Research Project: Intervention Strategies to Control Endemic and New and Emerging Viral Diseases of Swine

Location: Virus and Prion Research

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Senecavirus A in the environment of sow slaughter plants - (Proceedings)
Devries, A.C., Hoffman, K., Faaberg, K.S., Humphrey, N., Korslund, J., Lager, K.M. 2022. Senecavirus A in the environment of sow slaughter plants. American Association of Swine Veterinarians Annual Meeting. 22 June 2022. https://doi.org/10.3389/fvets.2022.923878.

Multiple site SUMOylation of FMDV 3C protease and its negative role in viral replication - (Peer Reviewed Journal)
Wu, X., Hu, Y., Sui, C., Pan, L., Li, F., Miller, L.C., Lee, C., Cong, X., Li, J., Du, Y., Qi, J. 2022. Multiple site SUMOylation of FMDV 3C protease and its negative role in viral replication. Journal of Virology. 96(17). Article e061222. https://doi.org/10.1128/jvi.00612-22.

Transcriptomic analysis of liver indicates novel vaccine to porcine reproductive and respiratory virus promotes homeostasis in T-Cell and inflammatory immune responses compared to commercial vaccine in pigs - (Peer Reviewed Journal)
Fleming, D.S., Miller, L.C., Li, J., Lager, K.M., Van Geelen, A., Sang, Y. 2022. Transcriptomic analysis of liver indicates novel vaccine to porcine reproductive and respiratory virus promotes homeostasis in T-Cell and inflammatory immune responses compared to commercial vaccine in pigs. Frontiers in Veterinary Science. 9. Article 791034. https://doi.org/10.3389/fvets.2022.791034.

The United States Swine Pathogen Database: Integrating veterinary diagnostic laboratory sequence data to monitor emerging pathogens of swine - (Peer Reviewed Journal)
Anderson, T.K., Inderski, B., Diel, D.G., Hause, B.M., Porter, E., Clement, T., Nelson, E.A., Bai, J., Lager, K.M., Faaberg, K.S., Christopher-Hennings, J., Gauger, P.C., Zhang, J., Harmon, K.M., Main, R. 2021. The United States Swine Pathogen Database: Integrating veterinary diagnostic laboratory sequence data to monitor emerging pathogens of swine. Database: The Journal of Biological Databases and Curation. 2021. Article baab078. https://doi.org/10.1093/database/baab078.

Host response in the porcine lymph node to infection by PRRSV 2, Influenza B and their coinfection - (Abstract Only)
Sarlo Davila, K.M., Fleming, D.S., Ma, W., Sang, Y., Miller, L.C. 2021. Host response in the porcine lymph node to infection by PRRSV 2, Influenza B and their coinfection. Meeting Abstract. https://doi.org/10.3920/978-90-8686-940-4.

Host response in the porcine mediastinal lymph node to infection by PRRSV 2, Influenza B and their coinfection - (Abstract Only)
Sarlo Davila, K.M., Fleming, D.S., Ma, W., Sang, Y., Miller, L.C. 2021. Host response in the porcine mediastinal lymph node to infection by PRRSV 2, Influenza B and their coinfection. Conference Research Workers Disease Meeting. CRWAD 2021 Proceedings-Page 43.

How transcriptomics can unravel disease pathology - (Abstract Only)
Sarlo Davila, K.M., Miller, L.C. 2021. How transcriptomics can unravel disease pathology. Meeting Abstract. Visions III Conference, Ames,Iowa.

Immunometabolic dysregulation at the intersection of obesity and COVID-19 - (Review Article)
Khwatenge, C.N., Pate, M., Miller, L.C., Sang, Y. 2021. Immunometabolic dysregulation at the intersection of obesity and COVID-19. Frontiers in Immunology. 12. Article 732913. https://doi.org/10.3389/fimmu.2021.732913.

Senecavirus A: Frequently asked questions - (Peer Reviewed Journal)
Devries, A.C., Lager, K.M. 2022. Senecavirus A: Frequently asked questions. Swine Health and Production. 30(3):149-159. https://doi.org/10.54846/jshap/1270.

Harness organoid models for virological studies in animals: A cross-species perspective - (Review Article)
Sang, Y., Miller, L.C., Nelli, R.K., Giménez-Lirola, L.G. 2021. Harness organoid models for virological studies in animals: A cross-species perspective. Frontiers in Microbiology. 12. Article 725074. https://doi.org/10.3389/fmicb.2021.725074.

Intravenous, intratracheal, and intranasal inoculation of swine with SARS-CoV-2 - (Peer Reviewed Journal)
Buckley, A.C., Falkenberg, S.M., Martins, M., Laverack, M., Palmer, M.V., Lager, K.M., Diego, D. 2021. Intravenous, intratracheal, and intranasal inoculation of swine with SARS-CoV-2. Viruses. 13(8). https://doi.org/10.3390/v13081506.

Detection of pseudorabies virus antibody in swine serum oral fluid specimens using a recombinant gE glycoprotein dual matrix indirect ELISA - (Peer Reviewed Journal)
Cheng, T., Magtoto, R., Henao-Diaz, A., Poonsuk, K., Devries, A.C., Van Geelen, A., Lager, K.M., Zimmerman, J., Gimenez-Lirola, L. 2021. Detection of pseudorabies virus antibody in swine serum oral fluid specimens using a recombinant gE glycoprotein dual matrix indirect ELISA. Journal of Veterinary Diagnostic Investigation. 33(6). p. 1106-1114. https://doi.org/10.1177/10406387211040755.

Family Arteriviridae - (Book / Chapter)

Tripal, a community update after 10 years of supporting open source, standards-based genetic, genomic and breeding databases - (Peer Reviewed Journal)
Staton, M., Cannon, E.K., Sanderson, L., Wegrzyn, J., Buehler, S., Ficklin, S., Grau, E., Guignon, V., Gunoskey, J., Jung, S., Main, D., Poelchau, M.F., Ramnath, R., Cobo, I., Richter, P., West, J., Anderson, T.K., Inderski, B., Faaberg, K.S., Lager, K.M. 2021. Tripal, a community update after 10 years of supporting open source, standards-based genetic, genomic and breeding databases. Briefings in Bioinformatics. 22(6). https://doi.org/10.1093/bib/bbab238.

Inhibition of antiviral innate immunity by Foot-and-Mouth Disease Virus Lpro through interaction with N-terminal domain of swine RNase L - (Peer Reviewed Journal)
Sui, C., Jiang, D., Wu, X., Liu, S., Li, F., Pan, L., Cong, X., Li, J., Yoo, D., Rock, D.L., Miller, L.C., Lee, C., Du, Y., Qi, J. 2021. Inhibition of antiviral innate immunity by Foot-and-Mouth Disease Virus Lpro through interaction with N-terminal domain of swine RNase L. Journal of Virology. 95(15). https://doi.org/10.1128/JVI.00361-21.

The United States Swine Pathogen Database: Integrating veterinary diagnostic laboratory sequence data to monitor emerging pathogens of swine - (Pre-print Publication)
Anderson, T.K., Inderski, B., Diel, D.G., Hause, B.M., Porter, E., Clement, T., Nelson, E.A., Bai, J., Lager, K.M., Faaberg, K.S., Christopher-Hennings, J., Gauger, P.C., Zhang, J., Harmon, K.M., Main, R. 2021. The United States Swine Pathogen Database: Integrating veterinary diagnostic laboratory sequence data to monitor emerging pathogens of swine. bioRxiv. https://doi.org/10.1101/2021.04.16.439882.

Pseudorabies (Aujeszky's disease) virus DNA detection in swine nasal swab and oral fluid specimens using a gB-based real-time quantitative PCR - (Peer Reviewed Journal)
Cheng, T., Henao-Diaz, A., Poonsuk, K., Buckley, A.C., Van Geelen, A., Lager, K.M., Harmon, K., Gauger, P., Wang, C., Ambagala, A., Zimmerman, J., Gimenez-Lirola, L. 2021. Pseudorabies (Aujeszky's disease) virus DNA detection in swine nasal swab and oral fluid specimens using a gB-based real-time quantitative PCR. Preventive Veterinary Medicine. 189. Article 105308. https://doi.org/10.1016/j.prevetmed.2021.105308.

Distribution and persistence of atypical porcine pestivirus in experimentally inoculated pigs - (Peer Reviewed Journal)
Buckley, A.C., Falkenberg, S.M., Palmer, M.V., Arruda, P.H., Magstadt, D.R., Schwartz, K.J., Gatto, I., Neill, J.D., Arruda, B.L. 2021. Distribution and persistence of atypical porcine pestivirus in experimentally inoculated pigs. Journal of Veterinary Diagnostic Investigation. 33(5):952-955. https://doi.org/10.1177/10406387211022683.

Epigenetic evolution of ACE2 and IL-6 genes as non-canonical interferon-stimulated genes correlate to COVID-19 susceptibility in vertebrates - (Abstract Only)
Sang, E.R., Tian, Y., Gong, Y., Miller, L.C., Sang, Y. 2021. Epigenetic evolution of ACE2 and IL-6 genes as non-canonical interferon-stimulated genes correlate to COVID-19 susceptibility in vertebrates [abstract]. American Society for Virology Meeting. Virtual.

Angiotensin-converting enzyme 2 (ACE2) receptor on the surface of mammalian cells and evolution of ACE2-related immunogenetic diversity to restrict SARS-CoV2 infections - (Abstract Only)
Miller, L.C. 2021. Angiotensin-converting enzyme 2 (ACE2) receptor on the surface of mammalian cells and evolution of ACE2-related immunogenetic diversity to restrict SARS-CoV2 infections [Abstract]. USDA-Western Regional Research Center (WRRC)- Pacific West Area (PWA).Virtual.

Epigenetic evolution of ACE2 and IL-6 genes as non-canonical interferon-stimulated genes correlate to COVID-19 susceptibility in vertebrates - (Peer Reviewed Journal)
Sang, E.R., Tian, Y., Gong, Y., Miller, L.C., Sang, Y. 2021. Epigenetic evolution of ACE2 and IL-6 genes as non-canonical interferon-stimulated genes correlate to COVID-19 susceptibility in vertebrates. Genes. 12(2). Article 12020154. https://doi.org/10.3390/genes12020154.

Integrate structural analysis, isoform diversity, and interferon-inductive propensity of ACE2 to predict SARS-CoV-2 susceptibility in vertebrates - (Abstract Only)
Miller, L.C. 2020. Integrate structural analysis, isoform diversity, and interferon-inductive propensity of ACE2 to predict SARS-CoV-2 susceptibility in vertebrates [abstract]. Baker Center for Bioinformatics and Biological Statistics.Virtual.

Integrate structural analysis, isoform diversity, and interferon-inductive propensity of ACE2 to predict SARS-CoV-2 susceptibility in vertebrates - (Abstract Only)
Miller, L.C. 2020. Integrate structural analysis, isoform diversity, and interferon-inductive propensity of ACE2 to predict SARS-CoV-2 susceptibility in vertebrates [abstract]. PROCINORTE Animal Health Task Force. Virtual.

Pathogenesis and control of Senecavirus A in swine - (Other)
Devries, A.C. 2021. Pathogenesis and control of Senecavirus A in swine. Iowa State University, Ames, Thesis. https://doi.org/10.31274/etd-20210114-20.

Comparison of historical and contemporary isolates of Senecavirus A - (Peer Reviewed Journal)
Buckley, A.C., Michael, D.D., Faaberg, K.S., Guo, B., Yoon, K., Lager, K.M. 2020. Comparison of historical and contemporary isolates of Senecavirus A. Veterinary Microbiology. 253. Article 108946. https://doi.org/10.1016/j.vetmic.2020.108946.

Integrate structural analysis, isoform diversity, and interferon-inductive propensity of ACE2 to refine SARS-CoV2 susceptibility prediction in vertebrates - (Abstract Only)
Sang, E.R., Tian, Y., Gong, Y., Miller, L.C., Sang, Y. 2020. Integrate structural analysis, isoform diversity, and interferon-inductive propensity of ACE2 to refine SARS-CoV2 susceptibility prediction in vertebrates [abstract]. United States Animal Health Association Proceedings. P. none assigned.

Development and utilization of an infectious clone for porcine deltacoronavirus strain USA/IL/2014/026 - (Peer Reviewed Journal)
Deng, X., Buckley, A.C., Pillatzki, A., Lager, K.M., Baker, S.C., Faaberg, K.S. 2020. Development and utilization of an infectious clone for porcine deltacoronavirus strain USA/IL/2014/026. Virology. 553:35-45. https://doi.org/10.1016/j.virol.2020.11.002.

Impact of porcine arterivirus, influenza B, and their coinfection on antiviral response in the porcine lung - (Peer Reviewed Journal)
Fleming, D.S., Miller, L.C., Tian, Y., Li, Y., Ma, W., Sang, Y. 2020. Impact of porcine arterivirus, influenza B, and their coinfection on antiviral response in the porcine lung. Pathogens. 9(11). Article 9110934. https://doi.org/10.3390/pathogens9110934.

Inactivating multiple coronavirus interferon antagonists attenuates pathogenesis of porcine epidemic diarrhea virus - (Abstract Only)
Buckley, A.C., Deng, X., Pillatzki, A., Lager, K.M., Faaberg, K.S., Baker, S. 2021. Inactivating multiple coronavirus interferon antagonists attenuates pathogenesis of porcine epidemic diarrhea virus [abstract]. American Association of Swine Veterinarians Annual Meeting. Poster No. 37.

Experimental intravenous, intratracheal, and intranasal inoculation of swine with SARS-CoV-2 - (Abstract Only)
Buckley, A.C., Falkenberg, S.M., Laverack, M., Martins, M., Palmer, M.V., Diel, D., Lager, K.M. 2020. Experimental intravenous, intratracheal, and intranasal inoculation of swine with SARS-CoV-2 [abstract]. American Association of Swine Veterinarians Annual Meeting. p. 35-37.

Persistent infection and protection against Senecavirus A in pigs previously infected with a homologous and a heterologous isolate - (Abstract Only)
Preis, G., Devries, A.C., Wiese, W., Vannucci, F. 2021. Persistent infection and protection against Senecavirus A in pigs previously infected with a homologous and a heterologous isolate. American Association of Swine Veterinarians Annual Meeting. Poster No. 54.

Detection of pseudorabies virus in oral fluid specimen using real-time PCR - (Abstract Only)
Cheng, T., Harmon, K., Gauger, P., Wang, C., Ambagala, A., Buckley, A.C., Van Geelen, A., Lager, K.M., Zimmerman, J., Gimenez-Lirola, L. 2020. Detection of pseudorabies virus in oral fluid specimen using real-time PCR [abstract]. American Association of Veterinary Laboratory Diagnosticians. p. not available.

Integrate structural analysis, Isoform diversity, and interferon-inductive propensity of ACE2 to refine SARS-CoV2 susceptibility prediction in vertebrates - (Peer Reviewed Journal)
Sang, E.R., Tian, Y., Gong, Y., Miller, L.C., Sang, Y. 2020. Integrate structural analysis, Isoform diversity, and interferon-inductive propensity of ACE2 to refine SARS-CoV2 susceptibility prediction in vertebrates. Heliyon. e04818. https://doi.org/10.1016/j.heliyon.2020.e04818.

Too much of a good thing: Antiviral response and tissue damage during respiratory infections in the porcine lung - (Abstract Only)

Integrate structural analysis, Isoform diversity, and interferon-inductive propensity of ACE2 to refine SARS-CoV2 susceptibility prediction in vertebrates - (Abstract Only)

Inactivating three interferon antagonists attenuates pathogenesis of an enteric coronavirus - (Peer Reviewed Journal)
Deng, X., Buckley, A.C., Pillatzki, A., Lager, K.M., Faaberg, K.S., Baker, S.C. 2020. Inactivating three interferon antagonists attenuates pathogenesis of an enteric coronavirus. Journal of Virology. 94(17). https://doi.org/10.1128/JVI.00565-20.

Validation of a PRRSV live-virus potentiated by replication-competent expression of porcine interferons - (Proceedings)

Comparative virulence and genomic analysis of streptococcus suis isolates - (Abstract Only)

Detection of pseudorabies virus antibody in swine oral fluid using a serum whole-virus indirect ELISA - (Peer Reviewed Journal)
Cheng, T., Buckley, A.C., Van Geelen, A., Lager, K.M., Henao-Diaz, A., Poonsuk, K., Pineyro, P., Baum, D., Ji, J., Wang, C., Main, R., Zimmerman, J., Gimenez-Lirola, L. 2020. Detection of pseudorabies virus antibody in swine oral fluid using a serum whole-virus indirect ELISA. Journal of Veterinary Diagnostic Investigation. https://doi.org/10.1177/1040638720924386.

Porcine messenger RNA and microRNA pathway analysis of PRRSV infection - (Proceedings)
Miller, L.C., Flemming, D.S. 2020. Porcine messenger RNA and microRNA pathway analysis of PRRSV infection. In: Proceedings of Journal of Immunology. May 8-12, 2020, Honolulu, Hawaii. 204(1 Supplement)92.14.

Comparison of the transcriptome response within the swine tracheobronchial lymphnode following infection with PRRSV, PCV-2 or IAV-S - (Peer Reviewed Journal)
Miller, L.C., Fleming, D.S., Lager, K.M. 2020. Comparison of the transcriptome response within the swine tracheobronchial lymphnode following infection with PRRSV, PCV-2 or IAV-S. Pathogens. 9(2):99. https://doi.org/10.3390/pathogens9020099.

The United States swine pathogen database: integrating diagnostic sequence data of emerging pathogens of swine - (Abstract Only)
Inderski, B., Anderson, T.K., Faaberg, K.S. 2020. The United States swine pathogen database: integrating diagnostic sequence data of emerging pathogens of swine [abstract]. The International Plant and Animal Genome XXVIII Conference. Abstract No. W1097.

(w)HOL(e)ISTIC gene ontology and pathway analysis of data using open source web tools - (Peer Reviewed Journal)
Fleming, D.S., Miller, L.C. 2020. (w)HOL(e)ISTIC gene ontology and pathway analysis of data using open source web tools. Genomics Data. https://doi.org/10.21203/rs.2.20371/v1.

The development of a diagnostic assay using oral fluids for the detection of Senecavirus A - (Abstract Only)
Zelenka, A.M., Buckley, A.C., Huang, Y.S., Hettenbach, S.M., Stack, J., Higgs, S., Vanlandingham, D.L. 2019. The development of a diagnostic assay using oral fluids for the detection of Senecavirus A [abstract]. Great Plains Infectious Disease meeting. Paper No. 1.

Transcriptomic analysis among sub-clinically ill cattle following bovine respiratory disease vaccine protocol and challenge with bovine viral diarrhea virus - (Peer Reviewed Journal)
Fleming, D.S., Herring, A.D., Miller, L.C., Gill, C.A. 2019. Transcriptomic analysis among sub-clinically ill cattle following bovine respiratory disease vaccine protocol and challenge with bovine viral diarrhea virus. BioMed Central (BMC) Immunology. https://doi.org/10.21203/rs.2.16902/v1.

Porcine anti-viral immunity: how important is it? - (Review Article)
Lager, K.M., Buckley, A.C. 2019. Porcine anti-viral immunity: how important is it? Frontiers in Immunology. 10:2258. https://doi.org/10.3389/fimmu.2019.02258.

Persistent atypical porcine pestivirus (APPV) infection in gilts - (Abstract Only)
Buckley, A.C., Arruda, B., Falkenberg, S.M., Miller, L.C., Lager, K.M. 2019. Persistent atypical porcine pestivirus (APPV) infection in gilts. Meeting Abstract. p. 35.

Efficacy of an inactivated Seneca Valley virus vaccine in pregnant sows - (Abstract Only)
Buckley, A.C., Lager, K.M. 2019. Efficacy of an inactivated Seneca Valley virus vaccine in pregnant sows. Meeting Abstract. p. 36.

Pseudorabies virus (PRV) antibody detection in swine serum and oral fluid specimens - (Abstract Only)
Cheng, T., Buckley, A.C., Van Geelen, A., Lager, K.M., Henao-Diaz, A., Poonsuk, K., Pineyro, P., Ji, J., Wang, C., Baum, D., Main, R., Zimmerman, J., Gimenez-Lirola, L. 2020. Pseudorabies virus (PRV) antibody detection in swine serum and oral fluid specimens. American Association of Swine Veterinarians Annual Meeting. Atlanta, Georgia. March 7-10, 2020, p. 37.

The status of PRRSV in North America and the influence of vaccines - (Abstract Only)

Characterization of homologous protective humoral immunity against Seneca Valley virus - (Abstract Only)
Kim, H., Buckley, A.C., Guo, B., Lager, K.M., Yoon, K. 2019. Characterization of homologous protective humoral immunity against Seneca Valley virus. Conference for Research Workers in Animal Diseases (CRWAD)2019 [abstract] p. 198.

Detection of pseudorabies virus (PRV) antibody in serum and oral fluid specimens from inoculated and/or vaccinated pigs using a whole virus indirect IgG ELISA - (Abstract Only)
Cheng, T., Buckley, A.C., Van Geelen, A., Lager, K.M., Henao-Diaz, A., Poonsuk, K., Pineyro, P., Wang, C., Baum, D., Main, R., Zimmerman, J., Gimenez-Lirola, L. 2019. Detection of pseudorabies virus (PRV) antibody in serum and oral fluid specimens from inoculated and/or vaccinated pigs using a whole virus indirect IgG ELISA. Meeting Abstract. Paper No. 45.

Integrative genomics and network biology in livestock and other domestic animals: differentially expressed miRNAs and tRNA genes affect host homeostasis during highly pathogenic porcine reproductive and respiratory syndrome - (Book / Chapter)
Fleming, D.S., Miller, L.C. 2020. Integrative genomics and network biology in livestock and other domestic animals: differentially expressed miRNAs and tRNA genes affect host homeostasis during highly pathogenic porcine reproductive and respiratory syndrome. Frontiers in Genetics. p. 150. https://doi.org/10.3389/978-2-88963-999-1.

Differentially expressed miRNAs and tRNA genes effect host homeostasis during highly pathogenic porcine reproductive and respiratory syndrome virus infections in young pigs - (Peer Reviewed Journal)
Fleming, D.S., Miller, L.C. 2019. Differentially expressed miRNAs and tRNA genes effect host homeostasis during highly pathogenic porcine reproductive and respiratory syndrome virus infections in young pigs. Frontiers in Genetics. 10:691. https://doi.org/10.3389/fgene.2019.00691.

e-PIG-enetics: Porcine miRNA and tRNA expression during highly pathogenic PRRSV infections - (Abstract Only)
Fleming, D.S., Miller, L.C. 2019. e-PIG-enetics: Porcine miRNA and tRNA expression during highly pathogenic PRRSV infections.[abstract]. ISAG 37th International Society for Animal Genetics Conference. p. 211.

E-PIG-enetic avenues: porcine mRNA and miRNA pathway analysis of highly pathogenic PRRSV infection - (Abstract Only)
Fleming, D.S., Miller, L.C. 2019. E-PIG-enetic avenues: porcine mRNA and miRNA pathway analysis of highly pathogenic PRRSV infection [abstract]. IVIS 2019 International Veterinary Immunology Symposium . p. 51.

Experimental Seneca Valley virus infection in market-weight gilts - (Peer Reviewed Journal)
Buckley, A., Kulshreshtha, V., van Geelen, A., Montiel, N., Guo, B., Yoon, K., Lager, K. 2019. Experimental Seneca Valley virus infection in market-weight gilts. Veterinary Microbiology. 231:7-10. https://doi.org/10.1016/j.vetmic.2019.02.019.

Experimental Seneca Valley virus infection in market-weight gilts - (Peer Reviewed Journal)
Buckley, A., Kulshreshtha, V., van Geelen, A., Montiel, N., Guo, B., Yoon, K.-Jin, Lager, K. 2019. Experimental Seneca Valley virus infection in market-weight gilts. Veterinary Microbiology. 231:7-10. https://doi.org/10.1016/j.vetmic.2019.02.019.

Dual regulation of nuclear/plasma distribution and modification of TRAIP by porcine reproductive and respiratory syndrome virus nonstructural protein 1alpha promotes viral proliferation - (Peer Reviewed Journal)
Shi, P., Su, Y., Li, R., Zhang, L., Chen, C., Zhang, L., Faaberg, K., Huang, J. 2019. Dual regulation of host TRAIP post-translation and nuclear/plasma distribution by porcine reproductive and respiratory syndrome virus non-structural protein 1alpha promotes viral proliferation. Frontiers in Immunology. 9:3023. https://doi.org/10.3389/fimmu.2018.03023.

Efficacy of an inactivated Seneca Valley virus vaccine in nursery-aged pigs - (Abstract Only)
Buckley, A., Patterson, A., Van Geelen, A., Lager, K.M. 2018. Efficacy of an inactivated Seneca Valley virus vaccine in nursery-aged pigs. Vaccine. 36(6):841-846. https://doi.org/10.1016/j.vaccine.2017.12.055.

Pieces of a dream: A study in mapping transfer RNA fragments (tRFs) within the porcine genome - (Abstract Only)
Fleming, D.S., Miller, L.C. 2018. Pieces of a dream: A study in mapping transfer RNA fragments (tRFs) within the porcine genome [abstract]. North American Porcine Reproductive and Respiratory Syndrome (NA-PRRS) Symposium. Abstract No. PRRS 27.

Dexamethasone treatment did not exacerbate experimental Seneca Valley virus infection in nursery-age pigs - (Peer Reviewed Journal)
Buckley, A., Montiel, N., Guo, B., Kulshreshtha, V., van Geelen, A., Hoang, H., Rademacher, C., Yoon, K.-J., Lager, K. 2018. Dexamethasone treatment did not exacerbate Seneca Valley virus infection in nursery-age pigs. BMC Veterinary Research. 14:352. https://doi.org/10.1186/s12917-018-1693-8.

Spatial and temporal patterns of swine IAV gene constellations in the USA from 2010 to 2018 - (Abstract Only)
Chang, J., Anderson, T.K., Vincent, A.L. 2018. Spatial and temporal patterns of swine IAV gene constellations in the USA from 2010 to 2018 [abstract]. Research Workers in Animal Diseases Conference Proceedings. p. none assigned.

Sequence comparison of historic and contemporary strains of Senecavirus A - (Abstract Only)
Buckley, A., Michael, D.D., Guo, B., Van Geelen, A., Yoon, K., Lager, K.M. 2018. Sequence comparison of historic and contemporary strains of Senecavirus A. Research Workers in Animal Diseases Conference Proceedings [abstract]. Paper No. 267.

The United States Swine Pathogen Database: integrating veterinary diagnostic laboratory sequence data to monitor emerging pathogens of swine - (Abstract Only)
Anderson, T.K., Inderski, B., Diel, D.G., Porter, E., Clement, T., Nelson, E.A., Bai, J., Christopher-Hennings, J., Lager, K.M., Faaberg, K.S. 2018. The United States Swine Pathogen Database: integrating veterinary diagnostic laboratory sequence data to monitor emerging pathogens of swine [abstract]. Research Workers in Animal Diseases Conference Proceedings. Abstract No. 199.

The United States Swine Pathogen Database: integrating veterinary diagnostic laboratory sequence data to monitor emerging pathogens of swine - (Abstract Only)
Anderson, T.K., Inderski, B., Diel, D.G., Porter, E., Clement, T., Nelson, E.A., Bai, J., Christopher-Hennings, J., Lager, K.M., Faaberg, K.S. 2018. The United States Swine Pathogen Database: integrating veterinary diagnostic laboratory sequence data to monitor emerging pathogens of swine [abstract]. North American Porcine Reproductive and Respiratory Syndrome (NA-PRRS) Symposium. Abstract No. 199.

e-PIG-enetics: porcine sncRNA response to highly pathogenic PRRSV - (Abstract Only)
Fleming, D.S., Miller, L.C. 2018. e-PIG-enetics: porcine sncRNA response to highly pathogenic PRRSV[abstract]. International Symposium of Animal Functional Genomics. abstract No. 14.

Identification of coding and non-coding RNA classes expressed in swine whole blood - (Peer Reviewed Journal)
Fleming, D.S., Anderson, S.J., Miller, L.C. 2018. Identification of coding and non-coding RNA classes expressed in swine whole blood. Journal of Visualized Experiments. (141):e58689. https://doi.org/10.3791/58689.

Expansion of the rank structure of the family Arteriviridae and renaming its taxa - (Peer Reviewed Journal)
Brinton, M.A., Gulyaeva, A., Udeni, U.B., Dunowska, M., Faaberg, K.S., Leung, F.C., Nauwynck, H.J., Snijder, E.J., Stadejek, T., Gorbalenya, A.E. 2019. Expansion of the rank structure of the family Arteriviridae and renaming its taxa. International Committee on Viral Taxonomy. (MSL#35). https://talk.ictvonline.org/files/master-species-lists/m/msl/9601.

Porcine mRNA and sncRNA expression intersections during viral infection - (Abstract Only)
Fleming, D.S., Miller, L.C. 2018. Porcine mRNA and sncRNA expression intersections during viral infection. International Animal Biotechnology Symposium, Cheongju, South Korea. Abstract. p. 3.

e-PIG-enetics: porcine miRNA and tRNA expression during highly pathogenic PRRSV infections - (Abstract Only)
Fleming, D.S., Miller, L.C. 2018. e-PIG-enetics: porcine miRNA and tRNA expression during highly pathogenic PRRSV infections. PAG-ASIA 2018. Abstract No. W060.

Comparison of the transcriptome response within the porcine tracheobronchial lymph node following viral infection - (Peer Reviewed Journal)
Miller, L., Fleming, D., Harhay, G., Kehrli, M., Lager, K. 2018. Comparison of the transcriptome response within the porcine tracheobronchial lymph node following viral infection. Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume Biology - Disease Resistance 2: 672.

Small non-coding RNA expression status in animals faced with highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) - (Peer Reviewed Journal)
Fleming, D.S., Miller, L. 2018. Small non-coding RNA expression status in animals faced with highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV). 2018. Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume Species - Porcine 2:595.

Live virus Immunization (LVI) with a recent 1-7-4 PRRSV isolate elicits broad protection against PRRSV challenge in finishing age swine - (Abstract Only)
Van Geelen, A.G., Buckley, A., Kulshreshtha, V., Brockmeier, S., Miller, L.C., Fleming, D., Loving, C.L., Faaberg, K.S., Lager, K.M. 2018. Live virus Immunization (LVI) with a recent 1-7-4 PRRSV isolate elicits broad protection against PRRSV challenge in finishing age swine. American Association of Swine Veterinarians 49th Annual Meeting, March 3-6, 2018, San Diego, California. Paper No. 69.

Transcriptome responses to respiratory virus infection of pigs within the tracheobronchial lymphnode following infection with PRRSV, PCV2 or IAV - (Abstract Only)
Miller, L.C., Fleming, D.S., Harhay, G.P., Kehrli, Jr., M.E., Lager, K.M. 2018. Transcriptome responses to respiratory virus infection of pigs within the tracheobronchial lymphnode following infection with PRRSV, PCV2 or IAV. The Journal of Immunology. Vol. 200(1 Supplement):59.14.

Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States - (Peer Reviewed Journal)
Rajao, D.S., Anderson, T.K., Kitikoon, P., Stratton, J., Lewis, N.S., Vincent, A.L. 2018. Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States. Virology. 518:45-54. https://doi.10.1016/j.virol.2018.02.006.

Identification of small non-coding RNA classes expressed in swine whole blood during HP-PRRSV infection - (Peer Reviewed Journal)
Fleming, D.S., Miller, L.C. 2018. Identification of small non-coding RNA classes expressed in swine whole blood during HP-PRRSV infection. Virology. 517:56-61. https://doi.org/10.1016/j.virol.2018.01.027.

Transcriptome responses to respiratory virus infection of pigs within the tracheobronchial lymphnode following infection with PRRSV, PCV2 or IAV - (Abstract Only)
Miller, L.C., Fleming, D.S., Harhay, G.P., Kehrli, Jr., M.E., Lager, K.M. 2018. Transcriptome responses to respiratory virus infection of pigs within the tracheobronchial lymphnode following infection with PRRSV, PCV2 or IAV. Plant & Animal Genome Conference XXVI, January 13-17, 2018, San Diego, California. Paper No. P1222.

Effect of miRNA and tRNA gene expression on the homeostatic status of pigs infected with highly pathogenic PRRSV - (Abstract Only)
Fleming, D.S., Miller, L.C. 2018. Effect of miRNA and tRNA gene expression on the homeostatic status of pigs infected with highly pathogenic PRRSV[abstract]. Plant and Animal Genome Conference. p. 453.

Comparative analysis of signature genes in PRRSV-infected porcine monocyte-derived cells to different stimuli - (Abstract Only)

Porcine reproductive and respiratory disease virus: evolution and recombination yields distinct ORF5 RFLP 1-7-4 viruses with individual pathogenicity - (Peer Reviewed Journal)
van Geelen, A.G.M., Anderson, T.K., Lager, K.M., Das, P.B., Otis, N.J., Montiel, N.A., Miller, L.C., Kulshreshtha, V., Buckley, A.C., Brockmeier, S.L., Zhang, J., Gauger, P.C., Harmon, K.M., Faaberg, K.S. 2018. Porcine reproductive and respiratory disease virus: evolution and recombination yields distinct ORF5 RFLP 1-7-4 viruses with individual pathogenicity. Virology. 513:168-179.

Comparative analysis of signature genes in PRRSV-infected porcine monocyte-derived cells to different stimuli - (Abstract Only)
Miller, L.C., Fleming, D., Li, X., Bayles, D., Blecha, F., Sang, Y. 2017. Comparative analysis of signature genes in PRRSV-infected porcine monocyte-derived cells to different stimuli. 98th Conference of Research Workers in Animal Diseases. Abstract No. 237, p. 131.

Comparison of the transcriptome response within the tracheobronchial lymphnode following infection with PRRSV, PCV2 or SIV - (Abstract Only)
Miller, L.C., Fleming, D., Harhay, G., Bayles, D., Kehrli, M., Lager, K. 2017. Comparison of the transcriptome response within the tracheobronchial lymphnode following infection with PRRSV, PCV2, or SIV. 98th Conference of Research Workers in Animal Diseases. Abstract No. 190, p. 107.

Effect of miRNA and tRNA gene expression on the homeostatic status of pigs infected with highly pathogenic PRRSV - (Abstract Only)
Fleming, D., Miller, L.C. 2017. Effect of miRNA and tRNA gene expression on the homeostatic status of pigs infected with highly pathogenic PRRSV. 98th Annual Conference of Research Workers in Animal Diseases, December 3-5, 2017, Chicago, Illinois. Abstract No. 189, p. 107.

Comparison of historic and contemporary strains of Senecavirus A - (Abstract Only)

Live virus immunization (LVI) with a recent 1-7-4 PRRSV isolate elicits broad protection against PRRSV challenge in finishing age swine - (Abstract Only)

Small non-coding RNAs (sncRNA) regulate gene silencing and modify homeostatic status in animals faced with porcine reproductive and respiratory syndrome virus (PRRSV) - (Abstract Only)

Transcriptomic analysis reveals the potential of highly pathogenic PRRS virus to modulate immune system activation related to host-pathogen and damage associated signaling in infected porcine monocytes - (Abstract Only)