Research Project: Improved Analytical Technologies for Detection of Foodborne Toxins and Their Metabolites

Location: Mycotoxin Prevention and Applied Microbiology Research

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Predictive quantitative structure-activity relationship modeling of the antifungal and antibiotic properties of triazolothiadiazine compounds - (Peer Reviewed Journal)
Appell, M.D., Compton, D.L., Evans, K.O. 2020. Predictive quantitative structure-activity relationship modeling of the antifungal and antibiotic properties of triazolothiadiazine compounds. Methods and Protocols. 4(1). Article 2. https://doi.org/10.3390/mps4010002.

Developments in mycotoxin analysis: an update for 2019-2020 - (Review Article)
Tittlemeir, S.A., Brunkhorst, J., Cramer, B., DeRosa, M.C., Lattanzio, V.M.T., Malone, R., Maragos, C., Stranska, M., Sumarah, M.W. 2021. Developments in mycotoxin analysis: an update for 2019-2020. World Mycotoxin Journal. 14(1):3-26. https://doi.org/10.3920/WMJ2020.2664.

Quantum chemical and quantitative structure activity relationship (QSAR) assessment of the antifungal properties of phenolic compounds - (Abstract Only)
Appell, M., Tu, Y.-S., Compton, D.L., Evans, K.O., Wang, L. 2020. Quantum chemical and quantitative structure activity relationship (QSAR) assessment of the antifungal properties of phenolic compounds. American Chemistry Society Abstracts. [abstract].

Changing the landscape: an introduction to the AGFD technical program at the 258th ACS national meeting in San Diego - (Proceedings)
Appell, M., Biswas, A., Chang, S, Chen, W., Cheng, H.N., Daily, J., F. Xuetong Fan, Granvogl, M., Guo, M., Ito, Y., Jin, T., Kobori, M., Leland, J.V., Liu, L.S., Luo, Y., MacMahon, S., Mahattanatawee, K., Nam, S., Osorio, C., Park, B., Ren, D., Sang, S., Shahidi, F., Tunick, M., Udenigwe, C.C. Wang, Q., Yokoyama, W.H., Yu, L., Zhang, Y., Zhu Y. 2020. Changing the landscape: an introduction to the Agricultural and Food Chemistry Technical Program at the 258th American Chemical Society National Meeting in San Diego. Journal of Agricultural and Food Chemistry 68(46):12769-12772. DOI: 10.1021/acs.jafc.0c02809

Development and characterisation of a monoclonal antibody to detect the mycotoxin roquefortine C - (Peer Reviewed Journal)
Maragos, C.M. 2020. Development and characterisation of a monoclonal antibody to detect the mycotoxin roquefortine C. Food Additives & Contaminants. 37(10):1777-1790. https://doi.org/10.1080/19440049.2020.1781937.

Quantitative structure-activity relationship study for prediction of antifungal properties of phenolic compounds - (Peer Reviewed Journal)
Appell, M.D., Tu, Y., Compton, D.L., Evans, K.O., Wang, L.C. 2020. Quantitative structure-activity relationship study for prediction of antifungal properties of phenolic compounds. Structural Chemistry. 31:1621-1630. https://doi.org/10.1007/s11224-020-01549-1.

Ochratoxin A analysis in wine and grape juice using LC-fluorescence detection with nanosponge solid phase extraction clean-up - (Abstract Only)
Appell, M., Evans, K.O., Jackson, M.A., Compton, D.L. 2019. Ochratoxin A analysis in wine and grape juice using LC-fluorescence detection with nanosponge solid phase extraction clean-up [abstract].

Analytical challenges associated with detection of emerging, masked, and modified mycotoxins - (Abstract Only)
Maragos, C.M. 2020. Analytical challenges associated with detection of emerging, masked, and modified mycotoxins. [abstract].

Developments in mycotoxin analysis: an update for 2018-19 - (Review Article)
Tittlemier, S.A., Cramer, B., Dall'Asta, C., Iha, M.H., Lattanzio, V.M.T., Maragos, C., Solfrizzo, M., Stranska, M., Stroka, J., Sumarah, M. 2020. Developments in mycotoxin analysis: an update for 2018-19. World Mycotoxin Journal. 13(1):3-24. https://doi.org/10.3920/WMJ2019.2535.

Intestinal hydrolysis and microbial biotransformation of diacetoxyscirpenol-a-glucoside, HT-2-ß-glucoside and N-(1-deoxyd-d-fructos-1-yl) fumonisin B1 by human gut microbiota in vitro - (Peer Reviewed Journal)
Daud, N., Currie, V., Duncan, G., Busman, M., Gratz, S.W. 2019. Intestinal hydrolysis and microbial biotransformation of diacetoxyscirpenol-a-glucoside, HT-2-ß-glucoside and N-(1-deoxyd-d-fructos-1-yl) fumonisin B1 by human gut microbiota in vitro. International Journal of Food Sciences and Nutrition. 71(5):540-548. https://doi.org/10.1080/09637486.2019.1698015.

Mycotoxins that chelate: a tool for probing toxin/metal interactions - (Abstract Only)
Maragos, C.M., Hossain, M.Z. 2019. Mycotoxins that chelate: a tool for probing toxin/metal interactions [abstract].

Development and characterization of monoclonal antibodies for the mycotoxin citreoviridin - (Peer Reviewed Journal)
Maragos, C.M., Uchiyama, Y., Kobayashi, N., Kominato, F., Sugita-Konishi, Y. 2019. Development and characterization of monoclonal antibodies for the mycotoxin citreoviridin. Toxins. 11(11):630. https://doi.org/10.3390/toxins11110630.

Development of antibodies for the mycotoxin citreoviridin - (Abstract Only)
Maragos, C.M., Kobayashi, N., Uchiyama, Y., Sugita-Konishi, Y. 2019. Development of antibodies for the mycotoxin citreoviridin [abstract].

Fluorescence polarization immunoassays for the determination of trichothecenes and their modified forms in wheat - (Abstract Only)
Lippolis, V., Porricelli, A.C.R., Mancini, E., Lattanzio, V.M.T., Ciasca, B., De Girolamo, A., De Saeger, S., Maragos, C.M., McCormick, S.P., Li, P., Logrieco, A.F., Pascale, M. 2019. Fluorescence polarization immunoassays for the determination of trichothecenes and their modified forms in wheat [abstract].

Commercial immunoassays for detecting aflatoxins - (Book / Chapter)
Maragos, C.M. 2020. Commercial immunoassays for detecting aflatoxins. Chapter 4, In: Kintzios, S., Mavrikou, S. editors. Aflatoxins: Biochemistry, Toxicology, Public Health, Policies and Modern Methods of Analysis., Hauppauge, NY: Nova Science Publishers, Inc. p. 91-115.

Biomimetic agro-based materials for food safety - (Abstract Only)
Appell, M., Jackson, M.A., Evans, K.O., Compton, D.L., Bosma, W.B. 2019. Biomimetic agro-based materials for food safety [abstract].

Fluorescence polarization immunoassay for the determination of T-2 and HT-2 toxins and their glucosides in wheat - (Peer Reviewed Journal)
Lippolis, V., Porricelli, A.C.R., Mancini, E., Ciasca, B., Lattanzio, V.M.T., De Girolamo, A., Maragos, C.M., McCormick, S., Li, P., Logrieco, A.F., Pascale, M. 2019. Fluorescence polarization immunoassay for the determination of T-2 and HT-2 toxins and their glucosides in wheat. Toxins. 11(7):380. https://doi.org/10.3390/toxins11070380.

Detection of fungal toxins - (Abstract Only)

Immunoassay utilizing imaging surface plasmon resonance for the detection of cyclopiazonic acid (CPA) in maize and cheese - (Peer Reviewed Journal)
Hossain, Z., Busman, M., Maragos, C.M. 2019. Immunoassay utilizing imaging surface plasmon resonance for the detection of cyclopiazonic acid (CPA) in maize and cheese. Analytical and Bioanalytical Chemistry. 411:3543–3552. https://doi.org/10.1007/s00216-019-01835-w.

Comprehensive theoretical investigation of alternariol and alternariol monomethyl ether - (Abstract Only)
Tu, Y.-S., Tseng, Y.J., Appell, M. 2019. Comprehensive theoretical investigation of alternariol and alternariol monomethyl ether [abstract].

Application of ab initio molecular dynamic simulation in 4D fingerprints - (Abstract Only)
Tu, Y.-S., Tseng, Y.J., Appell, M. 2019. Application of ab initio molecular dynamic simulation in 4D fingerprints [abstract].

Coordination of mycotoxins with lanthanides in luminescent complexes - (Peer Reviewed Journal)
Hossain, M.Z., Maragos, C.M. 2019. Coordination of mycotoxins with lanthanides in luminescent complexes. Mycotoxin Research. 35(3):279-292. https://doi.org/10.1007/s12550-019-00356-w.

Quantum chemical investigation of the detection properties of alternariol and alternariol monomethyl ether - (Peer Reviewed Journal)
Tu, Y.-S., Tseng, Y.J., Appell, M. 2019. Quantum chemical investigation of the detection properties of alternariol and alternariol monomethyl ether. Structural Chemistry. https://doi.org/10.1007/s11224-019-01302-3.

Developments in mycotoxin analysis: an update for 2017-2018 - (Review Article)
Tittlemier, S.A., Cramer, B., Dall'Asta, C., Iha, M.H., Lattanzio, V.M.T., Malone, R.J., Maragos, C., Solfrizzo, M., Stranska-Zachariasova, M., Stroka, J. 2019. Developments in mycotoxin analysis: an update for 2017-2018. World Mycotoxin Journal. 12(1):3-29. https://doi.org/10.3920/WMJ2018.2398.

Determination of ochratoxin A in grape juice and wine using nanosponge solid phase extraction clean-up and liquid chromatography with fluorescence detection - (Peer Reviewed Journal)
Appell, M., Evans, K.O., Jackson, M.A., Compton, D.L. 2019. Determination of ochratoxin A in grape juice and wine using nanosponge solid phase extraction clean-up and liquid chromatography with fluorescence detection. Journal of Liquid Chromatography and Related Technologies. 41:949-954. https://doi.org/10.1080/10826076.2018.1544148.

Cross-reactivity of commercial and non-commercial deoxynivalenol-antibodies to emerging trichothecenes and common deoxynivalenol-derivatives - (Peer Reviewed Journal)
Nguyen, N.T., Varga, E., Maragos, C., Baumgartner, S., Adam, G., Berthiller, F. 2018. Cross-reactivity of commercial and non-commercial deoxynivalenol-antibodies to emerging trichothecenes and common deoxynivalenol-derivatives. World Mycotoxin Journal. 12:45-53. https://doi.org/10.3920/WMJ2018.2363.

Detection of modified mycotoxins in corn - (Abstract Only)
Maragos, C.M. 2018. Detection of modified mycotoxins in corn [abstract].

Quantum molecular dynamics and cheminformatics study of mycotoxin detection and toxicity to improve food safety - (Abstract Only)
Tu, Y.-S., Tseng, Y.J., Appell, M. 2018. Quantum molecular dynamics and cheminformatics study of mycotoxin detection and toxicity to improve food safety [Abstract].

Theoretical investigation of cyromazine tautomerism using density functional theory and Moller–Plesset perturbation theory methods - (Peer Reviewed Journal)
Tu, Y.-S., Tseng, Y.J., Appell, M. 2018. Theoretical investigation of cyromazine tautomerism using density functional theory and Moller–Plesset perturbation theory methods. Molecular Simulation. 44(16):1344-1352. https://doi.org/10.1080/08927022.2018.1506117.

Complexation of the mycotoxin cyclopiazonic acid with lanthanides yields luminescent products - (Peer Reviewed Journal)
Maragos, C.M. 2018. Complexation of the mycotoxin cyclopiazonic acid with lanthanides yields luminescent products. Toxins. 10(7):285. https://doi.org/10.3390/toxins10070285.

Chemist of the year award - (Abstract Only)
Appell, M.D. 2018. Chemist of the year award [abstract].

Theoretical investigation of cyromazine tautomerism using density functional theory and Møller–Plesset perturbation theory methods - (Abstract Only)
Tu, Y.-S., Tseng, Y.J., Appell, M.D. 2018. Theoretical investigation of cyromazine tautomerism using density functional theory and Møller–Plesset perturbation theory methods [abstract].

Computational studies on the excited state properties of citrinin and application in fluorescence analysis - (Abstract Only)

Development of antibodies for N-(1-deoxy-D-fructos-1-yl) fumonisin B1 and cross-reaction with modified fumonisins - (Peer Reviewed Journal)
Maragos, C.M., Sieve, K.K., Busman, M. 2019. Development of antibodies for N-(1-deoxy-D-fructos-1-yl) fumonisin B1 and cross-reaction with modified fumonisins. World Mycotoxin Journal. 11:493-502. https://doi.org/10.3920/WMJ2018.2308.

An imaging surface plasmon resonance biosensor assay for the detection of T-2 toxin and masked T-2 toxin-3-glucoside in wheat - (Peer Reviewed Journal)
Hossain, M.Z, McCormick, S.P., Maragos, C.M., 2018. An imaging surface plasmon resonance biosensor assay for the detection of T-2 toxin and masked T-2 toxin-3-glucoside in wheat. Toxins. 10(3)119.

Amino acids and proteins - (Book / Chapter)
Appell, M., Hurst, W.J., Finley, J.W., deMan, J.M. 2018. Amino acids and proteins. In: deMan, J.M., Finley, J.W., Hurst, W.J., Lee, C.Y., editors. Principles of Food Chemistry. 4th edition. New York, NY: Springer. p. 117-164.

Spectroscopic and time-dependent density functional investigation of the role of structure on the acid-base effects of citrinin detection - (Peer Reviewed Journal)
Appell, M., Evans, K.O., Compton, D.L., Wang, L.C., Bosma, W.B. 2018. Spectroscopic and time-dependent density functional investigation of the role of structure on the acid-base effects of citrinin detection. Structural Chemistry. 29(3):715-723. https://doi.org/10.1007/s11224-017-1065-1.

Multiplexed imaging surface plasmon resonance (iSPR) biosensor assay for the detection of Fusarium toxins in wheat - (Abstract Only)

Developments in mycotoxin analysis: an update for 2016-2017 - (Review Article)
Berthiller, F., Cramer, B., Iha, M.H., Krska, R., Lattanzio, V.M.T., MacDonald, S., Malone, R.J., Maragos, C., Solfrizzo, M., Stranska-Zachariasova, M., Stroka, J., Tittlemier, S.A. 2018. Developments in mycotoxin analysis: an update for 2016-2017. World Mycotoxin Journal. 11(1):5-32.

Gold nanoparticle-enhanced multiplexed imaging surface plasmon resonance (iSPR) detection of Fusarium mycotoxins in wheat - (Peer Reviewed Journal)
Hossain, M., Maragos, C.M. 2017. Gold nanoparticle-enhanced multiplexed imaging surface plasmon resonance (iSPR) detection of Fusarium mycotoxins in wheat. Biosensors and Bioelectronics. 101:246-253.

Chemical approaches to solve mycotoxin problems and improve food safety - (Abstract Only)

Quantitation of mycotoxins using direct analysis in real time mass spectrometry (DART-MS) - (Review Article)
Busman, M. 2018. Quantitation of mycotoxins using direct analysis in real time mass spectrometry (DART-MS). Journal of AOAC International. 101(3):643-646. https://doi.org/10.5740/jaoacint.17-0338.

Spectroscopic and time-dependent density functional theory investigation of the photophysical properties of zearalenone and its analogs - (Abstract Only)

Imaging surface plasmon resonance detection for T-2 toxin in wheat - (Abstract Only)

Analysis of the photophysical properties of zearalenone using density functional theory - (Peer Reviewed Journal)
Appell, M., Wang, L.C., Bosma, W.B. 2017. Analysis of the photophysical properties of zearalenone using density functional theory. Luminescence. 188:551-557.

Detection of cyclopiazonic acid (CPA) in maize by immunoassay - (Peer Reviewed Journal)
Maragos, C.M., Sieve, K.K., Bobell, J. 2017. Detection of cyclopiazonic acid (CPA) in maize by immunoassay. Mycotoxin Research. 33(2):157-165.

Selection and application of strand displacement probes for a fumonisin B1 aptamer - (Peer Reviewed Journal)
Wang, H., Wang, J., Hong, H., Yin, H., Maragos, C.M., Zhang, L., Liu, J. 2017. Selection and application of strand displacement probes for a fumonisin B1 aptamer. Quality and Safety of Agro-Products. 1:44-48.

Detection of mycotoxins using imaging surface plasmon resonance (iSPR) - (Abstract Only)

Developments in mycotoxin analysis: an update for 2015-2016 - (Review Article)
Berthiller, F., Brera, C., Iha, M.H., Krska, R., Lattanzio, V.M.T., MacDonald, S., Malone, R.J., Maragos, C., Solfrizzo, M., Stranska-Zachariasov, M., Stroka, J., Tittlemier, S.A. 2017. Developments in mycotoxin analysis: an update for 2015-2016. World Mycotoxin Journal. 10(1):5-29.

Metabolomic evaluation of conditions favoring mycotoxin production in isolates of Fusarium fungi - (Abstract Only)
Busman, M. 2016. Metabolomic evaluation of conditions favoring mycotoxin production in isolates of Fusarium fungi [abstract]. American Society for Mass Spectrometry.

Materials science approaches to solve problems with emerging mycotoxins in corn - (Abstract Only)
Appell, M. 2016. Materials science approaches to solve problems with emerging mycotoxins in corn [abstract].