Research Project: Multi-hurdle Approaches for Controlling Foodborne Pathogens in Poultry

Location: Poultry Production and Product Safety Research

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Electron beam-killed Staphylococcus vaccine reduced lameness in broiler chickens - (Peer Reviewed Journal)

Standardization of methodologies in poultry microbiome research: One year of progress - (Abstract Only)

Application of Electron beam (eBeam) technology to reduce foodborne pathogens and spoilage organisms in ground poultry meat - (Abstract Only)

Comparison of viabilities of Electron Beam-treated Staphylococcus and Salmonella – an insight for whole cell-inactivated vaccine preparation - (Abstract Only)

Immunogenic differences in primary immune response profiles to electron beam irradiated and formalin-inactivated Salmonella vaccines in pullets - (Abstract Only)

Vaccines in aquaculture development, production, and applications - (Book / Chapter)
Baskaralingam, V., Jesudhasan, P. 2024. Vaccines in Aquaculture Development, Production, and Applications. Book Chapter. 1st edition. Cambridge, MA: Eelsevier. p. 300.

Functional contribution of the intestinal microbiome in autism spectrum disorder, attention deficit hyperactivity disorder, and Rett syndrome: a systematic review of pediatric and adult studies - (Peer Reviewed Journal)
Caputi, V., Hill, L., Figueiredo, M., Popov, J., Hartung, E., Margolis, G.K., Baskaran, K., Joharapurker, P., Moshkovich, M., Pai, N. 2024. Functional contribution of the intestinal microbiome in autism spectrum disorder, attention deficit hyperactivity disorder, and Rett syndrome: a systematic review of pediatric and adult studies. Frontiers in Neuroscience. 18. Article 1341656. http://doi.org/10.3389/fnins.2024.1341656.

Cold stress initiates catecholaminergic and serotonergic responses in the chicken gut that are associated with functional shifts in the microbiome - (Peer Reviewed Journal)
Lyte, J.M., Eckenberger, J., Keane, J., Robinson, K., Bacon, T.F., Facchetti, A., Donoghue, A.M., Liyanage, R., Daniels, K.M., Caputi, V., Lyte, M. 2024. Cold stress initiates catecholaminergic and serotonergic responses in the chicken gut that are associated with functional shifts in the microbiome. The ISME Journal: Multidisciplinary Journal of Microbial Ecology. 103(3). Article 103393. https://doi.org/10.1016/j.psj.2023.103393.

Draft genome sequences of Campylobacter species isolated from the cecal contents of broiler chickens - (Peer Reviewed Journal)
Arsi, K., Assumpcao, A., Shyl, D., Donoghue, A.M., Jesudhasan, P. 2024. Draft genome sequences of Campylobacter species isolated from the cecal contents of broiler chickens. Microbiology Resource Announcements. 13(2). Article e00949-23. https://doi.org/10.1128/mra.00949-23.

Inclusion of trans-cinnamaldehyde and caprylic acid in feed results in detectable concentrations in the chicken gut and reduces foodborne pathogen carriage - (Peer Reviewed Journal)
Lyte, J.M., Arsi, K., Caputi, V., Liyanage, R., Assumpcao, A., Jesudhasan, P., Donoghue, A.M. 2023. Inclusion of trans-cinnamaldehyde and caprylic acid in feed results in detectable concentrations in the chicken gut and reduces foodborne pathogen carriage. Poultry Science. 103(2). Article 103368. https://doi.org/10.1016/j.psj.2023.103368.

Leveraging neurochemistry in the design of 21st century feed and microbiota strategies to improve food animal gut health - (Book / Chapter)
Lyte, J.M., Caputi, V. 2024. Leveraging neurochemistry in the design of 21st century feed and microbiota strategies to improve food animal gut health. In: Kogut and Fernandez-Miyakawa editors. Environmental effects on gut health in production animals. Leiden, The Netherlands: Wageningen Academic. 14:304-326.

Impact of heat stress on the chicken cecal bacterial metagenome and luminal serotonin - (Abstract Only)

Complete genome sequence of an avian pathogenic Escherichia coli strain isolated from poultry - (Peer Reviewed Journal)
Jia, X., Phillips, G., Lyte, J.M. 2023. Complete genome sequence of an avian pathogenic Escherichia coli strain isolated from poultry. Microbiology Resource Announcements. 12(10):e0042423. https://doi.org/10.1128/MRA.00424-23.

Effect of plant-derived antimicrobials, eugenol, carvacrol, and ß-resorcylic acid against Salmonella on organic chicken wings and carcasses - (Peer Reviewed Journal)
Nair, D., Manjankattil, S., Peichel, C., Martin, W., Donoghue, A.M., Venkitanarayanan, K., Johny, A.K. 2023. Effect of plant-derived antimicrobials, eugenol, carvacrol, and ß-resorcylic acid against Salmonella on organic chicken wings and carcasses. Poultry Science. 102(10). Article 102866. https://doi.org/10.1016/j.psj.2023.102886.

Litter amendments differentially modulate trace metal concentrations and norepinephrine in the broiler chicken gut - (Abstract Only)

Exopolysaccharides-mediated ZnO nanoparticles for the treatment of aquatic diseases in freshwater fish Oreochromis mossambicus - (Peer Reviewed Journal)

A multiomic analysis of chicken serum revealed the modulation of host factors due to Campylobacter jejuni coloniza-tion and in-water supplementation of eugenol nanoemulsion - (Peer Reviewed Journal)
Wagle, B., Quach, A., Yeo, S., Assumpcao, A., Jesudhasan, P., Arsi, K., Donoghue, A.M. 2023. A multiomic analysis of chicken serum revealed the modulation of host factors due to Campylobacter jejuni coloniza-tion and in-water supplementation of eugenol nanoemulsion. Animals. 13(4). Article 559. https://doi.org/10.3390/ani13040559.

Catecholamine concentrations in duck eggs are impacted by hen exposure to heat stress - (Peer Reviewed Journal)
Lyte, J.M., Daniels, K.M., Lyte, M., Oluwagbenga, E.M., Fraley, G.S. 2023. Catecholamine concentrations in duck eggs are impacted by hen exposure to heat stress. Frontiers in Physiology. 14. Article 1122414. https://doi.org/10.3389/fphys.2023.1122414.

Trans-cinnamaldehyde nanoemulsion wash inactivates Salmonella Enteritidis on shelled eggs without affecting egg color or embryo growth - (Peer Reviewed Journal)
Allem, J., Balasubramanian, B., Rankin, K., Shah, T., Donoghue, A.M., Upadhyaya, I., Sartini, B., Luo, Y., Upadhyay, A. 2023. Trans-cinnamaldehyde nanoemulsion wash inactivates Salmonella Enteritidis on shelled eggs without affecting egg color or embryo growth. Poultry Science. 102(4). Article 102523. https://doi.org/10.1016/j.psj.2023.102523.

The microbiota drives diurnal rhythms in tryptophan metabolism in the stressed gut - (Peer Reviewed Journal)
Gheorghe, C.E., Leigh, S., Tofani, G.S., Bastiaanssen, T.F., Lyte, J.M., Gardellin, E., Martinez-Herrero, S., Goodson, M.S., Kelley-Loughnane, N., Cryan, J.F., Clarke, G. 2024. The microbiota drives diurnal rhythms in tryptophan metabolism in the stressed gut. Cell Reports. 43(4). Article 114079. https://doi.org/10.1016/j.celrep.2024.114079.

Efficacy of pectin-based caproic acid, caprylic acid, linalool and cuminaldehyde coatings in reducing Salmonella Heidelberg on chicken eggs - (Peer Reviewed Journal)
Pellssery, A.J., Vinayamohan, P., Donoghue, A.M., Venkitanarayanan, K. 2022. Efficacy of pectin-based caproic acid, caprylic acid, linalool and cuminaldehyde coatings in reducing Salmonella Heidelberg on chicken eggs. Frontiers in Sustainable Food Systems. 6. Article 874219. https://doi.org/10.3389/fsufs.2022.874219.

Poultry meat and eggs as an alternative source of n-3 long-chain polyunsaturated fatty acids for human nutrition - (Peer Reviewed Journal)
Mancinnelli, A.C., Mattioli, S., Twining, C., Dal Bosco, A., Donoghue, A.M., Arsi, K., Chaittelli, D., Angelucci, E., Castellini, C. 2022. Poultry meat and eggs as an alternative source of n-3 long-chain polyunsaturated fatty acids for human nutrition. Nutrients. 14(9). Article 1969. https://doi.org/10.3390/nu14091969.

Distinct cecal and fecal microbiome responses to stress are accompanied by sex-and diet-dependent changes in behavior and gut serotonin - (Peer Reviewed Journal)
Lyte, J.M., Koester, L., Daniels, K., Lyte, M. 2022. Distinct cecal and fecal microbiome responses to stress are accompanied by sex-and diet-dependent changes in behavior and gut serotonin. Frontiers in Neuroscience. 16. Article 827343. https://doi.org/10.3389/fnins.2022.827343.

A neurochemical biogeography of the broiler chicken intestinal tract - (Peer Reviewed Journal)
Lyte, J.M., Martinez, D.A., Robinson, K., Donoghue, A.M., Daniels, K.M., Lyte, M. 2022. A neurochemical biogeography of the broiler chicken intestinal tract. Poultry Science. 101(30). Article 101671. https://doi.org/10.1016/j.psj.2021.101671.

Exploring the impact of the microbiome on neuroactive steroid levels in germ-free animals - (Peer Reviewed Journal)
Diviccaro, S., Caputi, V., Cioffi, L., Giatti, S., Lyte, J.M., Caruso, D., O'Mahony, S.M., Melcangi, R.C. 2021. Exploring the impact of the microbiome on neuroactive steroid levels in germ-free animals. International Journal of Molecular Sciences. 22(22). Article 12551. https://doi.org/10.3390/ijms222212551.

Impact of feeding bigheaded carp fish meal on meat quality and sensory attributes in organic broiler chickens - (Peer Reviewed Journal)
Upadhyaya, I., Arsi, K., Fanatico, A., Wagle, B.R., Shrestha, S., Upadhyay, A., Coon, C.N., Owens, C.M., Mallman, B., Donoghue, A.M. 2022. Impact of feeding bigheaded carp fish meal on meat quality and sensory attributes in organic broiler chickens. Journal of Applied Poultry Research. 31(1). Article 100224. https://doi.org/10.1016/j.japr.2021.100224.

Informal nutrition symposium: Leveraging the microbiome (and the metabolome) for poultry production - (Peer Reviewed Journal)
Lyte, M., Lyte, J.M. 2022. Informal Nutrition Symposium: Leveraging the microbiome (and the metabolome) for poultry production. Poultry Science. 101(2). Article 101588. https://doi.org/10.1016/j.psj.2021.101588.

Butyrate and forskolin augment host defense, barrier function, and disease resistance without eliciting inflammation - (Peer Reviewed Journal)

Butyrate, forskolin, and lactose synergistically enhance disease resistance of chickens by inducing host defense peptide and barrier function gene expression - (Peer Reviewed Journal)
Yang, Q., Whitmore, M.A., Robinson, K., Lyu, W., Zhang, G. 2021. Butyrate, forskolin, and lactose synergistically enhance disease resistance of chickens by inducing host defense peptide and barrier function gene expression. Antibiotics. 10(10). Article 1175. https://doi.org/10.3390/antibiotics10101175.

Perturbations of the ileal mycobiota by necrotic enteritis in broiler chickens - (Peer Reviewed Journal)

Identification of an intestinal microbiota signature associated with the severity of necrotic enteritis - (Peer Reviewed Journal)
Yang, Q., Liu, J., Wang, X., Robinson, K., Whitmore, M.A., Stewart, S.N., Zhao, J., Zhang, G. 2021. Identification of an intestinal microbiota signature associated with the severity of necrotic enteritis. Frontiers in Microbiology. 12. Article 703693. https://doi.org/10.3389/fmicb.2021.703693.

Identification of an intestinal microbiota signature associated with the severity of necrotic enteritis - (Peer Reviewed Journal)

Select phytochemicals reduce Campylobacter jejuni in postharvest poultry and modulate the virulence attributes of C. jejuni - (Peer Reviewed Journal)
Wagle, B., Donoghue, A.M., Jesudhasan, P. 2021. Select phytochemicals reduce Campylobacter jejuni in postharvest poultry and modulate the virulence attributes of C. jejuni. Frontiers in Microbiology. 12. Article 725087. https://doi.org/10.3389/fmicb.2021.725087.

Early life exposure to cold stress causes distinct changes in broiler chicken gut neurochemistry and microbiome that persist into later life - (Abstract Only)

Sodium butyrate modulates chicken macrophages proteins essential for Salmonella Enteritidis invasion - (Peer Reviewed Journal)
Gupta, A., Bansal, M., Liyanage, R., Upadhyay, A., Rath, N., Donoghue, A.M., Sun, X. 2021. Sodium butyrate modulates chicken macrophages proteins essential for Salmonella Enteritidis invasion. PLoS ONE. 16(4):e0250296. https://doi.org/10.1371/journal.pone.0250296.