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ARS Home » Northeast Area » Wyndmoor, Pennsylvania » Eastern Regional Research Center » Characterization and Interventions for Foodborne Pathogens » Research » Publications at this Location » Publication #391715
Research Project: Detection, Quantification and Characterization Technologies for Foodborne Pathogens

Location: Characterization and Interventions for Foodborne Pathogens

Title: Complete genome sequences of multidrug-resistant Campylobacter coli strains YH501, YH503, and YH504 from retail chicken

Author
item He, Yiping
item Reed, Sue
item Yan, Xianghe
item ZHANG, DANDAN - Molecular Epidemiology, Inc
item Strobaugh Jr, Terence
item Capobianco, Joseph
item Gehring, Andrew

Submitted to: Microbiology Resource Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 6/22/2022
Publication Date: 7/16/2022
Citation: He, Y., Reed, S.A., Yan, X., Zhang, D., Strobaugh Jr, T.P., Capobianco Jr, J.A., Gehring, A.G. 2022. Complete genome sequences of multidrug-resistant Campylobacter coli strains YH501, YH503, and YH504 from retail chicken. Microbiology Resource Announcements. Available online: https://www.researchgate.net/journal/Microbiology-Resource-Announcements-2576-098X. https://doi.org/10.1128%2Fmra.00237-22.
DOI: https://doi.org/10.1128%2Fmra.00237-22

Interpretive Summary: Campylobacter bacterium is a major cause of foodborne illnesses worldwide. In this study, three strains of Campylobacter coli were isolated from retail chicken. Three whole genomes were sequenced, de novo assembled, and the resulting genes were “annotated” (i.e., their functionality was identified). Analyses of the complete genomes revealed numerous virulence and antibiotic resistance genes, suggesting a high potential for these poultry isolates to cause disease in humans. The sequence data and completely assembled genomes of the C. coli isolates were provided to NCBI GenBank to disseminate these findings to researchers across various scientific disciplines. The complete genome sequences and annotations advance crucial research on the subject of genetic diversity and evolution of this important foodborne pathogen.

Technical Abstract: Campylobacter coli is an important foodborne pathogen, which can cause inflammation of the intestine and diarrhea in humans. The complete genomes including mega-plasmids of C. coli strains YH501, YH503 and YH504 from retail chicken were sequenced, de novo assembled, and characterized. These results contribute to our understanding of the genetic properties of Campylobacter spp. Whole genome analysis revealed a number of virulence and antibiotic resistant genes, suggesting a high potential for these poultry originated isolates to cause human disease.