Location: Characterization and Interventions for Foodborne Pathogens
Title: Genome sequences of 34 Shiga toxin-producing E. coli isolated from swine and other sourcesAuthor
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BARANZONI, GIAN MARCO - University Of Birmingham |
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Fratamico, Pina |
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KIM, GWANGHEE - Collaborator |
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Reichenberger, Erin |
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FUNK, JULIE - University Of Michigan |
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MANNING, SHANNON - University Of Michigan |
Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal Publication Acceptance Date: 10/12/2017 Publication Date: 11/2/2017 Citation: Baranzoni, G., Fratamico, P.M., Kim, G., Reichenberger, E.R., Funk, J., Manning, S. 2017. Genome sequences of 34 Shiga toxin-producing E. coli isolated from swine and other sources. Genome Announcements. https://doi.org/10.1128/genomeA.01214-17. Interpretive Summary: Shiga toxin-producing Escherichia coli (STEC) are major food-borne pathogens and are carried in the intestines of various animals. Even though cattle are considered the major reservoir for STEC, swine also carry the pathogens and play a role in maintaining these bacteria in the environment. Some types of swine STEC are able to cause illnesses, such as diarrhea and edema disease pigs, and some types can also cause human illness. Swine STEC strains, however, have not been well characterized. Therefore, the genome sequence (genetic material of a bacterium) of 34 STEC strains was determined to better characterize the STEC population in pigs to gain a better understanding of their virulence (ability to cause illness) potential. In particular, 29 STEC strains were isolated from healthy swine, three similar strains were obtained from beef trim and used for comparison, and two strains were collected from ill pigs that had diarrhea and edema disease, respectively. Comparative analyses of the genomes of the STEC is shedding light on the virulence of swine STEC and characteristics of strains that cause illness in swine and in humans. Technical Abstract: Shiga toxin-producing Escherichia coli (STEC) are food-borne pathogens that can be carried by various animals. The swine STEC population is partially composed of host-specific strains that are often not well characterized. In this work, the genome sequences of a number of swine STEC strains are presented. |