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ARS Home » Pacific West Area » Albany, California » Western Regional Research Center » Foodborne Toxin Detection and Prevention Research » Research » Publications at this Location » Publication #375837

Research Project: Advance the Development of Technologies for Detecting and Determining the Stability and Bioavailability of Toxins that Impact Food Safety and Food Defense

Location: Foodborne Toxin Detection and Prevention Research

Title: Ex vivo and in vitro methods for detection of bioactive staphylococcal enterotoxins

Author
item Rasooly, Reuven
item Do, Paula
item Hernlem, Bradley - Brad

Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: 11/27/2021
Publication Date: 3/15/2022
Citation: Rasooly, R., Do, P.M., Hernlem, B.J. 2022. Ex vivo and in vitro methods for detection of bioactive staphylococcal enterotoxins. In: Ossandon, M.R., Baker, H., Rasooly, A., editors. Biomedical Engineering Technologies. Volume 1. New York, NY: Humana Press. p. 237-255. https://doi.org/10.1007/978-1-0716-1803-5_13.
DOI: https://doi.org/10.1007/978-1-0716-1803-5_13

Interpretive Summary: Staphylococcal enterotoxins (SEs) belong to a family of some 23 different toxins secreted by staphylococcal and streptococcal bacteria but share common parts of their protein structure and are responsible for cause vomiting and food poisoning affecting about a quarter million people every year in the United States (US). This chapter describes methods for detecting these toxins in their active form without using live animals.

Technical Abstract: Staphylococcal enterotoxins (SEs) are members of a family of some 23 different staphylococcal and streptococcal exotoxins which share structural motifs, have emetic activity and are causative agents of bacterial food poisoning that affects about a quarter million people every year in the United States (US). This chapter describes ex vivo and in vitro methods for detection of bioactive staphylococcal enterotoxins.