS SOMNUS USING A NEW TEMPERATURE-SENSITIVE PLASMID - (Peer Reviewed Journal)
Tatum, F.M., Briggs, R.E. 2005. Construction of in-frame aroa deletion mutants of Mannheimia haemolytica, Pasteurella multocida, and Haemophilus somnus using a new temperature-sensitive plasmid. Applied and Environmental Microbiology. 71(11):7196-7202.
Generation and Molecular Characterization of New Temperature-Sensitive Plasmids Intended for Genetic Engineering of Pasteurellaceae - (Peer Reviewed Journal)
Briggs, R.E., Tatum, F.M. 2005. Generation and Molecular Characterization of New Temperature-Sensitive Plasmids Intended for Genetic Engineering of Pasteurellaceae. Applied and Environmental Microbiology. 71(11):7187-7195.
CONSTRUCTION AND VIRULENCE OF A PASTEURELLA MULTOCIDA FHAB2 MUTANT IN TURKEYS - (Peer Reviewed Journal)
Tatum, F.M., Yersin, A.G., Briggs, R.E. 2005. Construction and virulence of a Pasteurella multocida fhaB2 mutant in turkeys. Microbial Pathogenesis. 39:9-17.
CONSTRUCTION OF IN-FRAME, NON-POLAR, LKTA MUTANTS OF MANNHEIMIA HAEMOLYTICA USING A NEW TEMPERATURE CONDITIONAL PLASMID AND EFFICACY AS MODIFIED-LIVE MUCOSAL VACCINE CANDIDATES (ORAL PRESENT., INTL. PASTEURELLACEAE CONF.) - (Abstract Only)
BRIGGS, R.E., TATUM, F.M. CONSTRUCTION OF IN-FRAME, NON-POLAR, LKTA MUTANTS OF MANNHEIMIA HAEMOLYTICA USING A NEW TEMPERATURE CONDITIONAL PLASMID AND EFFICACY AS MODIFIED-LIVE MUCOSAL VACCINE CANDIDATES. INTERNATIONAL PASTEURELLACEAE SOCIETY CONFERENCE. 2002. ABSTRACT p. 35, #34.
TEMPERATURE SENSITIVE PLASMIDS OF P. HAEMOLYTICA - (Abstract Only)
TATUM, F.M., BRIGGS, R.E. TEMPERATURE SENSITIVE PLASMIDS OF P. HAEMOLYTICA. 2003. U.S. PATENT 6,573,093.
LKTA DELETION MUTANT OF P. HAEMOLYTICA - (Abstract Only)
TATUM, F.M., BRIGGS, R.E. LKTA DELETION MUTANT OF P. HAEMOLYTICA. 2002. U.S. PATENT 6,495,145.
CONSTRUCTION OF AN ISOGENIC LEUKOTOXIN DELETION MUTANT OF PASTEURELLA HAEMOLYTICA SEROTYPE 1: CHARACTERIZATION AND VIRULENCE (FINAL TITLE) - (Peer Reviewed Journal)
PASTEURELLA HAEMOLYTICA LEUKOTOXIN: VIRULENCE FACTOR AND IMMUNOGEN (HAEMOPHILUS, ACTINOBACILLUS, AND PASTEURELLA INTERNATIONAL CONFERENCE, ACAPULCO, MEXICO, OCTOBER 13-17, 1996) - (Abstract Only)
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