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ARS Home » Northeast Area » Beltsville, Maryland (BHNRC) » Beltsville Human Nutrition Research Center » Methods and Application of Food Composition Laboratory » People & Locations » Jianghao Sun
Jianghao Sun
Methods and Application of Food Composition Laboratory
RESEARCH CHEMIST

Phone: (301) 504-8254
Fax:

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Projects
Foodomics: New Tools for Food Composition
In-House Appropriated (D)
  Accession Number: 445346
Farm to Table Factors: Impact of Production, Processing, and Preparation on Food Composition
In-House Appropriated (D)
  Accession Number: 445356
High Resolution Mass Spectral Database for Herbs and Foods
Non-Assistance Cooperative Agreement (S)
  Accession Number: 446372
Analysis of Secondary Metabolites in Plants
Non-Assistance Cooperative Agreement (S)
  Accession Number: 446458
Advanced Technology for Rapid Comprehensive Analysis of the Chemical Components of Foods
Non-Assistance Cooperative Agreement (S)
  Accession Number: 446477
High Resolution Mass Spectral Database for Herbs and Foods
Non-Assistance Cooperative Agreement (S)
  Accession Number: 444051
Advanced Technology for Rapid Comprehensive Analysis of the Chemical Components of Foods
Non-Assistance Cooperative Agreement (S)
  Accession Number: 444067

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Metabolic pathway and network analysis integration for discovering the biomarkers in pig feces after a controlled fruit-vegetable dietary intervention Reprint Icon - (Peer Reviewed Journal)
Liu, Z., Solano Aguilar, G., Lakshman, S., Urban, J.F., Zhang, M., Chen, P., Yu, L., Sun, J. 2024. Metabolic pathway and network analysis integration for discovering the biomarkers in pig feces after a controlled fruit-vegetable dietary intervention. Food Chemistry. 461:140836. https://doi.org/10.1016/j.foodchem.2024.140836.
Chemical composition of turmeric (Curcuma longa L.) ethanol extract and its antimicrobial activities and free radical scavenging capacities Reprint Icon - (Peer Reviewed Journal)
Wu, H., Liu, Z., Zhang, Y., Gao, B., Li, Y., He, X., Sun, J., Choe, U., Chen, P., Blaustein, R., Yu, L. 2024. Chemical composition of turmeric (Curcuma longa L.) ethanol extract and its antimicrobial activities and free radical scavenging capacities. Foods. 13(10). Article 1550. https://doi.org/10.3390/foods13101550.
Effect of far-red light on biomass accumulation, plant morphology, and phytonutrient composition of ruby streaks mustard at microgreen, baby leaf, and flowering stages Reprint Icon - (Peer Reviewed Journal)
Teng, Z., Luo, Y., Sun, J., Pearlstein, D.J., Oehler, M., Fitzwater, J.D., Zhou, B., Hussan, M.A., Chang, C.Y., Chen, P., Wang, Q., Fonseca, J.M. 2024. Effect of far-red light on biomass accumulation, plant morphology, and phytonutrient composition of ruby streaks mustard at microgreen, baby leaf, and flowering stages. Journal of Agricultural and Food Chemistry. 72(17):9587–9598. https://doi.org/10.1021/acs.jafc.3c06834.
Fast and simple solid phase extraction-based method for glucosinolate determination: an alternative to ISO-9167 method Reprint Icon - (Peer Reviewed Journal)
Li, Y., Zhang, M., Pehrsson, P.R., Harnly, J.M., Chen, P., Sun, J. 2024. Fast and simple solid phase extraction-based method for glucosinolate determination: an alternative to ISO-9167 method. Foods. 13(5):650. https://doi.org/10.3390/foods13050650.
Chemical compositions of Scutellaria baicalensis Georgi. (Huangqin) extracts and their effects on ACE2 binding of SARS-CoV-2 spike protein, ACE2 activity, and free radicals Reprint Icon - (Peer Reviewed Journal)
Gao, B., Zhu, H., Liu, Z., He, X., Sun, J., Li, Y., Wu, X., Pehrsson, P.R., Zhang, Y., Yu, L. 2024. Chemical compositions of Scutellaria baicalensis Georgi. (Huangqin) extracts and their effects on ACE2 binding of SARS-CoV-2 spike protein, ACE2 activity, and free radicals. International Journal of Molecular Sciences. 25(4). Article 2045. https://doi.org/10.3390/ijms25042045.
Study of uv-vis molar absorptivity variation and quantitation of anthocyanins using molar relative response factor Reprint Icon - (Peer Reviewed Journal)
Dong, W., Yang, X., Chen, P., Sun, J., Harnly, J.M., Zhang, M., Zhang, N. 2024. Study of uv-vis molar absorptivity variation and quantitation of anthocyanins using molar relative response factor. Food Chemistry. 444:138653. https://doi.org/10.1016/j.foodchem.2024.138653.
Variability and determinants of secondary metabolite profiles in cranberries (Vaccinium macrocarpon) from key cultivation states Reprint Icon - (Peer Reviewed Journal)
Geng, P., Harnly, J.M., Sun, J., Chen, P. 2024. Variability and determinants of secondary metabolite profiles in cranberries (Vaccinium macrocarpon) from key cultivation states. Journal of Agriculture and Food Research. 15:100983. https://doi.org/10.1016/j.jafr.2024.100983.
Chemical composition of thyme (Thymus vulgaris) extracts and potential inhibition of SARS-CoV-2 spike protein-ACE2 binding and ACE-2 expression, and radical scavenging capacity Reprint Icon - (Peer Reviewed Journal)
Yao, Y., Li, Y., Whent, M.M., Pehrsson, P.R., Sun, J., Chen, P., Wu, X., Huang, D., Yu, L. 2023. Chemical composition of thyme (Thymus vulgaris) extracts and potential inhibition of SARS-CoV-2 spike protein-ACE2 binding and ACE-2 expression, and radical scavenging capacity. Journal of Agricultural and Food Chemistry. 71(49):19523-19530. https://doi.org/10.1021/acs.jafc.3c05432.
The chemical constituents of parsley (petroselinum crispum) leaf extract and its potential in mitigating the effects of viral infections Reprint Icon - (Peer Reviewed Journal)
Lee, E.Y., Liu, Z., Li, Y., Wang, T.T., Sun, J., Wu, X., Whent, M.M., Pehrsson, P.R., Zhang, Y., Gao, B., Yao, Y., Yu, L. 2023. The chemical constituents of parsley (petroselinum crispum) leaf extract and its potential in mitigating the effects of viral infections. ACS Food Science and Technology. 3(12):2108-2116. https://doi.org/10.1021/acsfoodscitech.3c00357.
Chemical compositions of dill (Anethum graveolens L.) water and ethanol extracts and their potential in reducing the COVID-19 risk and free radical scavenging capacities Reprint Icon - (Peer Reviewed Journal)
Choe, U., Liu, Z., Li, Y., Sun, J., Wu, X., Pehrsson, P.R., Xie, Z., Zhang, Y., Wang, T.T., Yu, L., Gao, B. 2023. Chemical compositions of dill (Anethum graveolens L.) water and ethanol extracts and their potential in reducing the COVID-19 risk and free radical scavenging capacities. Food Chemistry. 3(10):1654–1662. https://doi.org/10.1021/acsfoodscitech.3c00206?urlappend=%3Fref%3DPDF&jav=VoR&rel=cite-as.
Improved metabolomic approach for evaluation of phytochemicals in mustard, kale, and broccoli microgreens under different controlled environmental agriculture conditions Reprint Icon - (Peer Reviewed Journal)
Li, Y., Zhou, B., Teng, Z., Zhang, M., Yu, L., Luo, Y., Chen, P., Sun, J. 2023. Improved metabolomic approach for evaluation of phytochemicals in mustard, kale, and broccoli microgreens under different controlled environmental agriculture conditions. Journal of Agriculture and Food Research. 14: 100719. https://doi.org/10.1016/j.jafr.2023.100719.
An untargeted metabolomics approach to study the variation between wild and cultivated soybeans Reprint Icon - (Peer Reviewed Journal)
Tareq, F.S., Kotha, R.R., Natarajan, S.S., Sun, J., Luthria, D.L. 2023. An untargeted metabolomics approach to study the variation between wild and cultivated soybeans. Molecules. 28(14):5507. https://doi.org/10.3390/molecules28145507.
Steroidal glycoalkaloids contribute to anthracnose resistance in solanum lycopersicum Reprint Icon - (Peer Reviewed Journal)
Fabian, M.L., Zhang, C., Sun, J., Price, N.P., Chen, P., Clarke, C.R., Jones, R.W., Stommel, J.R. 2023. Steroidal glycoalkaloids contribute to anthracnose resistance in solanum lycopersicum. Journal of Experimental Botany. 74(12):3700-3713. https://doi.org/10.1093/jxb/erad108.
Chemical composition of honeysuckle (Lonicerae japonicae) extracts and their potential in inhibiting the SARS-CoV-2 spike protein and ACE2 binding, suppressing ACE2, and scavenging radicals Reprint Icon - (Peer Reviewed Journal)
Gao, B., Zhu, L., Liu, Z., Li, Y., He, X., Wu, X., Pehrsson, P.R., Sun, J., Xie, Z., Slavin, M., Yu, L. 2023. Chemical composition of honeysuckle (Lonicerae japonicae) extracts and their potential in inhibiting the SARS-CoV-2 spike protein and ACE2 binding, suppressing ACE2, and scavenging radicals. Journal of Agricultural and Food Chemistry. 71(15):6133-6143. https://doi.org/10.1021/acs.jafc.3c00584.
Chemical characterization of cinnamon (Cinnamomum verum J. Presl) extracts and their capacities in weakening SARS-CoV-2 spike protein binding to ACE2, inhibiting ACE2 and scavenging free radicals Reprint Icon - (Peer Reviewed Journal)
Xie, Z., Li, Y., Liu, Z., Zeng, M., Moore, J., Gao, B., Wu, X., Sun, J., Wang, T.T., Pehrsson, P.R., He, X., Yu, L. 2023. Chemical characterization of cinnamon (Cinnamomum verum J. Presl) extracts and their capacities in weakening SARS-CoV-2 spike protein binding to ACE2, inhibiting ACE2 and scavenging free radicals. Journal of Agricultural and Food Chemistry. 71:4890-4900. https://doi.org/10.1021/acs.jafc.3c00285.
Chemical compositions of clove (Syzygium aromaticum (L.) Merr. & L.) extracts and their potentials in suppressing SARS-CoV-2 spike protein-ACE2 binding, inhibiting ACE2, and scavenging free radicals Reprint Icon - (Peer Reviewed Journal)
Li, Y., Liu, Z., Zeng, M., El Kadiri, A., Huang, J., Kim, A., He, X., Sun, J., Chen, P., Wang, T.T., Zhang, Y., Gao, B., Xie, Z., Yu, L. 2022. Chemical compositions of clove (Syzygium aromaticum (L.) Merr. & L.) extracts and their potentials in suppressing SARS-CoV-2 spike protein-ACE2 binding, inhibiting ACE2, and scavenging free radicals. Journal of Agricultural and Food Chemistry. 70(45):14403-14413. https://doi.org/10.1021/acs.jafc.2c06300.
Effect of thermal treatments on soluble-free, soluble-conjugated, and insoluble-bound phenolic components and free radical scavenging properties of tomato seeds Reprint Icon - (Peer Reviewed Journal)
Li, Y., Wu, K., Liu, Z., He, X., Sun, J., Zeng, M., Lee, S., Wang, T.T., Gao, B., Xie, Z., Wei, C., Yu, L. 2022. Effect of thermal treatments on soluble-free, soluble-conjugated, and insoluble-bound phenolic components and free radical scavenging properties of tomato seeds. ACS Food Science and Technology. 2(10):1631-1638. https://doi.org/10.1021/acsfoodscitech.2c00228.
Effects of different light-emitting diode illumination on bioactive compounds in mustard “Ruby Streak” microgreens by Ultra-high Performance Liquid Chromatography High-Resolution Mass Spectrometry Reprint Icon - (Peer Reviewed Journal)
Liu, Z., Teng, Z., Pearlstein, D.J., Chen, P., Yu, L., Zhou, B., Luo, Y., Sun, J. 2022. Effects of different light-emitting diode illumination on bioactive compounds in mustard “Ruby Streak” microgreens by ultra-high performance liquid chromatography high-resolution mass spectrometry. ACS Food Science and Technology. 2(9):1483–1494. https://doi.org/10.1021/acsfoodscitech.2c00193.
Identification of soluble free, soluble conjugated and insoluble bound phenolics in tomato seeds and their radical scavenging and antiproliferative activities Reprint Icon - (Peer Reviewed Journal)
Li, Y., Liu, Z., Tamia, G., He, X., Sun, J., Chen, P., Lee, S., Wang, T.T., Gao, B., Xie, Z., Yu, L. 2022. Identification of soluble free, soluble conjugated and insoluble bound phenolics in tomato seeds and their radical scavenging and antiproliferative activities. Journal of Agricultural and Food Chemistry. 70(29):9039-9047. https://pubs.acs.org/doi/10.1021/acs.jafc.2c03418.
Mass Spectrometry Based Non-Targeted and Targeted Analytical Approaches in Fingerprinting and Metabolomics of Food and Agricultral Research Reprint Icon - (Review Article)
Zhihao, L., Mengliang, Z., Chen, P., Harnly, J.M., Sun, J. 2022. Mass spectrometry based non-targeted and targeted analytical approaches in fingerprinting and metabolomics of food and agricultral research. Journal of Agriculture and Food Chemistry. 70(36):11138–11153. https://doi.org/10.1021/acs.jafc.2c01878.
Contrast study on secondary metabolite profile between pastas made from three single varietal common bean (Phaseolus vulgaris L.) and durum wheat (Triticum durum) Reprint Icon - (Peer Reviewed Journal)
Geng, P., Hooper, S., Sun, J., Chen, P., Cichy, K.A., Harnly, J.M. 2022. Contrast study on secondary metabolite profile between pastas made from three single varietal common bean (Phaseolus vulgaris L.) and durum wheat (Triticum durum). ACS Food Science and Technology. 2(5):895–904. https://doi.org/10.1021/acsfoodscitech.2c00050.
Comparison of Phytochemical Profile of Wild and Cultivated American Ginseng using Metabolomics by Ultra-High Performance Liquid Chromatography-High-Resolution Mass Spectrometry Reprint Icon - (Peer Reviewed Journal)
Liu, Z., Gao, Y., Chen, P., Moore, R., Sun, J., Zhang, M. 2022. Comparison of Phytochemical Profile of Wild and Cultivated American Ginseng using Metabolomics by Ultra-High Performance Liquid Chromatography-High-Resolution Mass Spectrometry. Molecules. 28:1. https://doi.org/10.3390/molecules28010009.
Profiling of polyphenols and glucosinolates in kale and broccoli microgreens grown under chamber and windowsill conditions by ultrahigh-performance liquid chromatography high-resolution mass spectrometry Reprint Icon - (Peer Reviewed Journal)
Liu, Z., Shi, J., Wan, J., Pham, Q., Zhang, Z., Sun, J., Yu, L., Luo, Y., Wang, T.T.Y., Chen, P. 2021. Profiling of polyphenols and glucosinolates in kale and broccoli microgreens grown under chamber and windowsill conditions by ultrahigh-performance liquid chromatography high-resolution mass spectrometry. ACS Food Science and Technology. 2(1):101-113. https://doi.org/10.1021/acsfoodscitech.1c00355.
Classification of structural characteristics facilitate identifying steroidal saponins inAlliums using ultra-high performance liquid chromatography high-resolution massspectrometry Reprint Icon - (Peer Reviewed Journal)
Geng, P., Chen, P., Lin, L., Sun, J., Harrington, P., Harnly, J.M. 2021. Classifi cation of structural characteristics facilitate identifying steroidal saponins inAlliums using ultra-high performance liquid chromatography high-resolution massspectrometry . Journal of Food Composition and Analysis. 102:103994. https://doi.org/10.1016/j.jfca.2021.103994.
Chemical composition of tomato seed flours, and their radical scavenging, anti-inflammatory and gut microbiota modulating properties Reprint Icon - (Peer Reviewed Journal)
Choe, U., Sun, J., Bailoni, E., Chen, P., Li, Y., Goa, B., Wang, T.T., Rao, J., Yu, L. 2021. Chemical composition of tomato seed flours, and their radical scavenging, anti-inflammatory and gut microbiota modulating properties. Molecules. 26(5):1478. https://doi.org/10.3390/molecules26051478.
Effect of nighttime UV-C irradiation of strawberry plants on phenolic content of fruit: targeted and non-targeted metabolomic analysis Reprint Icon - (Peer Reviewed Journal)
Sun, J., Janisiewicz, W.J., Takeda, F., Evans, B.E., Jurick Ii, W.M., Zhang, M., Yu, L., Chen, P. 2020. Effect of nighttime UV-C irradiation of strawberry plants on phenolic content of fruit: targeted and non-targeted metabolomic analysis. Journal of Berry Research. 10(3):365-380. https://doi.org/10.3233/JBR-190482.
Microgreens of Brassicaceae: Genetic diversity of phytochemical concentrations and antioxidant capacities - (Peer Reviewed Journal)
Xiao, Z., Rausch, S.R., Luo, Y., Sun, J., Yu, L., Wang, Q., Chen, P., Yu, L., Stommel, J.R. 2018. Microgreens of Brassicaceae: Genetic diversity of phytochemical concentrations and antioxidant capacities. LWT - Food Science and Technology. 101:731-737.
Challenges of developing a valid Dietary Glucosinolate database Reprint Icon - (Peer Reviewed Journal)
Wu, X., Sun, J., Haytowitz, D.B., Harnly, J.M., Chen, P., Pehrsson, P.R. 2017. Challenges of developing a valid Dietary Glucosinolate database. Journal of Food Composition and Analysis. https://doi.org/10.1016/j.jfca.2017.07.014.
Develop a Comprehensive Flavonoid Analysis Computational Tool for UHPLC-DAD- HRAM-MSn Data - (Peer Reviewed Journal)
Zhang, M., Sun, J., Chen, P. 2017. Develop a Comprehensive Flavonoid Analysis Computational Tool for UHPLC-DAD- HRAM-MSn Data. Analytical Chemist. 89 (4):7388-7397.
Botanical supplements: detecting the transition from ingredients to supplements Reprint Icon - (Peer Reviewed Journal)
Harnly, J.M., Lu, Y., Sun, J., Chen, P. 2017. Botanical supplements: detecting the transition from ingredients to supplements. Journal of Food Composition and Analysis. 64:85-92. https://doi.org/10.1016/j.jfca.2017.06.010.
Composition of phenolic compounds in wild apple with multiple resistance mechanisms against postharvest blue mold decay - (Peer Reviewed Journal)
Sun, J., Janisiewicz, W.J., Evans, B.E., Jurick II, W.M., Chen, P. 2017. Composition of phenolic compounds in wild apple with multiple resistance mechanisms against postharvest blue mold decay. Postharvest Biology and Technology. 127:68-75.
Feruloyl dopamine-O-hexosides are efficient marker compounds for differentiation between Black Cohosh (Actaea racemosa) and related Actaea species – an UHPLC-HRAM-MS Chemometrics Study Reprint Icon - (Peer Reviewed Journal)
Geng, P., Harnly, J.M., Sun, J., Zhang, M., Chen, P. 2017. Feruloyl dopamine-O-hexosides are efficient marker compounds for differentiation between Black Cohosh (Actaea racemosa) and related Actaea species – an UHPLC-HRAM-MS Chemometrics Study. Analytical and Bioanalytical Chemistry. 127:68-75. https://doi.org/10.1016/j.postharvbio.2017.01.006.
Comprehensive characterization of C-glycosyl flavones in wheat (Triticum aestivum L.) germ using UPLC-PDA-ESI/HRMSn and mass defect filtering - (Peer Reviewed Journal)
Geng, P., Sun, J., Zhang, M., Li, X., Harnly, J.M., Chen, P. 2016. Comprehensive characterization of C-glycosyl flavones in wheat (Triticum aestivum L.) germ using UPLC-PDA-ESI/HRMSn and mass defect filtering. Journal of Mass Spectrometry. 64:4407-4415.
GLS-Finder: An Automated Data-Mining System for Fast Profiling Glucosinolates and its Application in Brassica Vegetables - (Peer Reviewed Journal)
Sun, J., Zhang, M., Chen, P. 2016. GLS-Finder: An Automated Data-Mining System for Fast Profiling Glucosinolates and its Application in Brassica Vegetables. Analytical Chemistry. 4407:4415.
Myrosinase-dependent and –independent formation and control of isothiocyanate products of glucosinolate hydrolysis - (Peer Reviewed Journal)
Angelino, D., Dosz,.B., Sun, J., Hoeflinger, J.L., Van Tassell, M.L., Chen, P., Harnly, J.M., Miller, M.J., Jeffery, E.H. 2015. Myrosinase-dependent and –independent formation and control of isothiocyanate products of glucosinolate hydrolysis. Frontiers in Plant Science. doi: 10.3389/fpls.2015.00831.
FlavonQ: An Automated Data Processing Tool for Profiling Flavone/flavonol Glycosides Using Ultra High-performance Liquid Chromatography Diode Array Detection and High-Resolution Accurate-Mass Mass Spectrometry (UHPLC HRAM-MS) - (Peer Reviewed Journal)
Zhang, M., Sun, J., Chen, P. 2015. FlavonQ: An Automated Data Processing Tool for Profiling Flavone/flavonol Glycosides Using Ultra High-performance Liquid Chromatography Diode Array Detection and High-Resolution Accurate-Mass Mass Spectrometry (UHPLC HRAM-MS). Analytical Chemist. 87:9974-9981.
Comparison of Flow Injection MS, NMR, and DNA Sequencing: Methods for Identification and Authentication of Black Cohosh (Actaea racemosa) - (Peer Reviewed Journal)
Harnly, J.M., Chen, P., Sun, J., Huang, H., Colson, K., Yu, J., Mccoy, J.H., Harbaugh Reynaud, D.T., Harrington, P.B., Fletcher, E. 2015. Comparison of Flow Injection MS, NMR, and DNA Sequencing: Methods for Identification and Authentication of Black Cohosh (Actaea racemosa). Planta Medica. 82:250-262.
Metabolomic assessment reveals a stimulatory effect of calcium treatment on glucosinolates contents in broccoli microgreen Reprint Icon - (Peer Reviewed Journal)
Sun, J., Kou, L., Geng, P., Huang, H., Yang, T., Luo, Y., Chen, P. 2015. Metabolomic assessment reveals a stimulatory effect of calcium treatment on glucosinolates contents in broccoli microgreen. Journal of Agricultural and Food Chemistry. 8:63(6):1863-1868.
Characterization of phenolic amides from cortex lycii by ultra high-performance liquid chromatography coupled with LTQ-Orbitrap mass spectrometry - (Peer Reviewed Journal)
Zhang, J., Guan, S., Sun, J., Liu, T., Chen, P., Feng, R., Chen, X., Hou, J., Yang, W., Wu, W., Yang, M., Guo, D. 2014. Characterization of phenolic amides from cortex lycii by ultra high-performance liquid chromatography coupled with LTQ-Orbitrap mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 407:581-95.
High fat diet leads to changes in metabolite patterns in pig plasma, fecal, and urine samples detected by a ultra-high performance liquid chromatography tandem with high resolution mass spectrometry metabolomic study - (Peer Reviewed Journal)
Sun, J., Monagas, M., Jang, S., Molokin, A., Harnly, J.M., Urban, J.F., Aguilar, G., Chen, P. 2014. High fat diet leads to changes in metabolite patterns in pig plasma, fecal, and urine samples detected by a ultra-high performance liquid chromatography tandem with high resolution mass spectrometry metabolomic study. Food Chemistry. 15:173:171-178.
Profiling of Glucosinolates and Flavonoids in Rorippa indica (Linn.) Hiern. (Cruciferae) by UHPLC-PDA-ESI/HRMSn. - (Peer Reviewed Journal)
Lin, L., Sun, J., Chen, P., Zhang, R., Fan, X., Li, L., Harnly, J.M. 2014. UHPLC-DAD-ESI/HRMSn method to identify the glucosinolates and flavonoids of Rorippa montana (Wall) Small.. Journal of Agricultural and Food Chemistry. 62:6118-6129.
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