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ARS Home » Midwest Area » Columbia, Missouri » Plant Genetics Research » People & Locations » Paula Chen
Paula Chen
Plant Genetics Research
Research Molecular Biologist

Phone: (573) 882-5209
Fax:

(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)

Projects
Validate Causative Mutations in Agriculturally-Important Vertebrates
In-House Appropriated (D)
  Accession Number: 443341
Genetic Regulation of Ovarian Follicular Progression in Japanese Quail
Non-Assistance Cooperative Agreement (S)
  Accession Number: 443593
Development of Strategies for Coordinated Expression of Pathway Genes
Non-Assistance Cooperative Agreement (S)
  Accession Number: 444218
Establishment and Characterization of Liver Organoids from Layer Chickens
Non-Assistance Cooperative Agreement (S)
  Accession Number: 444344
Validate Causative Mutations in Poultry
Non-Assistance Cooperative Agreement (S)
  Accession Number: 446231

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Mitochondrial dysfunction is a hallmark of woody breast myopathy in broiler chickens - (Peer Reviewed Journal)
Research Note: Up-regulation of Melanophilin (MLPH) gene during avian adipogenesis and decreased fat pad weights with adipocyte hypotrophy in MLPH knockout quail - (Peer Reviewed Journal)
Gentamicin has no significant adverse affect on porcine embryo development in vitro Reprint Icon - (Peer Reviewed Journal)
Noland, R.S., Redel, B.K., Lamartina, M.G., Chen, P.R., Prather, R.S. 2024. Gentamicin has no significant adverse affect on porcine embryo development in vitro. Molecular Reproduction and Development. 91(12). https://doi.org/10.1002/mrd.70008.
Research note: Increased lipid accumulation within broiler preadipocytes during differentiation in vitro at atmospheric oxygen tension Reprint Icon - (Peer Reviewed Journal)
Cruvinel, J.M., Greene, E.S., Read, R.W., Lee, K., Dridi, S., Chen, P.R. 2024. Research note: Increased lipid accumulation within broiler preadipocytes during differentiation in vitro at atmospheric oxygen tension. Poultry Science. 104(1). https://doi.org/10.1016/j.psj.2024.104531.
Fetal bone engraftment reconstitutes the immune system in pigs with severe combined immunodeficiency Reprint Icon - (Peer Reviewed Journal)
Monarch, K., Yoon, J., Uh, K., Reese, E., Canaveral Restrepo, D., De Carvalho Madrid, D., Touchard, L., Spate, L.D., Samuel, M.S., Driver, J.P., Lim, J., Schlink, S., Whitworth, K.M., Wells, K.D., Prather, R.S., Chen, P.R., Lee, K. 2024. Fetal bone engraftment reconstitutes the immune system in pigs with severe combined immunodeficiency. Lab Animal. 53:276-286. https://doi.org/10.1038/s41684-024-01439-7.
Accelerating genomic improvement in pigs by using reproductive biotechnologies - (Book / Chapter)
Impaired skeletal development by disruption of presenilin-1 in pigs and generation of novel pig models for Alzheimer’s disease Reprint Icon - (Peer Reviewed Journal)
Uh, K., Monarch, K., Reese, E.D., Rodriguez, K., Yoon, J.D., Spate, L.D., Samuel, M.S., Koh, S., Chen, P.R., Jarome, T., Allen, T., Prather, R.S., Lee, K. 2024. Impaired skeletal development by disruption of presenilin-1 in pigs and generation of novel pig models for Alzheimer’s disease. Journal of Alzheimer's Disease. 101(2):445-461. https://doi.org/10.3233/JAD-231297.
Novel off-targeting events identified after genome wide analysis of CRISPR-Cas edited pigs Reprint Icon - (Peer Reviewed Journal)
Redel, B.K., Yoon, J., Reese, E., An, H., Uh, K., Chen, P.R., Prather, R.S., Lee, K. 2024. Novel off-targeting events identified after genome wide analysis of CRISPR-Cas edited pigs. The CRISPR Journal. 7(3): 141 - 149. https://doi.org/10.1089/crispr.2024.0012.
Porcine-specific expression of the three functional CYP19 paralogs in early conceptus, placenta, and gonads Reprint Icon - (Peer Reviewed Journal)
Lucas, C.G., Sullivan, R.M., Pfeiffer, C.A., Chen, P.R., Kim, J., Sponchiado, M.S., Conley, A.J., Prather, R.S., Wells, K.D., Geisert, R.D. 2023. Porcine-specific expression of the three functional CYP19 paralogs in early conceptus, placenta, and gonads. Reproduction. 166(4):263-269. https://doi.org/10.1530/REP-23-0189.
Inactivation of growth differentiation factor 9 blocks folliculogenesis in pigs Reprint Icon - (Peer Reviewed Journal)
Chen, P.R., Uh, K., Monarch, K., Spate, L., Reese, E., Prather, R., Lee, K. 2023. Inactivation of growth differentiation factor 9 blocks folliculogenesis in pigs. Biology of Reproduction. 108(4):611-618. https://doi.org/10.1093/biolre/ioad005.