Research Project: Analysis of Genetic Factors that Increase Foodborne Pathogen Fitness, Virulence, and Antimicrobial Resistance Transfer, to Identify Interventions against Salmonella and Campylobacter in Food Animals

Location: Food Safety and Enteric Pathogens Research

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Characterizing expression profiles of turkey immune cell populations within peripheral blood using single-cell transcriptomics - (Abstract Only)

Microbiota modulation impacts Salmonella colonization and host gene expression in chickens - (Abstract Only)

A meta-analysis of 16S rRNA amplicon studies to determine a core microbiome in chicken cecal contents - (Abstract Only)

Analysis of a defined consortium on the competitive exclusion of Salmonella in chickens - (Abstract Only)

Avian influenza: discovering mechanisms of host response - (Abstract Only)

A live, attenuated vaccine reduces the human foodborne pathogen Salmonella in commercial poultry - (Abstract Only)

Commercial vaccine provides cross-protection by reducing colonization of salmonella enterica serovars infantis and hadar in turkeys - (Peer Reviewed Journal)
Bearson, S.M., Monson, M.S., Bearson, B.L., Whelan, S.J., Byrd II, J.A., Burciaga, S. 2024. Commercial vaccine provides cross-protection by reducing colonization of salmonella enterica serovars infantis and hadar in turkeys. Vaccine. https://doi.org/10.1016/j.vaccine.2023.12.054.

In feed Bacitracin alters turkey microbiota functional and antibiotic resistance genes in a dose dependent manner - (Abstract Only)

Functional characterization of a microbial consortium for the competitive exclusion of Salmonella in chickens - (Abstract Only)

Competitive exclusion of Salmonella colonization in chickens using a defined community of bacteria - (Abstract Only)

Genomic and phenotypic characterization of multidrug-resistant salmonella enterica serovar reading isolates involved in a turkey-associated foodborne outbreak - (Peer Reviewed Journal)
Sivasankaran, S.K., Bearson, B.L., Trachsel, J.M., Nielsen, D.W., Looft, T.P., Bearson, S.M. 2024. Genomic and phenotypic characterization of multidrug-resistant salmonella enterica serovar reading isolates involved in a turkey-associated foodborne outbreak. Frontiers in Microbiology. https://doi.org/10.3389/fmicb.2023.1304029.

Detection of Salmonella in turkeys by cloacal swab in comparison to intestinal tissue prevalence and colonization - (Abstract Only)

Comparison of the genetic content and arrangement between Salmonella enterica serovars Senftenberg and Infantis - (Abstract Only)

Genomic and phenotypic comparison of two variants of multidrug-resistant Salmonella enterica serovar Heidelberg isolated during the 2015-2017 multi-state outbreak in cattle - (Peer Reviewed Journal)
Burciaga, S., Trachsel, J.M., Sockett, D.C., Aulik, N.A., Monson, M.S., Anderson, C.L., Bearson, S.M. 2023. Genomic and phenotypic comparison of two variants of multidrug-resistant Salmonella enterica serovar Heidelberg isolated during the 2015-2017 multi-state outbreak in cattle. Frontiers in Microbiology. 14: Article 1282832. https://doi.org/10.3389/fmicb.2023.1282832.

Fecal microbiota transplantation reduces Campylobacter jejuni colonization in young broiler chickens challenged by oral gavage but not by seeder birds - (Peer Reviewed Journal)
Pang, J., Beyi, A., Looft, T.P., Zhang, Q., Sahin, O. 2023. Fecal microbiota transplantation reduces Campylobacter jejuni colonization in young broiler chickens challenged by oral gavage but not by seeder birds. Antibiotics. 12(10). Article 1503. https://doi.org/10.3390/antibiotics12101503.

Utilizing reverse vaccinology to identify antigenic epitopes across poultry-relevant serovars for development of a multiepitope, cross-protective Salmonella vaccine - (Abstract Only)

Deciphering the association between Campylobacter colonization and microbiota composition in the intestine of commercial broilers - (Peer Reviewed Journal)
Jinji, P., Looft, T.P., Qijing, Z., Sahin, O. 2023. Deciphering the association between Campylobacter colonization and microbiota composition in the intestine of commercial broilers. Microorganisms. 11(7)1724. https://doi.org/10.3390/microorganisms11071724.

Increasing antimicrobial susceptibility of MDR Salmonella with the efflux pump inhibitor 1-(1-Naphthylmethyl)-piperazine - (Peer Reviewed Journal)
Price, E.D., Dassanayake, R.P., Bearson, S.M. 2023. Increasing antimicrobial susceptibility of MDR Salmonella with the efflux pump inhibitor 1-(1-Naphthylmethyl)-piperazine. Biochemical and Biophysical Research Communications. 668:49-54. https://doi.org/10.1016/j.bbrc.2023.05.035.

On-tissue derivatization of volatile metabolites for matrix assisted laser desorption/ionization mass spectrometry imaging - (Peer Reviewed Journal)
Forsman, T.T., Paulson, A.E., Larson, E.A., Looft, T.P., Lee, Y. 2023. On-tissue derivatization of volatile metabolites for matrix assisted laser desorption/ionization mass spectrometry imaging. Journal of Mass Spectrometry. 58(5). Article e4918. https://doi.org/10.1002/jms.4918.

Genomic and phenotypic characterization of turkey outbreak-associated Salmonella enterica serovar reading - (Abstract Only)

Swine microbiome changes in response to vaccination with Enterisol Salmonella T/C® and challenge with Salmonella enterica I 4,[5],12:i:- - (Abstract Only)

Effects of ß-glucan on Salmonella enterica serovar Typhimurium swine colonization and microbiota alterations - (Peer Reviewed Journal)
Bearson, S.M., Trachsel, J.M., Bearson, B.L., Loving, C.L., Kerr, B.J., Shippy, D.C., Kiros, T.G. 2023. Effects of ß-glucan on Salmonella enterica serovar Typhimurium swine colonization and microbiota alterations. BMC Porcine Health Management. 9(7). Article 003024. https://doi.org/10.1186/s40813-023-00302-4.

Progress toward an immune cell atlas in the chicken - (Abstract Only)

Context matters for antibiotic resistance horizontal gene transfer from commensal bacteria to Salmonella in the chicken gastrointestinal tract - (Abstract Only)

Comparison of multi-drug resistant Salmonella enterica serovar Heidelberg outbreak isolates linked to dairy beef calves - (Abstract Only)

Evaluating two live-attenuated vaccines against outbreak-associated Salmonella enterica serovar reading in turkeys - (Abstract Only)

Effects of ß-glucan on Salmonella enterica serovar Typhimurium swine colonization and microbiota alterations - (Abstract Only)

Antimicrobial resistance in Campylobacter fetus: emergence and genomic evolution - (Peer Reviewed Journal)
van der Graaf-van Bloois, L., Duim, B., Looft, T.P., Veldman, K.T., Zomer, A.L., Wagenaar, J.A. 2023. Antimicrobial resistance in Campylobacter fetus: emergence and genomic evolution. Microbial Genomics. 9(3). https://doi.org/10.1099/mgen.0.000934.

Vaccination of turkeys against Salmonella enterica serovar Infantis: effects on the cecal microbiome and tissue colonization - (Abstract Only)

Proteomic response of Turicibacter bilis MMM721 to chicken bile and its bile acids - (Peer Reviewed Journal)
Maki, J.J., Lippolis, J.D., Looft, T.P. 2022. Proteomic response of Turicibacter bilis MMM721 to chicken bile and its bile acids. BMC Research Notes. 15(1). Article e236. https://doi.org/10.1186/s13104-022-06127-8.

Short chain fatty acids and bacterial taxa associated with reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in swine fed a diet supplemented with resistant potato starch - (Peer Reviewed Journal)
Trachsel, J.M., Bearson, B.L., Kerr, B.J., Shippy, D.C., Byrne, K.A., Loving, C.L., Bearson, S.M. 2022. Short chain fatty acids and bacterial taxa associated with reduced Salmonella enterica serovar I 4,[5],12:i:- Shedding in swine fed a diet supplemented with resistant potato starch. Microbiology Spectrum. 10(3). Article e0220221. https://doi.org/10.1128/spectrum.02202-21.

Gene signatures for intestinal and peripheral innate lymphoid cells in pigs reveal tissue-specific imprinting and similarities to human cells via single-cell RNA sequencing in pigs - (Abstract Only)

Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database - (Peer Reviewed Journal)
Trachsel, J.M., Bearson, B.L., Brunelle, B.W., Bearson, S.M. 2022. Relationship and distribution of Salmonella enterica serovar I 4,[5],12:i:- strain sequences in the NCBI Pathogen Detection database. Biomed Central (BMC) Genomics. 23(1). Article 268. https://doi.org/10.1186/s12864-022-08458-z.

Low-path avian influenza infection induces distinct gene expression responses in vivo and in vitro in diverse chicken lines - (Abstract Only)