Location: Foodborne Toxin Detection and Prevention Research
Title: Ex vivo and in vitro methods for detection of bioactive staphylococcal enterotoxinsAuthor
Submitted to: Book Chapter
Publication Type: Book / Chapter Publication Acceptance Date: 11/27/2021 Publication Date: 3/15/2022 Citation: Rasooly, R., Do, P.M., Hernlem, B.J. 2022. Ex vivo and in vitro methods for detection of bioactive staphylococcal enterotoxins. In: Ossandon, M.R., Baker, H., Rasooly, A., editors. Biomedical Engineering Technologies. Volume 1. New York, NY: Humana Press. p. 237-255. https://doi.org/10.1007/978-1-0716-1803-5_13. DOI: https://doi.org/10.1007/978-1-0716-1803-5_13 Interpretive Summary: Staphylococcal enterotoxins (SEs) belong to a family of some 23 different toxins secreted by staphylococcal and streptococcal bacteria but share common parts of their protein structure and are responsible for cause vomiting and food poisoning affecting about a quarter million people every year in the United States (US). This chapter describes methods for detecting these toxins in their active form without using live animals. Technical Abstract: Staphylococcal enterotoxins (SEs) are members of a family of some 23 different staphylococcal and streptococcal exotoxins which share structural motifs, have emetic activity and are causative agents of bacterial food poisoning that affects about a quarter million people every year in the United States (US). This chapter describes ex vivo and in vitro methods for detection of bioactive staphylococcal enterotoxins. |